IgE Receptor Type I-dependent Tyrosine Phosphorylation of Phospholipid Scramblase

A receptor for phosphatidylserine-specific clearance of apoptotic cells

2000 • 1,480 citations

DIALIGN 2: improvement of the segment-to-segment approach to multiple sequence alignment.

1999 • 699 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

Lipid translocation across the plasma membrane of mammalian cells

1999 • 437 citations

Mast cells in innate immunity

2000 • 403 citations

Molecular Cloning of Human Plasma Membrane Phospholipid Scramblase

1997 • 389 citations

Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.

1993 • 369 citations

The mechanism of the calcium signal and correlation with histamine release in 2H3 cells.

1984 • 351 citations

Isolation of an Erythrocyte Membrane Protein that Mediates Ca2+-dependent Transbilayer Movement of Phospholipid

1996 • 301 citations

Regulation of Phospholipid Scramblase Activity during Apoptosis and Cell Activation by Protein Kinase Cδ

2000 • 242 citations

Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

1990 • 234 citations

Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.

1993 • 232 citations

Level of Expression of Phospholipid Scramblase Regulates Induced Movement of Phosphatidylserine to the Cell Surface

1998 • 171 citations

Isolated deficiency of platelet procoagulant activity

1979 • 165 citations

Phosphatidylserine Exposure during Apoptosis Is a Cell-Type-Specific Event and Does Not Correlate with Plasma Membrane Phospholipid Scramblase Expression

1999 • 151 citations

Identification of three new members of the phospholipid scramblase gene family

2000 • 144 citations

Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies.

1992 • 135 citations

Impaired factor X and prothrombin activation associated with decreased phospholipid exposure in platelets from a patient with a bleeding disorder

1985 • 135 citations

Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay

1999 • 131 citations

Transmembrane phospholipid distribution in blood cells: control mechanisms and pathophysiological significance.

1998 • 112 citations

Reconstitution of Phospholipid Scramblase Activity from Human Blood Platelets

1996 • 110 citations

Phosphorylation of a mast cell protein in response to treatment with anti-allergic compounds

1983 • 108 citations

Immunologic Stimulation of Mast Cells Leads to the Reversible Exposure of Phosphatidylserine in the Absence of Apoptosis

2000 • 101 citations

Scott syndrome erythrocytes contain a membrane protein capable of mediating Ca2+-dependent transbilayer migration of membrane phospholipids.

1997 • 76 citations

Aminophospholipid exposure, microvesiculation and abnormal protein tyrosine phosphorylation in the platelets of a patient with Scott syndrome: a study using physiologic agonists and local anaesthetics

1997 • 74 citations

Identity of a Conserved Motif in Phospholipid Scramblase That Is Required for Ca²⁺-Accelerated Transbilayer Movement of Membrane Phospholipids

1998 • 73 citations

Phosphorylation of the gamma chain of the high affinity receptor for immunoglobulin E by receptor-associated protein kinase C-delta.

1994 • 64 citations

Impaired Ca2+-Induced Tyrosine Phosphorylation and Defective Lipid Scrambling in Erythrocytes From a Patient With Scott Syndrome: A Study Using an Inhibitor for Scramblase That Mimics the Defect in Scott Syndrome

1998 • 53 citations

Palmitoylation of Phospholipid Scramblase Is Required for Normal Function in Promoting Ca²⁺-Activated Transbilayer Movement of Membrane Phospholipids

1998 • 51 citations

Impaired Ca2+-Induced Tyrosine Phosphorylation and Defective Lipid Scrambling in Erythrocytes From a Patient With Scott Syndrome: A Study Using an Inhibitor for Scramblase That Mimics the Defect in Scott Syndrome

1998 • 50 citations

Expression of Proteins Controlling Transbilayer Movement of Plasma Membrane Phospholipids in the B Lymphocytes From a Patient With Scott Syndrome

1998 • 47 citations

Identity of Human Normal Counterpart (MmTRA1b) of Mouse Leukemogenesis-Associated Gene (MmTRA1a) Product as Plasma Membrane Phospholipid Scramblase and Chromosome Mapping of the Human MmTRA1b/Phospholipid Scramblase Gene

1998 • 23 citations

Assessment of the Expression of Candidate Human Plasma Membrane Phospholipid Scramblase in Scott Syndrome Cells

1999 • 11 citations