Functional consequences of mutations of conserved amino acids in the beta-strand domain of the Ca2(+)-ATPase of sarcoplasmic reticulum.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence

1985 • 1,126 citations

Purification and Properties of an Adenosine Triphosphatase from Sarcoplasmic Reticulum

1970 • 835 citations

Two Ca2+ ATPase genes: Homologies and mechanistic implications of deduced amino acid sequences

1986 • 812 citations

Control of muscle contraction

1969 • 785 citations

Energy Interconversion by the Ca2+-Dependent ATPase of the Sarcoplasmic Reticulum

1979 • 718 citations

Location of high affinity Ca2 +-binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca2+-ATPase

1989 • 569 citations

Structure and function of proton translocating ATPase in plasma membranes of plants and fungi

1988 • 464 citations

INTRACELLULAR PROTEASES

1987 • 460 citations

Mechanism of Calcium Transport

1985 • 453 citations

Cooperative calcium binding and ATPase activation in sarcoplasmic reticulum vesicles.

1980 • 384 citations

Mutation of aspartic acid-351, lysine-352, and lysine-515 alters the Ca2+ transport activity of the Ca2+-ATPase expressed in COS-1 cells.

1988 • 298 citations

Phosphorylation of the sarcoplasmic reticulum membrane by orthophosphate. Inhibition by calcium ions

1973 • 243 citations

Structure and Function of the Calcium Pump Protein of Sarcoplasmic Reticulum

1982 • 196 citations

Functional consequences of alterations to polar amino acids located in the transmembrane domain of the Ca2(+)-ATPase of sarcoplasmic reticulum.

1990 • 160 citations

Functional Consequences of Proline Mutations in the Cytoplasmic and Transmembrane Sectors of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 157 citations

Functional Consequences of Glutamate, Aspartate, Glutamine, and Asparagine Mutations in the Stalk Sector of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 151 citations

Functional Consequences of Mutations in the β-Strand Sector of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 125 citations

Functional Consequences of Alterations to Amino Acids Located in the Catalytic Center (Isoleucine 348 to Threonine 357) and Nucleotide-binding Domain of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 120 citations

Dissection of functional domains of the yeast proton-pumping ATPase by directed mutagenesis.

1988 • 112 citations

Changes in Ca2+ affinity related to conformational transitions in the phosphorylated state of soluble monomeric Ca2+-ATPase from sarcoplasmic reticulum.

1985 • 104 citations

Monoclonal antibodies to the Ca2+ + Mg2+-dependent ATPase of sarcoplasmic reticulum identify polymorphic forms of the enzyme and indicate the presence in the enzyme of a classical high-affinity Ca2+ binding site

1984 • 98 citations

Phosphorylation of the sarcoplasmic reticulum membrane by orthophosphate through two different reactions

1974 • 87 citations

Sequential dissociation of calcium from the calcium adenosinetriphosphatase of sarcoplasmic reticulum and the calcium requirement for its phosphorylation by ATP

1988 • 84 citations

Ca2+-ATPase membrane crystals in sarcoplasmic reticulum. The effect of trypsin digestion.

1983 • 83 citations

Ca2(+)-induced conformational changes and location of Ca2+ transport sites in sarcoplasmic reticulum Ca2(+)-ATPase as detected by the use of proteolytic enzyme (V8).

1990 • 67 citations

Structure and Function of Sarcoplasmic Reticulum

1986 • 60 citations

Effect of divalent cation bound to the ATPase of sarcoplasmic reticulum. Activation of phosphoenzyme hydrolysis by Mg2+.

1983 • 57 citations

Conformational states of sarcoplasmic reticulum Ca2+-ATPase as studied by proteolytic cleavage

1985 • 53 citations

ATP driven ion pumps: an evolutionary mosaic

1989 • 46 citations

Conformational Change of Ca2+,Mg2+-Adenosine Triphosphatase of Sarcoplasmic Reticulum upon Binding of Ca2+ and Adenyl-5′-yl-Imidodiphosphate as Detected by Trypsin Sensitivity Analysis1

1984 • 27 citations