Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, and P38 kinase

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

1996 • 1,519 citations

MAPKs: new JNK expands the group

1994 • 949 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal

1993 • 646 citations

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

1995 • 578 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

Biochemistry and physiology of the skin

1983 • 487 citations

Role of p38 and JNK Mitogen-Activated Protein Kinases in the Activation of Ternary Complex Factors

1997 • 467 citations

The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase.

1996 • 419 citations

Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.

1994 • 377 citations

Three distinct signalling responses by murine fibroblasts to genotoxic stress

1996 • 359 citations

Polypeptide signaling for plant defensive genes exhibits analogies to defense signaling in animals.

1996 • 349 citations

The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.

1996 • 338 citations

UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.

1993 • 262 citations

The proliferation of MAP kinase signaling pathways in yeast

1995 • 243 citations

The octadecanoid signalling pathway in plants mediates a response to ultraviolet radiation

1996 • 242 citations

Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

1997 • 226 citations

The UV response involving the ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals

1994 • 225 citations

Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid

1997 • 213 citations

Proteinase inhibitor II from potatoes: isolation and characterization of its protomer components

1976 • 177 citations

Inhibition of Activator Protein 1 Activity and Neoplastic Transformation by Aspirin

1997 • 174 citations

Chymotrypsin Inhibitor I from Potatoes

1972 • 172 citations

The Carcinogenic Effect of UVA Irradiation

1983 • 166 citations

Requirement for Phosphatidylinositol 3-Kinase in Epidermal Growth Factor-Induced AP-1 Transactivation and Transformation in JB6 P⁺ Cells

1996 • 150 citations

Photocarcinogenesis by Near-Ultraviolet (UVA) Radiation in Sencar Mice

1986 • 130 citations

OXYGEN‐DEPENDENCE OF NEAR UV (365 NM) LETHALITY AND THE INTERACTION OF NEAR UV AND X‐RAYS IN TWO MAMMALIAN CELL LINES

1976 • 123 citations

Ultraviolet B-induced Activated Protein-1 Activation Does Not Require Epidermal Growth Factor Receptor but Is Blocked by a Dominant Negative PKCλ/ι

1996 • 116 citations

Chymotrypsin-specific protease inhibitors decrease H₂O₂ formation by activated human polymorphonuclear leukocytes

1987 • 84 citations

Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors

1995 • 83 citations

Anticarcinogenic Activity of Protease Inhibitors Overview

1993 • 61 citations

Dosage‐dependent dominance over wild‐type p53 of a mutant p53 isolated from nasopharyngeal carcinoma ¹

1993 • 54 citations

Okadaic acid induces the expression of both early and secondary response genes in mouse keratinocytes

1992 • 41 citations

Signal transduction through atypical PKCs, but not the EGF receptor, is necessary for UVC-induced AP-1 activation in immortal murine cells

1997 • 39 citations

Identification of a UV-induced trans-acting protein that stimulates polyomavirus DNA replication

1988 • 39 citations

Inhibition of radiation-induced transformation of C3H/10T½ cells by chymotrypsin inhibitor 1 from potatoes

1987 • 33 citations

Effects Of Solar Radiation On The Skin

1993 • 31 citations

UV-Induced DNA Damage Is an Intermediate Step in UV-Induced Expression of Human Immunodeficiency Virus Type 1, Collagenase, c-fos, and Metallothionein

1989 • 31 citations

Inhibition of radiation-induced transformation of C3H/10T1/2 cells by carboxypeptidase inhibitor 1 and inhibitor II from potatoes

1989 • 30 citations

Inhibitory effects of ascorbic acid on AP-1 activity and transformation of JB6 cells

1996 • 21 citations