Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: Enhanced IL-13 production by IL-4–primed human mast cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

1989 • 1,989 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 • 1,199 citations

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.

1992 • 1,168 citations

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

1993 • 1,084 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1993 • 877 citations

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

1995 • 760 citations

Establishment of an immature mast cell line from a patient with mast cell leukemia

1988 • 749 citations

Mast cells as a source of multifunctional cytokines

1990 • 708 citations

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.

1990 • 679 citations

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

1993 • 657 citations

Interleukin 4 is localized to and released by human mast cells.

1992 • 589 citations

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.

1993 • 565 citations

Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation.

1993 • 561 citations

Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation

1989 • 494 citations

Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction.

1993 • 457 citations

IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells.

1995 • 424 citations

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor.

1996 • 406 citations

Activated mast cells produce interleukin 13.

1995 • 320 citations

Human mast cells produce IL-8.

1993 • 302 citations

Interleukin 13 is a B cell stimulating factor.

1994 • 298 citations

cDNA Cloning and Characterization of the Human Interleukin 13 Receptor α Chain

1996 • 285 citations

Cloning and Characterization of a Specific Interleukin (IL)-13 Binding Protein Structurally Related to the IL-5 Receptor α Chain

1996 • 278 citations

Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand.

1993 • 264 citations

A new leukemia cell line with philadelphia chromosome characterized as basophil precursors

1985 • 261 citations

IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand

1993 • 260 citations

Phenotypic Characterization of the Human Mast‐Cell Line HMC‐1

1994 • 259 citations

Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor.

1987 • 245 citations

Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells

1992 • 238 citations

An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors.

1993 • 219 citations

Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells

1992 • 203 citations

Induction of the high-affinity IgE receptor (FcɛRI) on human mast cells by IL-4

1996 • 194 citations

IL-4 and IL-13 receptors: are they one and the same?

1996 • 188 citations

The mast cell in health and disease

1990 • 170 citations

Effect of recombinant human IL-4 on tryptase, chymase, and Fc epsilon receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells.

1997 • 162 citations

Interleukin-4 Promotes the Development of Tryptase and Chymase Double-Positive Human Mast Cells Accompanied by Cell Maturation

1998 • 150 citations

Interleukin-13 Signal Transduction in Lymphohemopoietic Cells

1995 • 145 citations

Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis.

1995 • 124 citations

IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells.

1994 • 121 citations

Similarities and differences in signal transduction by interleukin 4 and interleukin 13: analysis of Janus kinase activation.

1995 • 118 citations

Signal Transduction Pathway of Interleukin-4 and Interleukin-13 in Human B Cells Derived from X-linked Severe Combined Immunodeficiency Patients

1996 • 102 citations

Presence of tumour necrosis factor or a related factor in human basophil/mast cells.

1989 • 84 citations

Interleukin-4 Induces Homotypic Aggregation of Human Mast Cells by Promoting LFA-1/ICAM-1 Adhesion Molecules

1997 • 72 citations

Soluble human high-affinity receptor for IgE abrogates the IgE-mediated allergic reaction

1993 • 71 citations

Tumor necrosis factor alpha and interleukin-1 beta mRNA expression in HMC-1 cells: differential regulation of gene product expression by recombinant interleukin-4.

1993 • 68 citations

Preferential expression of interleukin‐12 or interleukin‐4 by murine bone marrow mast cells derived in mast cell growth factor or interleukin‐3

1994 • 61 citations

Long-term generation of human mast cells in serum-free cultures of CD34+ cord blood cells stimulated with stem cell factor and interleukin- 3

1994 • 60 citations

Rat peritoneal mast cells produce IFN-gamma following IL-12 treatment but not in response to IgE-mediated activation.

1996 • 57 citations

Recombinant soluble form of the human high-affinity immunoglobulin E (IgE) receptor inhibits IgE production through its specific binding to IgE-bearing B cells.

1994 • 44 citations

Human lung mast cell activation leads to IL-13 mRNA expression and protein release.

1996 • 39 citations

Biological and Molecular Aspects of Mast Cell and Basophil Differentiation and Function

1995 • 23 citations

A comparative study of peritoneal mast cells from mutant IL-4 deficient and normal mice: evidence that IL-4 is not essential for mast cell development but enhances secretion via control of IgE binding and passive sensitization

1996 • 23 citations

Deleted Work

1955 • 0 citations