Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13

Interleukin-13: Central Mediator of Allergic Asthma

1998 • 2,642 citations

CD4+CD25+ suppressor T cells: more questions than answers

2002 • 2,202 citations

Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

1999 • 1,475 citations

Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific

2000 • 1,282 citations

Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

1999 • 1,066 citations

Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses

2001 • 1,033 citations

CTLA-4: new insights into its biological function and use in tumor immunotherapy

2002 • 923 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

NKT cells: facts, functions and fallacies

2000 • 875 citations

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

2001 • 864 citations

The unconventional lifestyle of NKT cells

2002 • 756 citations

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

2003 • 706 citations

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

2000 • 690 citations

Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells

2002 • 639 citations

Cancer vaccines: between the idea and the reality

2003 • 616 citations

Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

2001 • 605 citations

The enemy within: keeping self-reactive T cells at bay in the periphery

2002 • 586 citations

Distinct Functional Lineages of Human Vα24 Natural Killer T Cells

2002 • 567 citations

Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance

2003 • 539 citations

Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells

1997 • 501 citations

Regulatory T cells under scrutiny

2003 • 427 citations

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor.

1996 • 406 citations

Interleukin-4 and Interleukin-13 Signaling Connections Maps

2003 • 397 citations

Prevention of Autoimmunity by Targeting a Distinct, Noninvariant CD1d-reactive T Cell Population Reactive to Sulfatide

2004 • 395 citations

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product.

1996 • 386 citations

Loss of IFN-γ Production by Invariant NK T Cells in Advanced Cancer

2001 • 370 citations

Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype.

1999 • 359 citations

A Critical Role for Natural Killer T Cells in Immunosurveillance of Methylcholanthrene-induced Sarcomas

2002 • 347 citations

Immune suppression and skin cancer development: regulation by NKT cells

2000 • 327 citations

The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1.

1998 • 324 citations

Vaccination With Irradiated Autologous Tumor Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor Augments Antitumor Immunity in Some Patients With Metastatic Non–Small-Cell Lung Carcinoma

2003 • 296 citations

Cutting Edge: Activation of NK T Cells by CD1d and α-Galactosylceramide Directs Conventional T Cells to the Acquisition of a Th2 Phenotype

1999 • 296 citations

Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens

2002 • 289 citations

Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity

2003 • 278 citations

The Murine IL-13 Receptor α2: Molecular Cloning, Characterization, and Comparison with Murine IL-13 Receptor α1

1998 • 262 citations

Immunoregulatory T cells in tumor immunity

2004 • 257 citations

Tumors as elusive targets of T-cell-based active immunotherapy

2003 • 208 citations

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product

1996 • 206 citations

Depletion of CD4+CD25+ Regulatory Cells Augments the Generation of Specific Immune T Cells in Tumor-Draining Lymph Nodes

2002 • 206 citations

Role of IL-13 in regulation of anti-tumor immunity and tumor growth

2003 • 199 citations

Antitumor and Antimetastatic Activity of IL-23

2003 • 174 citations

NKT Cells Inhibit the Onset of Diabetes by Impairing the Development of Pathogenic T Cells Specific for Pancreatic β Cells

2002 • 163 citations

Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission

2003 • 162 citations

CD4 T cells inhibit in vivo the CD8‐mediated immune response against murine colon carcinoma cells transduced with interleukin‐12 genes

1995 • 125 citations

Understanding the function of CD1-restricted T cells

2003 • 123 citations

Cytokine-secreting tumor cell vaccines

2000 • 119 citations

Resistance to Metastatic Disease in STAT6-Deficient Mice Requires Hemopoietic and Nonhemopoietic Cells and Is IFN-γ Dependent

2002 • 110 citations

Natural killer T (NKT) cells and their role in antitumor immunity

2002 • 107 citations

A push–pull approach to maximize vaccine efficacy: Abrogating suppression with an IL-13 inhibitor while augmenting help with granulocyte/macrophage colony-stimulating factor and CD40L

2002 • 91 citations

Immunization with a tumor-associated CTL epitope plus a tumor-related or unrelated Th1 helper peptide elicits protective CTL immunity

2001 • 85 citations

Immunization against endogenous retroviral tumor-associated antigens.

2001 • 82 citations

Immunosuppressive activity of cloned natural killer (NK1.1+) T cells established from murine tumor-infiltrating lymphocytes.

1997 • 70 citations

Use of cellular and cytokine adjuvants in the immunotherapy of cancer

1998 • 67 citations

Immunoregulatory T cells in cancer immunotherapy

2002 • 55 citations

A push-pull approach to maximize vaccine efficacy : abrogating suppression with an IL-13 inhibitor while augmenting help with GM-CSF and CD40L

2002 • 47 citations

Thymus and tolerance. Is regulation the major function of the thymus?

2001 • 42 citations

Absence of the CD1 Molecule Up-Regulates Antitumor Activity Induced by CpG Oligodeoxynucleotides in Mice

2002 • 31 citations

NKT Cell Defects in NOD Mice Suggest Therapeutic Opportunities

2002 • 21 citations