Blockade of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

1988 • 1,202 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death

1984 • 893 citations

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

1971 • 808 citations

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

1987 • 647 citations

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

1990 • 589 citations

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

1988 • 517 citations

Neurotoxicity of excitatory amino acids

1990 • 466 citations

Neurotoxicity ofN-methyl-d-aspartate is markedly enhanced in developing rat central nervous system

1988 • 465 citations

GLUTAMATE-INDUCED NEURONAL NECROSIS IN THE INFANT MOUSE HYPOTHALAMUS

1971 • 409 citations

GLUTAMATE—INDUCED RETINAL DEGENERATION IN NEONATAL MICE. ELECTRON MICROSCOPY OF THE ACUTELY EVOLVING LESION

1969 • 352 citations

Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity

1989 • 337 citations

The role of specific ions in glutamate neurotoxicity

1986 • 298 citations

Non-NMDA receptor-mediated neurotoxicity in cortical culture

1990 • 291 citations

The Calcium Channel Blocker Nifedipine Attenuates Slow Excitatory Amino Acid Neurotoxicity

1990 • 271 citations

MK-801 protects the neonatal brain from hypoxic-ischemic damage

1987 • 261 citations

Glutamate Antagonist Therapy Reduces Neurologic Deficits Produced by Focal Central Nervous System Ischemia

1988 • 245 citations

Focal Cerebral Ischaemia in the Cat: Treatment with the Glutamate Antagonist MK-801 after Induction of Ischaemia

1988 • 244 citations

Ontogenetic development of kainate neurotoxicity: correlates with glutamatergic innervation.

1978 • 236 citations

MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain

1989 • 161 citations

The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics

1986 • 147 citations

MK-801 powerfully protects against N-methyl aspartate neurotoxicity

1987 • 141 citations

Photothrombosis-induced ischemic neuronal degeneration in the rat retina

1989 • 72 citations

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