Sensitization to Morphine Induced by Viral-Mediated Gene Transfer

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Ca2 ⁺ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

1991 • 1,458 citations

Factors That Predict Individual Vulnerability to Amphetamine Self-Administration

1989 • 1,354 citations

Steric Effects in Electrolytes: A Modified Poisson-Boltzmann Equation

1997 • 884 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

Molecular Mechanisms of Drug Reinforcement and Addiction

1995 • 573 citations

Intracranial self-administration of morphine into the ventral tegmental area in rats

1981 • 497 citations

Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine

1989 • 480 citations

Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents

1996 • 454 citations

Long-Term Behavioral Recovery in Parkinsonian Rats by an HSV Vector Expressing Tyrosine Hydroxylase

1994 • 333 citations

Regulation of ERK ( Extracellular Signal Regulated Kinase), Part of the Neurotrophin Signal Transduction Cascade, in the Rat Mesolimbic Dopamine System by Chronic Exposure to Morphine or Cocaine

1996 • 295 citations

Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons.

1996 • 276 citations

The effect of dopamine receptor blockade on the development of sensitization to the locomotor activating effects of amphetamine and morphine

1989 • 242 citations

Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system

1995 • 222 citations

The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons

1995 • 222 citations

Agonist-activated cobalt uptake identifies divalent cation—Permeable kainate receptors on neurons and glial cells

1991 • 214 citations

Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors.

1997 • 210 citations

Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens

1992 • 181 citations

Gene Transfer to Neurons Using Herpes Simplex Virus-Based Vectors

1996 • 171 citations

DNQX blockade of amphetamine behavioral sensitization

1991 • 163 citations

Generation of High-Titer Defective HSV-1 Vectors Using an IE 2 Deletion Mutant and Quantitative Study of Expression in Cultured Cortical Cells

1996 • 136 citations

5′ Upstream DNA sequence of the rat tyrosine hydroxylase gene directs high-level and tissue-specific expression to catecholaminergic neurons in the central nervous system of transgenic mice

1994 • 124 citations

Individual differences in the psychomotor effects of morphine are predicted by reactivity to novelty and influenced by corticosterone secretion

1993 • 110 citations

Behavioral effects of lesions in the A10 dopaminergic area of the rat

1977 • 107 citations

Influence of Cocaine on the JAK–STAT Pathway in the Mesolimbic Dopamine System

1996 • 59 citations

Individual Differences in Locomotor Activity Are Associated with Levels of Tyrosine Hydroxylase and Neurofilament Proteins in the Ventral Tegmental Area of Sprague-Dawley Rats

1993 • 22 citations

The genetic basis of ataxia.

1995 • 12 citations