A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 1,965 citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 • 1,902 citations

Nuclear Receptor Coregulators: Cellular and Molecular Biology*

1999 • 1,783 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

CBP/p300 in cell growth, transformation, and development

2000 • 1,712 citations

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

2000 • 1,658 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

CREB-binding Protein and p300 in Transcriptional Regulation

2001 • 847 citations

Nuclear Receptor Coregulators: Cellular and Molecular Biology

1999 • 779 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase

1999 • 630 citations

RNA Helicase A Mediates Association of CBP with RNA Polymerase II

1997 • 532 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 526 citations

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

1998 • 516 citations

The SRC family of nuclear receptor coactivators

2000 • 515 citations

Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element

1989 • 507 citations

Nuclear Receptor-Binding Sites of Coactivators Glucocorticoid Receptor Interacting Protein 1 (GRIP1) and Steroid Receptor Coactivator 1 (SRC-1): Multiple Motifs with Different Binding Specificities

1998 • 417 citations

Nuclear Hormone Receptor Coregulators In Action: Diversity For Shared Tasks

2000 • 377 citations

Peptide Antagonists of the Human Estrogen Receptor

1999 • 372 citations

A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity

1999 • 343 citations

p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation

1998 • 337 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A

1998 • 298 citations

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

1999 • 291 citations

The bromodomain: a chromatin-targeting module?

1999 • 270 citations

Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins

1999 • 262 citations

Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors.

1997 • 236 citations

Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract.

1987 • 228 citations

Biochemical Analysis of Distinct Activation Functions in p300 That Enhance Transcription Initiation with Chromatin Templates

1999 • 227 citations

Linking histone acetylation to transcriptional regulation

1998 • 222 citations

Chromatin-modifying and -remodeling complexes

1999 • 217 citations

p300-Mediated acetylation facilitates the transfer of histone H2A–H2B dimers from nucleosomes to a histone chaperone

2000 • 209 citations

Activator-Dependent Transcription from Chromatin In Vitro Involving Targeted Histone Acetylation by p300

2000 • 200 citations

Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro.

1989 • 187 citations

Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast.

1993 • 186 citations

ATP-Driven Chromatin Remodeling Activity and Histone Acetyltransferases Act Sequentially during Transactivation by RAR/RXR In Vitro

2000 • 184 citations

ATP-Dependent Nucleosome Reconfiguration and Transcriptional Activation from Preassembled Chromatin Templates

1994 • 163 citations

The estrogen receptor family

1999 • 128 citations

p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin

2000 • 126 citations

E1A directly binds and regulates the P/CAF acetyltransferase

1998 • 124 citations

Nuclear Hormone Receptor Coregulators In Action: Diversity For Shared Tasks

2000 • 114 citations

The Nucleosome: A Powerful Regulator of Transcription

1998 • 109 citations

Analysis of the Steroid Receptor Coactivator 1 (SRC1)-CREB Binding Protein Interaction Interface and Its Importance for the Function of SRC1

2001 • 109 citations

p300 Forms a Stable, Template-Committed Complex with Chromatin: Role for the Bromodomain

2001 • 94 citations

The Receptor-associated Coactivator 3 Activates Transcription through CREB-binding Protein Recruitment and Autoregulation

1998 • 88 citations

Characterization of an E1A-CBP Interaction Defines a Novel Transcriptional Adapter Motif (TRAM) in CBP/p300

1999 • 79 citations

p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption

1999 • 78 citations

Specificity of Cyclin E-Cdk2, TFIIB, and E1A Interactions with a Common Domain of the p300 Coactivator

1999 • 56 citations

Activation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro

1989 • 56 citations

Chromatin assembly on plasmid DNA in vitro

1991 • 41 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 37 citations

Adenovirus E1A Specifically Blocks SWI/SNF-Dependent Transcriptional Activation

1996 • 32 citations

Transcriptional Analysis of Chromatin Assembled with Purified ACF and dNAP1 Reveals That Acetyl-CoA Is Required for Preinitiation Complex Assembly

2000 • 27 citations

Use of Suppressor Mutants To Probe the Function of Estrogen Receptor-p160 Coactivator Interactions

2001 • 15 citations

Ligand- and cofactor-regulated transcription with chromatin templates

1999 • 9 citations