Molecular tools to elucidate problems in excitation-contraction coupling

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence

1985 • 1,126 citations

Purification and reconstitution of the calcium release channel from skeletal muscle

1988 • 928 citations

Purification and Properties of an Adenosine Triphosphatase from Sarcoplasmic Reticulum

1970 • 835 citations

Two Ca2+ ATPase genes: Homologies and mechanistic implications of deduced amino acid sequences

1986 • 812 citations

Control of muscle contraction

1969 • 785 citations

Structural evidence for direct interaction between the molecular components of the transverse tubule/sarcoplasmic reticulum junction in skeletal muscle.

1988 • 768 citations

Energy Interconversion by the Ca2+-Dependent ATPase of the Sarcoplasmic Reticulum

1979 • 718 citations

ADENOSINE TRIPHOSPHATE-LINKED CONCENTRATION OF CALCIUM IONS IN A PARTICULATE FRACTION OF RABBIT MUSCLE

1962 • 701 citations

Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum.

1990 • 644 citations

Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum.

1990 • 617 citations

Purification of the ryanodine receptor and identity with feet structures of junctional terminal cisternae of sarcoplasmic reticulum from fast skeletal muscle.

1987 • 607 citations

Location of high affinity Ca2 +-binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca2+-ATPase

1989 • 569 citations

Isolation of a Calcium-Sequestering Protein from Sarcoplasmic Reticulum

1971 • 552 citations

Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia

1990 • 508 citations

Purified ryanodine receptor from skeletal muscle sarcoplasmic reticulum is the Ca2+-permeable pore of the calcium release channel.

1987 • 503 citations

Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum.

1988 • 475 citations

Mechanism of Calcium Transport

1985 • 453 citations

Molecular cloning of the high affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum

1989 • 417 citations

STUDIES OF THE TRIAD

1970 • 413 citations

Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases.

1988 • 379 citations

Sarcoplasmic reticulum contains adenine nucleotide-activated calcium channels

1985 • 378 citations

METABOLIC ERROR OF MUSCLE METABOLISM AFTER RECOVERY FROM MALIGNANT HYPERTHERMIA

1970 • 318 citations

Mutation of aspartic acid-351, lysine-352, and lysine-515 alters the Ca2+ transport activity of the Ca2+-ATPase expressed in COS-1 cells.

1988 • 298 citations

Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum

1989 • 297 citations

Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia.

1988 • 238 citations

Amino acid sequence of rabbit fast-twitch skeletal muscle calsequestrin deduced from cDNA and peptide sequencing.

1987 • 236 citations

Identification and characterization of the high affinity [3H]ryanodine receptor of the junctional sarcoplasmic reticulum Ca2+ release channel.

1987 • 229 citations

Purified ryanodine receptor of skeletal muscle sarcoplasmic reticulum forms Ca2+-activated oligomeric Ca2+ channels in planar bilayers.

1988 • 213 citations

The predicted secondary structures of the nucleotide‐binding sites of six cation‐transporting ATPases lead to a probable tertiary fold

1989 • 163 citations

Functional consequences of alterations to polar amino acids located in the transmembrane domain of the Ca2(+)-ATPase of sarcoplasmic reticulum.

1990 • 160 citations

Three-dimensional crystals of CaATPase from sarcoplasmic reticulum. Symmetry and molecular packing

1990 • 158 citations

Subunit structure of junctional feet in triads of skeletal muscle: a freeze-drying, rotary-shadowing study.

1984 • 158 citations

Functional Consequences of Proline Mutations in the Cytoplasmic and Transmembrane Sectors of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 157 citations

Sequential mechanism of calcium binding and translocation in sarcoplasmic reticulum adenosine triphosphatase.

1987 • 152 citations

Functional Consequences of Glutamate, Aspartate, Glutamine, and Asparagine Mutations in the Stalk Sector of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 151 citations

A calmodulin-dependent protein kinase system from skeletal muscle sarcoplasmic reticulum. Phosphorylation of a 60,000-dalton protein.

1982 • 129 citations

Functional Consequences of Mutations in the β-Strand Sector of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 125 citations

Expression and Site-specific Mutagenesis of Phospholamban

1989 • 123 citations

Functional Consequences of Alterations to Amino Acids Located in the Catalytic Center (Isoleucine 348 to Threonine 357) and Nucleotide-binding Domain of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 120 citations

Purification and characterization of the 53,000-dalton glycoprotein from the sarcoplasmic reticulum.

1981 • 116 citations

Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs

1988 • 109 citations

Evidence for a junctional feet-ryanodine receptor complex from sarcoplasmic reticulum

1987 • 99 citations

Monoclonal antibodies to the Ca2+ + Mg2+-dependent ATPase of sarcoplasmic reticulum identify polymorphic forms of the enzyme and indicate the presence in the enzyme of a classical high-affinity Ca2+ binding site

1984 • 98 citations

Porcine malignant hyperthermia carrier detection and chromosomal assignment using a linked probe

1988 • 94 citations

Isolation, characterization, and localization of the spanning protein from skeletal muscle triads.

1986 • 91 citations

Functional consequences of mutations of conserved amino acids in the beta-strand domain of the Ca2(+)-ATPase of sarcoplasmic reticulum.

1990 • 84 citations

Distances between the functional sites of the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum.

1985 • 82 citations

Molecular cloning and expression of cDNA encoding a lumenal calcium binding glycoprotein from sarcoplasmic reticulum.

1989 • 79 citations

The human ryanodine receptor gene: its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy.

1990 • 77 citations

Simple model for the chemical potential change of a transported ion in active transport.

1982 • 73 citations

Molecular Cloning and Expression of cDNA Encoding the 53,000-Dalton Glycoprotein of Rabbit Skeletal Muscle Sarcoplasmic Reticulum

1989 • 64 citations

Identification of a constituent of the junctional feet linking terminal cisternae to transverse tubules in skeletal muscle.

1982 • 56 citations

Occlusion of calcium in the ADP-sensitive phosphoenzyme of the adenosine triphosphatase of sarcoplasmic reticulum.

1983 • 56 citations

Electron microscope observations on Ca2+-ATPase microcrystals in detergent-solubilized sarcoplasmic reticulum.

1988 • 50 citations

Evidence for the cytoplasmic location of the N- and C-terminal segments of sarcoplasmic reticulum (Ca2+Mg2+)-ATPase

1989 • 46 citations

Distinct immunopeptide maps of the sarcoplasmic reticulum Ca2+ release channel in malignant hyperthermia.

1990 • 45 citations

Distances between the functional sites of sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPase and the lipid/water interface

1986 • 34 citations

Isolation of the calmodulin‐dependent protein kinase system from rabbit skeletal muscle sarcoplasmic reticulum

1988 • 25 citations

Malignant hyperthermia susceptibility: biochemical basis for pathogenesis and diagnosis.

1990 • 22 citations

Distances between functional sites in cardiac sarcoplasmic reticulum (Ca²⁺+ Mg²⁺)‐ATPase

1988 • 14 citations