Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

1990 • 775 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

1988 • 618 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Transgenic mice harboring SV40 t-antigen genes develop characteristic brain tumors

1984 • 492 citations

Exact prediction of a natural T cell epitope

1991 • 455 citations

Cell Biology of Antigen Processing and Presentation to Major Histocompatibility Complex Class I Molecule-Restricted T Lymphocytes

1992 • 373 citations

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule

1992 • 344 citations

Brefeldin A Specifically Inhibits Presentation of Protein Antigens to Cytotoxic T Lymphocytes

1989 • 329 citations

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1992 • 322 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

Role of self-peptides in positively selecting the T-cell repertoire

1990 • 300 citations

Defective Presentation of Endogenous Antigen by a Cell Line Expressing Class I Molecules

1990 • 202 citations

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors.

1986 • 188 citations

The T-cell repertoire for antigen and MHC

1988 • 180 citations

A novel MHC class II epitope expressed in thymic medulla but not cortex

1989 • 175 citations

Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

1990 • 170 citations

Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations

1980 • 125 citations

The effects of MHC gene dosage and allelic variation on T cell receptor selection

1990 • 123 citations

Medullary but not cortical thymic epithelial cells present soluble antigens to helper T cells.

1992 • 98 citations

Restricted helper function of F1 leads to parent bone marrow chimeras controlled by K-end of H-2 complex.

1978 • 96 citations

The effect of mutations in the MHC class I peptide binding groove on the cytotoxic T lymphocyte recognition of the K^b‐restricted ovalbumin determinant

1990 • 86 citations

Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium

1989 • 83 citations

Single-residue changes in class I major histocompatibility complex molecules stimulate responses to self peptides.

1992 • 43 citations

Pillars article: the major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.

2006 • 19 citations

Stop and go in the thymus

1988 • 14 citations