Malignant hyperthermia susceptibility: biochemical basis for pathogenesis and diagnosis.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Calcium release from the sarcoplasmic reticulum

1977 • 1,580 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

The adaptive response of skeletal muscle to increased use

1981 • 784 citations

Rapid calcium release from cardiac sarcoplasmic reticulum vesicles is dependent on Ca2+ and is modulated by Mg2+, adenine nucleotide, and calmodulin.

1987 • 489 citations

Kinetics of rapid calcium release by sarcoplasmic reticulum. Effects of calcium, magnesium, and adenine nucleotides

1986 • 456 citations

Mechanisms of Ca2+ release from sarcoplasmic reticulum of skeletal muscle

1984 • 330 citations

METABOLIC ERROR OF MUSCLE METABOLISM AFTER RECOVERY FROM MALIGNANT HYPERTHERMIA

1970 • 318 citations

Isolation of the ryanodine receptor from cardiac sarcoplasmic reticulum and identity with the feet structures.

1987 • 312 citations

Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia.

1988 • 238 citations

MALIGNANT HYPERTHERMIA: RELATIONSHIP TO OTHER DISEASES

1988 • 158 citations

Calcium‐induced Ca²⁺ release from sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia

1983 • 158 citations

Ca2+ release from sarcoplasmic reticulum of skinned fast- and slow-twitch muscle fibers

1988 • 144 citations

Abnormality in calcium release from skeletal sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia.

1983 • 142 citations

Biochemical Basis of Malignant Hyperpyrexia

1974 • 128 citations

Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles

1984 • 116 citations

Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs

1988 • 109 citations

Myopathy caused by a deficiency of Ca²⁺‐adenosine triphosphatase in sarcoplasmic reticulum (Brody's disease)

1986 • 103 citations

The caffeine test of isolated human muscle in relation to malignant hyperthermia

1977 • 98 citations

Porcine malignant hyperthermia carrier detection and chromosomal assignment using a linked probe

1988 • 94 citations

Prediction of the halothane (Hal) genotypes of pigs by deducing Hal, Phi, Po2, Pgd haplotypes of parents and offspring: results from a large‐scale practice in Swedish breeds

1985 • 93 citations

Enhanced Ca2+-induced calcium release by isolated sarcoplasmic reticulum vesicles from malignant hyperthermia susceptible pig muscle

1986 • 92 citations

Malignant hyperthermia

1985 • 82 citations

Halothane‐caffeine contracture testing in neuromuscular diseases

1988 • 69 citations

MALIGNANT HYPERTHERMIA: A HUMAN STRESS SYNDROME ?

1974 • 69 citations

Porcine Malignant Hyperthermia:

1975 • 60 citations

In vitro contracture tests for susceptibility to malignant hyperthermia.

1983 • 57 citations

Biochemical characterization of the Ca2+ release channel of skeletal and cardiac sarcoplasmic reticulum

1988 • 55 citations

Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.

1983 • 52 citations

Reconstitution of purified cardiac muscle calcium release channel (ryanodine receptor) in planar bilayers

1988 • 52 citations

Porcine malignant hyperthermia susceptibility: hypersensitive calcium-release mechanism of skeletal muscle sarcoplasmic reticulum.

1986 • 50 citations

Non-invasive Evaluation of Maliganant Hyperthermia Susceptibility with Phosphorus Nuclear Magnetic Resonance Spectroscopy

1988 • 49 citations

Epidemiology and Inheritance of Malignant Hyperthermia

1979 • 48 citations

Abnormal membrane properties of the sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia: Modes of action of halothane, caffeine, dantrolene, and two other drugs

1986 • 47 citations

Malignant hyperthermia and related neuromuscular diseases: Caffeine contracture of the skinned muscle fibers

1983 • 45 citations

The adenosine triphosphate (ATP) depletion test: Comparison with the caffeine contracture test as a method of diagnosing malignant hyperthermia susceptibility

1976 • 45 citations

Malignant hyperpyrexia myopathy.

1973 • 43 citations

Etiopathogenetic defect of malignant hyperthermia: Hypersensitive calcium-release channel of skeletal muscle sarcoplasmic reticulum

1987 • 41 citations

ANAESTHETIC-INDUCED INCREASE IN IONISED CALCIUM IN BLOOD MONONUCLEAR CELLS FROM MALIGNANT HYPERTHERMIA PATIENTS

1987 • 39 citations

Comparison of effects of several inhalation anaesthetics on caffeine-induced contractures of normal and malignant hyperthermic skeletal muscle

1980 • 38 citations

Canine malignant hyperthermia: diagnosis of susceptibility in a breeding colony.

1983 • 36 citations

Effect of temperature, time and fascicle size on the caffeine contracture test

1980 • 31 citations

Porcine malignant hyperthermia susceptibility: erythrocytic osmotic fragility.

1985 • 31 citations

Mechanical properties of normal and malignant hyperthemia susceptible porcine muscle: effects of halothane and other drugs.

1980 • 30 citations

Dantrolene -In vitro studies in malignant hyperthermia susceptible (MHS) and normal skeletal muscle

1984 • 26 citations

Changes in cytoplasmic free calcium caused by halothane. Role of the plasma membrane and intracellular Ca²⁺stores

1986 • 26 citations

Canine malignant hyperthermia susceptibility: erythrocytic defects--osmotic fragility, glucose-6-phosphate dehydrogenase deficiency and abnormal Ca2+ homeostasis.

1984 • 23 citations

Myoadenylate deaminase deficiency and malignant hyperthermia susceptibility: Is there a relationship?

1985 • 22 citations

Selective Increase in Cytoplasmic Calcium by Anesthetic in Lymphocytes from Malignant Hypothermia-Susceptible Pigs

1987 • 21 citations

Dantrolene does not block calcium pulse‐induced calcium release from a putative calcium channel in sarcoplasmic reticulum from malignant hyperthermia and normal pig muscle

1984 • 20 citations

Increased peroxidation of erythrocytes of stress-susceptible pigs: an improved diagnostic test for porcine stress syndrome.

1989 • 20 citations

Exercise-induced malignant hyperthermia in an English springer spaniel.

1987 • 19 citations

Influence of fluothane on calcium accumulation by the heavy microsomal fraction of human skeletal muscle: Comparison with a patient with malignant hyperpyrexia

1972 • 19 citations

Porcine malignant hyperthermia susceptibility: increased calcium-sequestering activity of skeletal muscle sarcoplasmic reticulum.

1986 • 19 citations

No Relationship Between Fiber Type and Halothane Contracture Test Results in Malignant Hyperthermia

1987 • 18 citations

Malignant hyperthermia: A disease of specific myofiber type?

1982 • 18 citations

The in-vitro caffeine contracture test: Influence of the muscle histochemical profile on test results

1982 • 14 citations

Blood antioxidant status and plasma pyruvate kinase activity of halothane-reacting pigs.

1987 • 13 citations

Sarcoplasmic reticulum Ca2+-ATPase and acylphosphatase activities in muscle biopsies from patients with Duchenne muscular dystrophy

1986 • 13 citations

Porcine malignant hyperthermia susceptibility: halothane-induced increase in cytoplasmic free calcium in lymphocytes.

1989 • 10 citations

Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia

1988 • 10 citations

Malignant hyperthermia susceptibility: cardiac histomorphometry of dogs and young and market-weight swine.

1987 • 10 citations

Erythrocyte Fragility Screening Is Not a Tool for Diagnosis of Human Malignant Hyperthermia

1987 • 9 citations

Verapamil and zero Ca2+ alter responses of cat muscle to halothane and caffeine

1986 • 9 citations

Studies of the halothane-cooling contractures of skeletal muscle

1987 • 7 citations

The temperature dependence of halothane‐induced contractures of skeletal muscle

1986 • 4 citations