The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

2000 • 654 citations

Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite.

1994 • 532 citations

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

1998 • 528 citations

Sphingosine Kinase Type 2 Is a Putative BH3-only Protein That Induces Apoptosis

2003 • 352 citations

Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment

2003 • 281 citations

First Human Trial of FTY720, a Novel Immunomodulator, in Stable Renal Transplant Patients

2002 • 272 citations

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

2002 • 265 citations

Purification and Characterization of Rat Kidney Sphingosine Kinase

1998 • 221 citations

Enzymatic Measurement of Sphingosine 1-Phosphate

1999 • 182 citations

Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus.

2002 • 120 citations

Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats

2000 • 71 citations

The immune modulator FYT720 prevents autoimmune diabetes in nonobese diabetic mice☆

2003 • 61 citations

FTY720: A new kid on the block for transplant immunosuppression

2003 • 21 citations