Effect of a novel selective and potent phosphinic peptide inhibitor of endopeptidase 3.4.24.16 on neurotensin‐induced analgesia and neuronal inactivation

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1995 • 1,887 citations

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

1995 • 1,800 citations

Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines.

1953 • 1,702 citations

Neurotensin: Antinocisponsive action in rodents

1979 • 230 citations

Are there neuropeptide-specific peptidases?

1985 • 197 citations

Degradation of Neurotensin by Rat Brain Synaptic Membranes: Involvement of a Thermolysin‐Like Metalloendopeptidase (Enkephalinase), Angiotensin‐Converting Enzyme, and Other Unidentified Peptidases

1983 • 153 citations

Purification and characterization of a novel neurotensin-degrading peptidase from rat brain synaptic membranes.

1986 • 139 citations

Inactivation and Metabolism of Neuropeptides

1986 • 117 citations

Nociceptin/Orphanin FQ Metabolism: Role of Aminopeptidase and Endopeptidase 24.15

1997 • 113 citations

Neurotensin modulates dopamine neurotransmission at several levels along brain dopaminergic pathways

1989 • 104 citations

Neurotensin: central nervous system effects of a neuropeptide

1980 • 96 citations

Development of the First Potent and Selective Inhibitor of the Zinc Endopeptidase Neurolysin Using a Systematic Approach Based on Combinatorial Chemistry of Phosphinic Peptides

1996 • 91 citations

Endopeptidases 24.16 and 24.15 Are Responsible for the Degradation of Somatostatin, Neurotensin, and Other Neuropeptides by Cultivated Rat Cortical Astrocytes

1994 • 84 citations

Protection of the Hydroxyphosphinyl Function of Phosphinic Dipeptides by Adamantyl. Application to the Solid-Phase Synthesis of Phosphinic Peptides

1996 • 80 citations

Neuropeptide Function in the Gastrointestinal Tract

2019 • 76 citations

Distinct Properties of Neuronal and Astrocytic Endopeptidase 3.4.24.16: A Study on Differentiation, Subcellular Distribution, and Secretion Processes

1996 • 70 citations

A simple method for the determination of angiotensin I converting enzyme

1968 • 69 citations

Potentiation by thiorphan and bestatin of the naloxone-insensitive analgesic effects of neurotensin and neuromedin n

1988 • 64 citations

Specific inhibition of endopeptidase 24.16 by dipeptides

1991 • 62 citations

Methods in neurotransmitter and neuropeptide research

1993 • 56 citations

Neurotensin metabolism in various tissues of central and peripheral origins: ubiquitous involvement of a novel neurotensin degrading metalloendopeptidase

1988 • 54 citations

High-Affinity Receptor Sites and Rapid Proteolytic Inactivation of Neurotensin in Primary Cultured Neurons

1986 • 47 citations

Analgesic responses elecited by endogenous enkephalins (protected by mixed peptidase inhibitors) in a variety of morphine-sensitive noxious tests

1991 • 45 citations

Role of endopeptidase 3.4.24.16 in the catabolism of neurotensin, in vivo, in the vascularly perfused dog ileum

1994 • 44 citations

Neuropeptides and their peptidases: Functional considerations

1988 • 43 citations

Colocalization of neurotensin receptors and of the neurotensin- degrading enzyme endopeptidase 24-16 in primary cultures of neurons

1990 • 38 citations

Phosphorus‐containing peptides as mixed inhibitors of endopeptidase 3.4.24.15 and 3.4.24.16: effect on neurotensin degradation in vitro and in vivo

1995 • 33 citations

Fluorimetric assay of the neurotensin-degrading metalloendopeptidase, endopeptidase 24.16

1991 • 30 citations

Naloxone-insensitive potentiation of neurotensin hypothermic effect by the enkephalinase inhibitor thiorphan

1986 • 28 citations

Potent inhibition of endopeptidase 24.16 and endopeptidase 24.15 by the phosphonamide peptide N-(phenylethylphosphonyl)-Gly-<scp>l</scp>-Pro-<scp>l</scp>-aminohexanoic acid

1992 • 28 citations

Tissue distribution of a novel neurotensin-degrading metallopeptidase. An immunological approach using monospecific polyclonal antibodies

1989 • 26 citations

Specificity of Neurotensin Metabolism by Regional Rat Brain Slices

1992 • 20 citations

Effects of thiorphan, bestatin and a novel metallopeptidase inhibitor JMV 390-1 on the recovery of neurotensin and neuromedin N released from mouse hypothalamus

1992 • 20 citations

Neurotensin and neuromedin N undergo distinct catabolic processes in murine astrocytes and primary cultured neurons

1994 • 17 citations

Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat brain slices.

1994 • 13 citations

Deleted Work

1955 • 0 citations