Telomeric repeat sequences

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Animal cytology and evolution

1980 • 2,302 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

A theory of marginotomy

1973 • 1,770 citations

Origin of Concatemeric T7DNA

1972 • 1,591 citations

Animal Cytology and Evolution.

1955 • 1,258 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

Slippage synthesis of simple sequence DNA

1992 • 1,091 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

An alternative pathway for yeast telomere maintenance rescues est1− senescence

1993 • 916 citations

A mutant with a defect in telomere elongation leads to senescence in yeast

1989 • 905 citations

Conservation of the human telomere sequence (TTAGGG)n among vertebrates.

1989 • 809 citations

Loss of a yeast telomere: Arrest, recovery, and chromosome loss

1993 • 787 citations

Isolation of a higher eukaryotic telomere from Arabidopsis thaliana

1988 • 686 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

1990 • 614 citations

STRUCTURE AND FUNCTION OF TELOMERES

1989 • 604 citations

TELOMERASES

1992 • 531 citations

Transposons in place of telomeric repeats at a Drosophila telomere

1993 • 436 citations

The remaking of chromosomes

1938 • 416 citations

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

1990 • 288 citations

Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid.

1993 • 254 citations

The β subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA

1993 • 249 citations

Human telomeres: fusion and interstitial sites

1989 • 248 citations

Addition of telomere-associated HeT DNA sequences “heals” broken chromosome ends in Drosophila

1990 • 245 citations

Instability of simple sequence DNA in Saccharomyces cerevisiae.

1992 • 240 citations

Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells.

1990 • 222 citations

Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase

1991 • 205 citations

Developmentally programmed healing of chromosomes by telomerase in tetrahymena

1991 • 204 citations

Functional reintroduction of human telomeres into mammalian cells.

1991 • 186 citations

Identification of a Pentanucleotide Telomeric Sequence, (TTAGG)_n, in the Silkworm Bombyx mori and in Other Insects

1993 • 183 citations

Large deletions result from breakage and healing of P. falciparum chromosomes

1988 • 180 citations

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats.

1993 • 177 citations

The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae.

1992 • 171 citations

Recombination occurs during telomere formation in yeast

1989 • 169 citations

Identification of a pentanucleotide telomeric sequence, (TTAGG)n, in the silkworm Bombyx mori and in other insects.

1993 • 164 citations

The fusion of broken ends of sister half-chromatids following chromatid breakage at meiotic anaphases

1938 • 152 citations

Viable deletions of a telomere from a Drosophila chromosome

1989 • 151 citations

The centromere of budding yeast

1993 • 149 citations

Telomere telomere recombination provides an express pathway for telomere acquisition

1990 • 146 citations

Frequent transpositions of Drosophila melanogaster HeT-A transposable elements to receding chromosome ends.

1992 • 144 citations

Telomere directed fragmentation of mammalian chromosomes

1993 • 140 citations

Chromosome ends in Drosophila without telomeric DNA sequences.

1990 • 139 citations

New telomere formation after developmentally regulated chromosomal breakage during the process of chromatin diminution in ascaris lumbricoides

1991 • 130 citations

Genetics and Molecular Biology of Telomeres

1992 • 128 citations

Interstitial localization of telomeric DNA sequences in the Indian muntjac chromosomes: further evidence for tandem chromosome fusions in the karyotypic evolution of the Asian muntjacs

1993 • 126 citations

The centromere region ofArabidopsis thalianachromosome 1 contains telomere-similar sequences

1991 • 125 citations

Developmentally controlled telomere addition in wild-type and mutant paramecia.

1988 • 124 citations

The presence of interstitial telomeric sequences in constitutional chromosome abnormalities.

1992 • 122 citations

Physical mapping of the human pseudo-autosomal region; comparison with genetic linkage map.

1988 • 120 citations

Telomere–associated chromosome fragmentation: applications in genome manipulation and analysis

1992 • 117 citations

Characterization of a G-quartet formation reaction promoted by the .beta.-subunit of the Oxytricha telomere-binding protein

1993 • 117 citations

Progressive loss of DNA sequences from terminal chromosome deficiencies in Drosophila melanogaster.

1988 • 116 citations

The human minisatellite consensus at breakpoints of oncogene translocations

1990 • 111 citations

A “hot spot” of recombination coincides with an interstitial telomeric sequence in the Armenian hamster

1993 • 108 citations

Aneuploidy. Part A: Incidence and etiology.

1987 • 101 citations

Mobile elements bounded by C4A4 telomeric repeats in oxytricha fallax

1985 • 99 citations

The internally located telomeric sequences in the germ-line chromosomes of tetrahymena are at the ends of transposon-like elements

1985 • 97 citations

Autonomous replication and addition of telomerelike sequences to DNA microinjected into Paramecium tetraurelia macronuclei.

1988 • 95 citations

Unusually large telomeric repeats in the yeast Candida albicans.

1993 • 94 citations

mu-2: mutator gene in Drosophila that potentiates the induction of terminal deficiencies.

1984 • 88 citations

Cloning and characterization of chromosome breakpoints ofPlasmodium falciparum: breakage and new telomere formation occurs frequently and randomly in subtelomeric genes

1992 • 85 citations

Targeted breakage of a human chromosome mediated by cloned human telomeric DNA

1992 • 80 citations

Characterization of Two Telomeric DNA Processing Reactions in Saccharomyces cerevisiae

1988 • 79 citations

Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe.

1987 • 79 citations

Characterization of chromosome fragmentation in two protozoans and identification of a candidate fragmentation sequence in Euplotes crassus.

1989 • 77 citations

Expression of the RESA gene in Plasmodium falciparum isolate FCR3 is prevented by a subtelomeric deletion.

1989 • 75 citations

Murine radiation myeloid leukaemogenesis: Relationship between interstitial telomere‐like sequences and chromosome 2 fragile sites

1993 • 73 citations

Telomeric site position heterogeneity in macronuclear DNA ofParamecium primaurelia

1987 • 72 citations

Telomere-related sequences at interstitial sites in the human genome

1990 • 65 citations

Interstitial hybridization sites of the (TTAGGG)<sub>n</sub> telomeric sequence on the chromosomes of some North American hylid frogs

1992 • 63 citations

Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break.

1993 • 62 citations

Instability of Simple Sequence DNA in Saccharomyces cerevisiae

1992 • 61 citations

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)_n

1990 • 53 citations

Interstitial telomeres are hotspots for illegitimate recombination with DNA molecules injected into the macronucleus of Paramecium primaurelia.

1992 • 53 citations

Precise excision of telomere-bearing transposons during Oxytricha fallax macronuclear development.

1989 • 52 citations

Localization of the repetitive telomeric sequence (TTAGGG)<sub>n</sub> in two muntjac species and implications for their karyotypic evolution

1990 • 50 citations

Characterization of two telomeric DNA processing reactions in Saccharomyces cerevisiae.

1988 • 50 citations

The Pseudoautosomal Region of the Human Sex Chromosomes

1986 • 48 citations

Molecular characterization of a pericentric inversion in mouse chromosome 8 implicates telomeres as promoters of meiotic recombination

1993 • 47 citations

23 The Genomic Tag Hypothesis: Modern Viruses as Molecular Fossils of Ancient Strategies for Genomic Replication

1993 • 47 citations

Eukaryotic nuclear telomeres: Molecular fossils of the RNP world?

1988 • 46 citations

Developmentally Controlled Telomere Addition in Wild-Type and Mutant Paramecia

1988 • 46 citations

A repetitive DNA element, associated with telomeric sequences in Drosophila melanogaster, contains open reading frames

1992 • 42 citations

Leukemia characterized by multiple sub‐clones with unbalanced translocations involving different telomeric segments: Case report and review of the literature

1990 • 40 citations

Telomeres inhibit end to end fusion and enhance maintenance of linear DNA molecules injected into theParamecium primaureliamacronucleus

1991 • 39 citations

Telomeric signals in Robertsonian fusion and fission chromosomes: implications for the origin of pseudoaneuploidy

1992 • 38 citations

Repetitive DNA sequences located in the terminal portion of theCaenorhabditis eleganschromosomes

1993 • 33 citations

The role of DNA repeats and associated secondary structures in genomic instability and neoplasia

1993 • 31 citations

G-quartets in biology: reprise.

1993 • 31 citations

Identification of Healed Terminal DNA Fragments in Linear Minichromosomes of Schizosaccharomyces pombe

1987 • 30 citations

Unusually Large Telomeric Repeats in the Yeast Candida albicans

1993 • 27 citations

Autonomous Replication and Addition of Telomerelike Sequences to DNA Microinjected into Paramecium tetraurelia Macronuclei

1988 • 26 citations

FRA2B is distinct from inverted telomere repeat arrays at 2q13

1992 • 22 citations

Drosophila melanogaster does not share the telomeric repeat sequence of another invertebrate, Ascaris lumbricoides

1993 • 21 citations

Telomere-like DNA polymorphisms associated with genetic predisposition to acute myeloid leukemia in irradiated CBA mice.

1993 • 19 citations

Acquisition of Telomere Repeat Sequences by Transfected DNA Integrated at the Site of a Chromosome Break

1993 • 17 citations

Sequence characterization ofTetrahymenamacronuclear DNA ends

1986 • 17 citations

The organization of internal telomeric repeats in the polytene chromosomes of the hypotrichous ciliateStylonychia lemnae

1993 • 15 citations

Expression of the RESA Gene in Plasmodium falciparum Isolate FCR3 Is Prevented by a Subtelomeric Deletion

1989 • 15 citations

Transposition as a Mechanism for Maintaining Telomere Length in Drosophila

1993 • 6 citations