Comparison of the actions of adenosine at pre‐ and postsynaptic receptors in the rat hippocampus in vitro.

Subclasses of external adenosine receptors.

1980 • 1,087 citations

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1981 • 1,044 citations

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

Organotypic monolayer cultures of nervous tissue

1981 • 862 citations

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1985 • 736 citations

The Coupling of Neurotransmitter Receptors to Ion Channels in the Brain

1988 • 732 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels

1986 • 666 citations

Potentiation of synaptic transmission in the hippocampus by phorbol esters

1986 • 647 citations

A physiological role for GABAB receptors in the central nervous system

1988 • 643 citations

The Physiological Role of Adenosine In The Central Nervous System

1985 • 628 citations

GABAB autoreceptors regulate the induction of LTP

1991 • 613 citations

Persistent protein kinase activity underlying long-term potentiation

1988 • 557 citations

Neurotransmitters decrease the calcium conductance activated by depolarization of embryonic chick sensory neurones.

1981 • 555 citations

Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: I. Receptor Characterisation

1984 • 517 citations

Comparison of the actions of adenosine at pre‐ and postsynaptic receptors in the rat hippocampus in vitro.

1992 • 486 citations

GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures.

1985 • 468 citations

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) ? a selective high affinity antagonist radioligand for A1 adenosine receptors

1987 • 390 citations

Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre

1982 • 390 citations

Giant Synaptic Potential Hypothesis for Epileptiform Activity

1981 • 371 citations

Pre- and postsynaptic GABAB receptors in the hippocampus have different pharmacological properties

1988 • 368 citations

Protein kinase C regulates ionic conductance in hippocampal pyramidal neurons: electrophysiological effects of phorbol esters.

1985 • 361 citations

Phaclofen: a peripheral and central baclofen antagonist

1987 • 349 citations

Convergence and divergence of neurotransmitter action in human cerebral cortex.

1989 • 349 citations

Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H]CGS 21680

1989 • 344 citations

Direct hyperpolarizing action of baclofen on hippocampal pyramidal cells

1984 • 342 citations

Calcium channel currents and their inhibition by (‐)‐baclofen in rat sensory neurones: modulation by guanine nucleotides.

1987 • 342 citations

A bicuculline‐resistant inhibitory post‐synaptic potential in rat hippocampal pyramidal cells in vitro.

1984 • 331 citations

Activity-dependent disinhibition. I. Repetitive stimulation reduces IPSP driving force and conductance in the hippocampus in vitro

1989 • 328 citations

‘Crosstalk’: a pivotal role for protein kinase C in modulating relationships between signal transduction pathways

1991 • 328 citations

CGP 35348: a centrally active blocker of GABAB receptors

1990 • 303 citations

Enkephalin hyperpolarizes interneurones in the rat hippocampus.

1988 • 296 citations

Calcium‐dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.

1986 • 256 citations

Dependence of an adenosine-activated potassium current on a GTP-binding protein in mammalian central neurons

1987 • 254 citations

Classification of muscarinic responses in hippocampus in terms of receptor subtypes and second-messenger systems: electrophysiological studies in vitro

1988 • 249 citations

Pertussis toxin reverses adenosine inhibition of neuronal glutamate release

1985 • 247 citations

Newly Identified Brain Potassium Channels Gated by the Guanine Nucleotide Binding Protein G _o

1988 • 236 citations

Phorbol esters enhance transmitter release in rat hippocampal slices

1987 • 228 citations

Development of the hippocampus in vitro: Cell types, synapses and receptors

1984 • 210 citations

Mechanism of action of the phorbol ester tumor promoters: Specific receptors for lipophilic ligands

1984 • 209 citations

Adenosine A1 receptors inhibit adenylate cyclase activity and neurotransmitter release and hyperpolarize pyramidal neurons in rat hippocampus.

1989 • 200 citations

Changes in brain adenosine during bicuculline-induced seizures in rats. Effects of hypoxia and altered systemic blood pressure.

1980 • 196 citations

Purinergic mechanisms in epilepsy

1988 • 190 citations

Adenosine agonists reduce voltage‐dependent calcium conductance of mouse sensory neurones in cell culture.

1986 • 188 citations

Baclofen reduces post‐synaptic potentials of rat cortical neurones by an action other than its hyperpolarizing action.

1987 • 187 citations

Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus

1991 • 184 citations

Alkylxanthines elevate hippocampal excitability

1981 • 178 citations

Activity-dependent disinhibition. III. Desensitization and GABAB receptor-mediated presynaptic inhibition in the hippocampus in vitro

1989 • 177 citations

Intracellular analysis of a postsynaptic action of adenosine in the rat hippocampus

1982 • 167 citations

Analysis of adenosine actions on Ca2+ currents and synaptic transmission in cultured rat hippocampal pyramidal neurones.

1991 • 165 citations

Baclofen selectively inhibits excitatory synaptic transmission in the hippocampus

1981 • 161 citations

Levels of adenosine and adenine nucleotides in slices of rat hippocampus

1984 • 160 citations

Characterization of inhibition mediated by adenosine in the hippocampus of the rat in vitro.

1989 • 160 citations

Protein kinase C activators block specific calcium and potassium current components in isolated hippocampal neurons

1988 • 160 citations

On the presynaptic action of baclofen at inhibitory synapses between cultured rat hippocampal neurones.

1990 • 154 citations

Electrophysiological characterization of potent agonists and antagonists at pre‐ and postsynaptic GABA_B receptors on neurones in rat brain slices

1990 • 152 citations

Inhibitory action of adenosine on synaptic transmission in the hippocampus of the guinea pig in vitro

1980 • 143 citations

Specific inhibitors of protein kinase C block transmitter-induced modulation of sensory neuron calcium current

1989 • 130 citations

Adenosine actions on CA1 pyramidal neurones in rat hippocampal slices.

1985 • 127 citations

Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus

1991 • 124 citations

Effects of (?)baclofen on inhibitory neurons in the guinea pig hippocampal slice

1989 • 116 citations

Adenosine inhibits calcium spikes in hippocampal pyramidal neurons in vitro

1983 • 114 citations

Pre- and postsynaptic actions of adenosine in the in vitro rat hippocampus

1987 • 106 citations

Endogenous adenosine inhibits hippocampal CA1 neurones: further evidence from extra- and intracellular recording

1988 • 100 citations

Role of EPSPs in initiation of spontaneous synchronized burst firing in rat hippocampal neurons bathed in high potassium

1990 • 100 citations

Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked neurotransmitter actions: electrophysiological studies in rat hippocampus.

1987 • 94 citations

An investigation into the mechanisms of inhibition of calcium channel currents in cultured sensory neurones of the rat by guanine nucleotide analogues and (−)− baclofen

1989 • 69 citations

Phaclofen inhibition of the slow inhibitory postsynaptic potential in hippocampal slice cultures: A possible role for the GABAB-mediated inhibitory postsynaptic potential

1990 • 66 citations

Phaclofen‐insensitive presynaptic inhibitory action of (±)‐baclofen in neonatal rat motoneurones in vitro

1990 • 65 citations

Pertussis toxin pretreatment discriminates between pre- and postsynaptic actions of baclofen in rat dorsal raphe nucleus in vitro

1988 • 63 citations

Transient and selective blockade of adenosine A1-receptors by 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) causes sustained epileptiform activity in hippocampal CA3 neurons of guinea pigs

1989 • 58 citations

Actions of the GABA_B agonist, (−)‐baclofen, on neurones in deep dorsal horn of the rat spinal cord in vitro

1989 • 55 citations

Presynaptic inhibition by neuropeptide Y and baclofen in hippocampus: insensitivity to pertussis toxin treatment

1989 • 54 citations

In vivo pertussis toxin treatment attenuates some, but not all, adenosine A1 effects in slices of the rat hippocampus

1989 • 53 citations

2‐Chloroadenosine reduces the N calcium current of cultured mouse sensory neurones in a pertussis toxin‐sensitive manner.

1989 • 52 citations

Somatically recorded Ca-currents in guinea-pig hippocampal and olfactory cortex neurones are resistant to adenosine action

1984 • 47 citations

Adenosine A1 and non-A1 receptors: Intracellular analysis of the actions of adenosine agonists and antagonists in rat hippocampal neurones

1991 • 45 citations

Adenosine A1 receptor activation mediates suppression of (-) bicuculline methiodide-induced seizures in rat prepiriform cortex.

1989 • 39 citations

Intrahippocampal injection of pertussis toxin blocks adenosine suppression of synaptic responses

1989 • 39 citations

Pertussis toxin blocks a late inhibitory postsynaptic potential in hippocampal CA3 neurons

1987 • 38 citations

Baclofen-induced disinhibition in area CA1 of rat hippocampus is resistant to extracellular Ba2+

1991 • 33 citations

3-aminopropanephosphinic acid is a potent agonist at peripheral and central presynaptic GABAB receptors

1990 • 28 citations

Adenosinergic inhibition in hippocampus is mediated by adenosine A1 receptors very similar to those of peripheral tissues

1991 • 25 citations

Arachidonic acid metabolites do not mediate modulation of neurotransmitter release by adenosine in rat hippocampus or striatum

1990 • 18 citations