TAK1 Mitogen-activated Protein Kinase Kinase Kinase Is Activated by Autophosphorylation within Its Activation Loop

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Biologic basis for interleukin-1 in disease

1996 • 4,324 citations

Mitogen-activated protein kinase pathways

1997 • 2,513 citations

How MAP Kinases Are Regulated

1995 • 1,742 citations

Active and Inactive Protein Kinases: Structural Basis for Regulation

1996 • 1,361 citations

Regulation of transcription by MAP kinase cascades

1996 • 1,330 citations

Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction

1995 • 1,318 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

1999 • 1,163 citations

MAP kinase pathways in yeast: For mating and more

1995 • 1,009 citations

MAPKs: new JNK expands the group

1994 • 949 citations

IRAK: A Kinase Associated with the Interleukin-1 Receptor

1996 • 894 citations

Mitogen-activated protein kinase cascades and regulation of gene expression

1996 • 759 citations

TAB1: An Activator of the TAK1 MAPKKK in TGF-β Signal Transduction

1996 • 582 citations

A Novel Kinase Cascade Mediated by Mitogen-activated Protein Kinase Kinase 6 and MKK3

1996 • 443 citations

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1998 • 435 citations

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

1999 • 388 citations

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1998 • 351 citations

TAK1 Mediates the Ceramide Signaling to Stress-activated Protein Kinase/c-Jun N-terminal Kinase

1997 • 336 citations

MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?

1997 • 318 citations

Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator

1998 • 289 citations

Tumor Necrosis Factor Signaling to Stress-activated Protein Kinase (SAPK)/Jun NH2-terminal Kinase (JNK) and p38

1998 • 267 citations

IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae.

1989 • 251 citations

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

1998 • 234 citations

Isolation of MEK5 and Differential Expression of Alternatively Spliced Forms

1995 • 221 citations

Activation of the Hematopoietic Progenitor Kinase-1 (HPK1)-dependent, Stress-activated c-Jun N-terminal Kinase (JNK) Pathway by Transforming Growth Factor β (TGF-β)-activated Kinase (TAK1), a Kinase Mediator of TGF β Signal Transduction

1997 • 193 citations

A Novel Human STE20-related Protein Kinase, HGK, That Specifically Activates the c-Jun N-terminal Kinase Signaling Pathway

1999 • 173 citations

[12] Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

1991 • 170 citations

Dimerization via Tandem Leucine Zippers Is Essential for the Activation of the Mitogen-activated Protein Kinase Kinase Kinase, MLK-3

1998 • 128 citations

Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain

1997 • 71 citations

Identification of Two Essential Phosphorylated Threonine Residues In the Catalytic Domain of Mekk1

1997 • 67 citations

Receptor signaling: Dimerization and beyond

1996 • 29 citations