Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

1996 • 2,306 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus Embryos

1991 • 2,082 citations

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

1996 • 1,962 citations

Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction

1995 • 1,318 citations

Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

1996 • 899 citations

MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma

1996 • 855 citations

Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis

1997 • 797 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

1994 • 737 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Programmed cell death during Drosophila embryogenesis

1993 • 710 citations

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

1996 • 710 citations

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.

1995 • 682 citations

A human Mad protein acting as a BMP-regulated transcriptional activator

1996 • 674 citations

Xenopus embryos regulate the nuclear localization of XMyoD.

1994 • 648 citations

Human Type II Receptor for Bone Morphogenic Proteins (BMPs): Extension of the Two-Kinase Receptor Model to the BMPs

1995 • 602 citations

TAB1: An Activator of the TAK1 MAPKKK in TGF-β Signal Transduction

1996 • 582 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

Requirement for BMP Signaling in Interdigital Apoptosis and Scale Formation

1996 • 552 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

A Novel Kinase Cascade Mediated by Mitogen-activated Protein Kinase Kinase 6 and MKK3

1996 • 443 citations

Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily

1996 • 432 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

The Immunophilin FKBP12 Functions as a Common Inhibitor of the TGFβ Family Type I Receptors

1996 • 370 citations

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

1993 • 354 citations

Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1

1997 • 354 citations

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway.

1996 • 351 citations

Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP‐2 and BMP‐4

1995 • 344 citations

Mechanism of TGFβ receptor inhibition by FKBP12

1997 • 342 citations

Specific Interaction of Type I Receptors of the TGF-β Family with the Immunophilin FKBP-12

1994 • 321 citations

Mad-related genes in the human

1996 • 308 citations

Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication

1994 • 267 citations

The Nature of the 660-Kilometer Upper-Mantle Seismic Discontinuity from Precursors to the PP Phase

1996 • 245 citations

Identification of a Human Type II Receptor for Bone Morphogenetic Protein-4 That Forms Differential Heteromeric Complexes with Bone Morphogenetic Protein Type I Receptors

1995 • 238 citations

BMP-2/-4 mediate programmed cell death in chicken limb buds

1996 • 228 citations

Cloning of a Novel Type II Serine/Threonine Kinase Receptor through Interaction with the Type I Transforming Growth Factor-β Receptor

1995 • 189 citations

Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor

1996 • 172 citations

Smad5 Induces Ventral Fates inXenopusEmbryo

1997 • 157 citations

A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis

1997 • 134 citations

The p21 ^RAS Farnesyltransferase α Subunit in TGF-β and Activin Signaling

1996 • 128 citations

Dorsalization of mesoderm induction by lithium

1989 • 109 citations

Interaction of the Transforming Growth Factor-β Type I Receptor with Farnesyl-protein Transferase-α

1995 • 106 citations

Bone morphogenetic protein 2 in the early development of Xenopus laevis

1995 • 103 citations