Lipid-dependent recovery of alpha-bungarotoxin and monoclonal antibody binding to the purified alpha-subunit from Torpedo marmorata acetylcholine receptor. Enhancement by noncompetitive channel blockers.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Experimental and Theoretical Aspects of Protein Folding

1975 • 965 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

Use of a Snake Venom Toxin to Characterize the Cholinergic Receptor Protein

1970 • 575 citations

Primary structures of β- and δ-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences

1983 • 527 citations

The Nicotinic Cholinergic Receptor: Correlation of Molecular Structure with Functional Properties

1982 • 456 citations

Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

1980 • 452 citations

Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit.

1983 • 412 citations

Mapping of surface structures of electrophorus acetylcholine receptor using monoclonal antibodies.

1981 • 412 citations

Molecular weight in detergent solution of acetylcholine receptor from Torpedo californica

1978 • 384 citations

The Cell surface and neuronal function

1980 • 379 citations

Large‐Scale Purification of the Acetylcholine‐Receptor Protein in Its Membrane‐Bound and Detergent‐Extracted Forms from Torpedo marmorata Electric Organ

1977 • 375 citations

Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies.

1982 • 342 citations

Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments.

1981 • 332 citations

Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.

1983 • 332 citations

The acetylcholine receptor: an "allosteric" membrane protein.

1979 • 256 citations

Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata

1983 • 250 citations

Affinity-labeling of purified acetylcholine receptor from Torpedo californica

1974 • 243 citations

Myasthenia gravis induced by monoclonal antibodies to acetylcholine receptors

1980 • 201 citations

Inhibition of glycosylation with tunicamycin blocks assembly of newly synthesized acetylcholine receptor subunits in muscle cells.

1982 • 193 citations

Cholinergic receptor protein of Electrophorus electricus. II. Physical properties of the cholinergic receptor protein from Electrophorus electricus revealed by a tritiated α-toxin from Naja nigricollis venom

1972 • 158 citations

Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. II. Effect of cholinergic agonists and antagonists on the binding of the tritiated alpha-neurotoxin.

1974 • 148 citations

Demonstration of a main immunogenic region on acetylcholine receptors from human muscle using monoclonal antibodies to human receptor

1983 • 139 citations

The Affinity-Labeling of Partially Purified Acetylcholine Receptor from Electric Tissue of Electrophorus

1973 • 133 citations

Restoration of 125I-alpha-bungarotoxin binding activity to the alpha subunit of Torpedo acetylcholine receptor isolated by gel electrophoresis in sodium dodecyl sulfate.

1981 • 128 citations

Monoclonal anti-acetylcholine receptor antibodies can cause experimental myasthenia

1980 • 116 citations

Monoclonal antibodies as probes of acetylcholine receptor structure. 1. Peptide mapping

1981 • 115 citations

Binding of alpha-bungarotoxin to isolated alpha subunit of the acetylcholine receptor of Torpedo californica: quantitative analysis with protein blots.

1983 • 113 citations

Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non‐competitive blocker 5‐azido‐[³H]trimethisoquin

1980 • 111 citations

High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.

1983 • 97 citations

STRUCTURE AND FUNCTION OF THE ACETYLCHOLINE RECEPTOR MOLECULE STUDIED USING MONOCLONAL ANTIBODIES

1981 • 90 citations

Studies of reversible and irreversible interactions of an alkylating agonist with Torpedo californica acetylcholine receptor in membrane-bound and purified states

1979 • 88 citations

Multiple affinity states for noncompetitive blockers revealed by [3H]phencyclidine binding to acetylcholine receptor rich membrane fragments from Torpedo marmorata

1983 • 85 citations

Acetylcholine receptors from Torpedo and Electrophorus have similar subunit structures

1980 • 73 citations

Monoclonal antibodies directed against the neurotransmitter binding site of nicotinic acetylcholine receptor

1980 • 70 citations

Analysis of receptor-ligand interactions using nitrocellulose gel transfer: Application to Torpedo acetylcholine receptor and alpha-bungarotoxin

1983 • 54 citations

Properties of the nicotinic acetylcholine receptor macromolecule of Electrophorus electricus

1972 • 51 citations

A comparison of current‐voltage relations for full and partial agonists.

1978 • 51 citations

Interaction of monoclonal antibodies to torpedo acetylcholine receptor with the receptor of skeletal muscle

1983 • 48 citations

Monoclonal antibodies as probes of the acetylcholine receptor and myasthenia gravis

1984 • 25 citations

Restoration of calcium transport in the trypsin-treated (Ca+ + Mg2+)-dependent adenosine triphosphatase of sarcoplasmic reticulum exposed th sodium dodecyl sulfate.

1976 • 21 citations