Effect of cyanide on nitrovasodilator-induced relaxation, cyclic GMP accumulation and guanylate cyclase activation in rat aorta

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

1977 • 1,422 citations

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

1983 • 949 citations

Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution.

1975 • 932 citations

Vascular smooth muscle. I. Normal structure, pathology, biochemistry, and biophysics.

1968 • 887 citations

Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs.

1953 • 643 citations

Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation

1983 • 623 citations

Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.

1981 • 527 citations

Sodium nitroprusside and other smooth muscle-relaxants increase cyclic GMP levels in rat ductus deferens

1977 • 422 citations

Soluble guanylate cyclase purified from bovine lung contains heme and copper

1981 • 328 citations

Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemeproteins. Evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation.

1978 • 327 citations

Regulation of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate levels and contractility in bovine tracheal smooth muscle.

1977 • 286 citations

Sodium Nitroprusside

1975 • 277 citations

Endothelium-dependent and nitrovasodilator-induced relaxation of vascular smooth muscle: role of cyclic GMP.

1983 • 264 citations

Differential effect of verapamil on excitation-contraction coupling in smooth muscle and on excitation-secretion coupling in adrenergic nerve terminals.

1972 • 260 citations

Activation of guanylate cyclase from rat liver and other tissues by sodium azide.

1975 • 228 citations

Effects of sodium nitroprusside, nitroglycerin, and sodium azide on levels of cyclic nucleotides and mechanical activity of various tissues.

1977 • 209 citations

Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme.

1982 • 182 citations

The Electrogenic NA+,K+-Pump in Smooth Muscle: Physiologic and Pharmacologic Significance

1980 • 180 citations

Mode of action of sodium nitroprusside on vascular smooth muscle

1975 • 139 citations

Nitroprusside produces cyanide poisoning via reaction with hemoglobin.

1974 • 136 citations

Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle.

1982 • 114 citations

Sodium nitroprusside-induced protein phosphorylation in intact rat aorta is mimicked by 8-bromo cyclic GMP

1982 • 113 citations

Purification and properties of heme-deficient hepatic soluble guanylate cyclase: Effects of heme and other factors on enzyme activation by NO, NO-heme, and protoporphyrin IX

1982 • 107 citations

Requirement for heme in the activation of purified guanylate cyclase by nitric oxide

1983 • 96 citations

Effects of nitroprusside and 8-bromo-cyclic GMP on the contractile activity of the rat aorta.

1983 • 94 citations

Properties and oxidative regulation of guanylate cyclase.

1977 • 83 citations

Vascular Neuroeffector Mechanisms

1975 • 80 citations

Endothelium-dependent vasodilator-and nitrovasodilator-induced relaxation may be mediated through cyclic GMP formation and cyclic GMP-dependent protein phosphorylation.

1983 • 80 citations

Enhancement of bleomycin—iron free radical damage to DNA by antioxidants and their inhibition of lipid peroxidation

1981 • 75 citations

Possible role for cyclic GMP in endothelium-dependent relaxation of rabbit aorta by acetylcholine. Comparison with nitroglycerin.

1983 • 74 citations

Effects of 2-nicotinamidoethyl nitrate on smooth muscle cells and on adrenergic transmission in the guinea-pig and porcine mesenteric arteries.

1981 • 72 citations

Vascular Smooth Muscle Relaxation by Nitro Compounds: Reduced Relaxation and cGMP Elevation in Tolerant Vessels and Reversal of Tolerance by Dithiothreitol

1982 • 63 citations

Membrane electrical properties of vascular smooth muscle from the guinea pig superior mesenteric artery

1978 • 63 citations

Differing actions of nitroprusside and D-600 on tension and 45Ca fluxes in canine renal arteries.

1979 • 63 citations

Effects of sodium nitroprusside on smooth muscle cells of rabbit pulmonary artery and portal vein.

1978 • 59 citations

Effect of nitroprusside on smooth muscle and adrenergic nerve terminals in isolated blood vessels.

1976 • 56 citations

Ba2+ and K+ alteration of K+ conductance in spontaneously active vascular muscle

1976 • 46 citations

Concentration and time-dependent relationships between isosorbide dinitrate-induced relaxation and formation of cyclic GMP in coronary arterial smooth muscle.

1983 • 42 citations

Effect of Ouabain and Alterations in Potassium Concentration on Relaxation Induced by Sodium Nitroprusside

1983 • 35 citations

Sodium nitroprusside: approaches towards the elucidation of its mode of action

1980 • 30 citations

EFFECTS OF VASODILATOR AGENTS ON SMOOTH MUSCLE CELLS OF THE CORONARY ARTERY OF THE PIG

1981 • 29 citations

Synthesis and conformations of hypothalamic hormone releasing factors: two QRF-analogues containing backbone N-methyl groups

1975 • 27 citations

Properties of purified soluble guanylate cyclase activated by nitric oxide and sodium nitroprusside.

1982 • 25 citations

Nitroprusside Increases Cyclic Guanylate Monophosphate Concentrations during Relaxation of Rabbit Aortic Strips and Both Effects Are Antagonized by Cyanide

1982 • 21 citations

Cellular basis of nitroprusside-induced relaxation of graded responses to norepinephrine and potassium in canine renal arteries.

1980 • 17 citations

The Pharmacology of Vaso-Active Antihypertensives

2015 • 15 citations

Sodium Cyanide Antagonism of the Vasodilator Action of Sodium Nitroprusside in the Isolated Rabbit Aortic Strip

1978 • 11 citations

Two Components of Laetrile (Mandelonitrile and Cyanide) Stimulate Guanylate Cyclase Activity

1979 • 7 citations

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