ERα Gene Expression in Human Primary Osteoblasts: Evidence for the Expression of Two Receptor Proteins

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man

1994 • 2,443 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

ERβ: Identification and characterization of a novel human estrogen receptor

1996 • 2,262 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 1,836 citations

Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

1997 • 1,808 citations

Therapeutic Approaches to Bone Diseases

2000 • 1,732 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Human Estrogen Receptor β-Gene Structure, Chromosomal Localization, and Expression Pattern1

1997 • 1,098 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Estrogen Receptors α and β Form Heterodimers on DNA

1997 • 681 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

1994 • 649 citations

Mouse Estrogen Receptor β Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor α

1997 • 610 citations

Insights from the study of animals lacking functional estrogen receptor

1994 • 587 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

1995 • 428 citations

Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERβ–/– mice

1999 • 412 citations

Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1

2000 • 405 citations

Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice

2000 • 389 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

1994 • 293 citations

Differentially Expressed Messenger RNA Isoforms of the Human Estrogen Receptor-α Gene Are Generated by Alternative Splicing and Promoter Usage

1998 • 158 citations

Expression of estrogen receptor alpha and beta during mouse embryogenesis

1999 • 140 citations

Dominant Activity of Activation Function 1 (AF-1) and Differential Stoichiometric Requirements for AF-1 and -2 in the Estrogen Receptor α-β Heterodimeric Complex

1999 • 138 citations

The limits of the cellular capacity to mediate an estrogen response.

1992 • 131 citations

Estrogen Receptor-α Is Developmentally Regulated during Osteoblast Differentiation and Contributes to Selective Responsiveness of Gene Expression

1998 • 107 citations

Biologically Active Estrogen Receptor-β: Evidence from in Vivo Autoradiographic Studies with Estrogen Receptor α-Knockout Mice

1999 • 80 citations

The limits of the cellular capacity to mediate an estrogen response

1992 • 72 citations

Tissue‐specific expression of multiple mRNA variants of the mouse estrogen receptor α gene

2000 • 60 citations

Two Functionally Different Protein Isoforms Are Produced from the Chicken Estrogen Receptor-α Gene

1999 • 51 citations

Alternative Initiation of Translation Accounts for a 67/45 kDa Dimorphism of the Human Estrogen Receptor ERα

1999 • 50 citations

Tissue selective action of tamoxifen methiodide, raloxifene and tamoxifen on creatine kinase B activity in vitro and in vivo

1996 • 50 citations

The nucleotide sequence of the chicken apo very low density lipoprotein II gene

1983 • 45 citations

Identification of Novel Chicken Estrogen Receptor-α Messenger Ribonucleic Acid Isoforms Generated by Alternative Splicing and Promoter Usage**This work was supported by the Irish American Partnership (to C.G.), the Irish Cancer Society, and an EMBO long term fellowship (to G.F.).

1998 • 24 citations

An S1 Nuclease Mapping Method for Detection of Low Abundance Transcripts

1996 • 21 citations

Tamoxifen Directly Stimulates the Mineralization of Human Osteoblast-Like Osteosarcoma Cells Through a Pathway Independent of Estrogen Response Element

1995 • 13 citations