Discovery and utilization of haplotypes for pharmacogenetic studies of psychotropic drug response

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome

1998 • 2,163 citations

Complex promoter and coding region β ₂ -adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

2000 • 971 citations

Haplotype Variation and Linkage Disequilibrium in 313 Human Genes

2001 • 879 citations

Neuropsychopharmacology

2004 • 652 citations

Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome

1998 • 506 citations

Haplotype Structure and Population Genetic Inferences from Nucleotide-Sequence Variation in Human Lipoprotein Lipase

1998 • 439 citations

Archaic African and Asian lineages in the genetic ancestry of modern humans.

1997 • 415 citations

Is the most frequent allele the oldest?

1977 • 275 citations

Neuroleptic-Induced Decrease in Plasma Homovanillic Acid and Antipsychotic Activity in Schizophrenic Patients

1984 • 244 citations

A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia

2000 • 169 citations

Patterns of Ancestral Human Diversity: An Analysis of Alu-Insertion and Restriction-Site Polymorphisms

2001 • 167 citations

Plasma catecholamine metabolites and early response to haloperidol.

1984 • 146 citations

Genetic polymorphisms for drug metabolism (CYP2D6) and tardive dyskinesia in schizophrenia

1998 • 126 citations

Benefits and pitfalls encountered in psychiatric genetic association studies

1999 • 97 citations

Non-functional CYP2D6 alleles and risk for neuroleptic-induced movement disorders in schizophrenic patients

1997 • 97 citations

Pharmacogenetics of antipsychotic treatment: lessons learned from clozapine

2000 • 94 citations

Tardive dyskinesia and debrisoquine 4-hydroxylase (CYP2D6) genotype in Japanese schizophrenics

1998 • 77 citations

Serotonin function and treatment response to clozapine in schizophrenic patients

1993 • 68 citations

Effects of clozapine and thiothixene on glucose metabolic rate in schizophrenia.

1992 • 62 citations

Locating Regions of Differential Variability in DNA and Protein Sequences

1999 • 47 citations

Nucleotide sequence diversity in non-coding regions of ALDH2 as revealed by restriction enzyme and SSCP analysis

1999 • 43 citations

Pharmacogenetic assessment of antipsychotic-induced movement disorders: contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes

2001 • 33 citations

Clozapine effects on neuroendocrine response to apomorphine challenge testing in chronic neuroleptic nonresponsive schizophrenia: Preliminary findings

1995 • 12 citations

Biologic Predictors of Clozapine Response in Schizophrenia

1996 • 4 citations