Back to search

Repeated Exposure to Rewarding Brain Stimulation Downregulates GluR1 Expression in the Ventral Tegmental Area

Data up to Jan 2025

Published2001
Citations41
References45

Total Citations Per Year

Abstract

References (45)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum.

1990 • 958 citations

The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

1998 • 936 citations

Addictive Drugs and Brain Stimulation Reward

1996 • 777 citations

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

1999 • 630 citations

Calcium- and activity-dependent synaptic plasticity

1999 • 618 citations

Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration

1990 • 574 citations

Molecular Mechanisms of Drug Reinforcement and Addiction

1995 • 573 citations

Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine

1989 • 480 citations

Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents

1996 • 454 citations

Sensitization to Morphine Induced by Viral-Mediated Gene Transfer

1997 • 279 citations

Preexposure sensitizes rats to the rewarding effects of cocaine

1990 • 273 citations

RNA editing of brain glutamate receptor channels: mechanism and physiology1Published on the World Wide Web on 5 February 1998.1

1998 • 263 citations

Repeated Cocaine Alters Glutamate Receptor Subunit Levels in the Nucleus Accumbens and Ventral Tegmental Area of Rats that Develop Behavioral Sensitization

1999 • 241 citations

Amphetamine-Induced Behavior, Dopamine Release, and c-fosmRNA Expression: Modulation by Environmental Novelty

1998 • 228 citations

Morphine and Cocaine Exert Common Chronic Actions on Tyrosine Hydroxylase in Dopaminergic Brain Reward Regions

1991 • 211 citations

Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors.

1997 • 210 citations

Cloned Glutamate Receptors

1994 • 176 citations

Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus

1997 • 125 citations

Quantitative determination of the effects of catecholaminergic agonists and antagonists on the rewarding efficacy of brain stimulation

1987 • 113 citations

Psychomotor stimulant- and opiate-induced c-fos mRNA expression patterns in the rat forebrain: Comparisons between acute drug treatment and a drug challenge in sensitized animals

1996 • 110 citations

Distinct Sites of Opiate Reward and Aversion within the Midbrain Identified Using a Herpes Simplex Virus Vector Expressing GluR1

2000 • 100 citations

Self-stimulation in the rat: Quantitative characteristics of the reward pathway.

1978 • 90 citations

Down‐Regulation of AMPA Receptor Subunit GluR2 in Amygdaloid Kindling

1995 • 88 citations

Potentiation of lateral hypothalamic and midline mesencephalic brain stimulation reinforcement by nicotine: examination of repeated treatment.

1994 • 74 citations

Rewarding brain stimulation induces only sparse Fos-like immunoreactivity in dopaminergic neurons

1998 • 68 citations

Synergistic effects of cocaine with lateral hypothalamic brain stimulation reward: lack of tolerance or sensitization.

1997 • 55 citations

The effect of chronic cocaine on self-stimulation train-duration thresholds

1988 • 53 citations

Opioid-neuroleptic interaction in brainstem self-stimulation

1989 • 52 citations

Effects of repeated amphetamine injections on lateral hypothalamic brain stimulation reward and subsequent locomotion

1993 • 47 citations

Fos-like immunoreactivity in forebrain regions following self-stimulation of the lateral hypothalamus and the ventral tegmental area

1997 • 43 citations

Fos-like immunoreactivity in the caudal diencephalon and brainstem following lateral hypothalamic self-stimulation

1997 • 41 citations

Addictive Drugs and Brain Stimulation Reward

1996 • 38 citations

Calcium and Activity-Dependent Synaptic Plasticity

1998 • 36 citations

Regional differences in desensitization of c-Fos expression following repeated self-stimulation of the medial forebrain bundle in the rat

1999 • 34 citations

Phencyclidine-induced potentiation of brain stimulation reward: acute effects are not altered by repeated administration

1993 • 34 citations

Molecular Mechanisms of Drug Reinforcement and Addiction

1995 • 32 citations

Lack of sensitization or tolerance to the facilitating effect of ventral tegmental area morphine on lateral hypothalamic brain stimulation reward

1993 • 30 citations

Repeated stimulation of the ventral tegmental area sensitizes the hyperlocomotor response to amphetamine

1994 • 28 citations

Neonatal dopamine depletions spare lateral hypothalamic stimulation reward in adult rats

1988 • 18 citations

Activation of reward-relevant neurons in the caudate-putamen influences the development of medial prefrontal cortex self-stimulation: a moveable electrode mapping study

1998 • 8 citations

Cited By (0)

Loading...