Transgenic mice harboring SV40 t-antigen genes develop characteristic brain tumors

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

1981 • 795 citations

Translocations Among Antibody Genes in Human Cancer

1983 • 736 citations

Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

1983 • 699 citations

Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs

1981 • 681 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1982 • 630 citations

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas

1982 • 624 citations

Cellular Transforming Genes

1982 • 622 citations

DNA Tumor Viruses

1982 • 550 citations

De novo methylation and expression of retroviral genomes during mouse embryogenesis

1982 • 524 citations

Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus.

1976 • 491 citations

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1983 • 485 citations

Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

1981 • 475 citations

Human-tumor-derived cell lines contain common and different transforming genes

1981 • 455 citations

Function of simian virus 40 gene A in transforming infection

1975 • 447 citations

Simian Virus 40 DNA Sequences in DNA of Healthy Adult Mice Derived from Preimplantation Blastocysts Injected with Viral DNA

1974 • 436 citations

A practical approach for quantitating specific mRNAs by solution hybridization

1983 • 427 citations

Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring

1982 • 379 citations

Transforming activity of human tumor DNAs.

1981 • 374 citations

Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53.

1983 • 313 citations

The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

1981 • 285 citations

Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells

1978 • 284 citations

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.

1982 • 268 citations

Identification of the oncogenic substance in rhesus monkey kidney cell cultures as simian virus 40

1962 • 246 citations

A foreign β-globin gene in transgenic mice: Integration at abnormal chromosomal positions and expression in inappropriate tissues

1983 • 245 citations

Independent mechanisms involved in suppression of the moloney leukemia virus genome during differentiation of murine teratocarcinoma cells

1983 • 205 citations

Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

1983 • 202 citations

The induction of ovalbumin and conalbumin mRNA by estrogen and progesterone in chick oviduct explant cultures

1978 • 200 citations

CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS

1965 • 198 citations

Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal

1981 • 179 citations

The SV40 a gene product is required for the production of a 54,000 MW cellular tumor antigen

1979 • 179 citations

Neoplastic differentiation: Interaction of simian virus 40 and polyoma virus with murine teratocarcinoma cells in vitro

1975 • 179 citations

Recovery of DNA segments from agarose gels

1980 • 157 citations

Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells.

1982 • 130 citations

Expression of the chicken transferrin gene in transgenic mice

1983 • 126 citations

Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

1983 • 104 citations

Leukemia, Lymphoma, and Osteosarcoma Induced in the Syrian Golden Hamster by Simian Virus 40

1972 • 104 citations

Evidence for non-spliced SV40 RNA in undifferentiated murine teratocarcinoma stem cells

1979 • 98 citations

Methylation of the viral genome in an in vitro model of herpes simplex virus latency.

1982 • 88 citations

Tumor induction by simian virus 40 in mice is controlled by long-term persistence of the viral genome and the immune response of the host

1984 • 34 citations

Sarcomas Induced by Injection of Simian Virus 40 Into Neonatal CFW Mice<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1979 • 16 citations

Incidence, Latency, and Morphologic Types of Neoplasms Induced by Simian Virus 40 Inoculated Intravenously Into Hamsters of Three Inbred Strains and One Outbred Stock2

1978 • 8 citations

Tumorigenicity of Polyoma Virus in Hamsters

1980 • 8 citations