Constitutive and aroclor 1254-induced hepatic glutathione S-transferase, peroxidase and reductase activities in genetically inbred mice

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Glutathione S-Transferases

1974 • 17,321 citations

Glutathione peroxidase activity in selenium-deficient rat liver

1976 • 3,413 citations

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

Glutathione: Metabolism and function

1978 • 971 citations

The Isoenzymes of Glutathione Transferase

1985 • 960 citations

The P450 Gene Superfamily: Recommended Nomenclature

1987 • 812 citations

Chemicals, Drugs, and Lipid Peroxidation

1976 • 520 citations

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

1979 • 401 citations

The role of glutathione in detoxication

1983 • 377 citations

Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants.

1978 • 338 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase Activity

1974 • 326 citations

Glutathione <italic>S</italic>-Transferase Activity: Enhancement by Compounds Inhibiting Chemical Carcinogenesis and by Dietary Constituents<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1982 • 325 citations

TheAhLocus: Genetic Regulation of the Metabolism of Carcinogens, Drugs, and Other Environmental Chemicals by Cytochrome P-450-Mediated Monooxygenase

1979 • 317 citations

Reactions of Alpha Methylene Lactone Tumor Inhibitors with Model Biological Nucleophiles

1970 • 296 citations

Genetic Mechanisms Controlling the Induction of Polysubstrate Monooxygenase (P-450) Activities

1981 • 296 citations

Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.

1974 • 293 citations

The Regulation of Cytochrome P-450 Gene Expression

1986 • 283 citations

Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes

1982 • 265 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase by 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Evidence for a Receptor Mutation in Genetically Non-responsive Mice

1975 • 238 citations

Elevation of extrahepatic glutathione S-transferase and epoxide hydratase activities by 2(3)-tert-butyl-4-hydroxyanisole.

1979 • 200 citations

Differences in stereoselectivity and catalytic efficiency of three human glutathione transferases in the conjugation of glutathione with 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.

1986 • 170 citations

The influence of phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin on glutathione s-transferase activity of rat liver cytosol

1978 • 148 citations

Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse.

1982 • 139 citations

Biochemical Basis of Chemical Carcinogenesis

1985 • 132 citations

Mouse‐Liver Glutathione Reductase

1979 • 117 citations

Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization

1977 • 89 citations

Rat glutathione S-transferases supergene family. Characterization of an anionic Yb subunit cDNA clone.

1986 • 80 citations

On the multiplicity of rat liver glutathione S-transferases.

1985 • 60 citations

Tumor inhibitors. LVII. Reaction of endocyclic .alpha.,.beta.-unsaturated .gamma.-lactones with thiols

1970 • 60 citations

Paracetamol metabolism in the isolated perfused rat liver with further metabolism of a biliary paracetamol conjugate by the small intestine

1979 • 60 citations

PCBs and PBBs: Biologic and toxic effects on C57BL/6J and DBA/2J inbred mice

1984 • 54 citations

Rat hepatic cytochrome P-450 isozyme specificity for the metabolism of the steroid sulfate, 5α-androstane-3α,17β-diol-3,17-disulfate

1984 • 52 citations

Difference in the effects of phenobarbital and 3-methylcholanthrene treatment on subunit composition of hepatic glutathioneS-transferase in male and female rats

1987 • 52 citations

Identification of heterogeneous and microheterogeneous subunits of glutathione S-transferase in rat liver cytosol

1985 • 46 citations

Species difference in glutathione level and glutathione related enzyme activities in rats, mice, guinea pigs and hamsters.

1983 • 44 citations

Pesticides as inducers of hepatic drug-metabolizing enzymes—II. Glutathione S-transferases

1980 • 41 citations

Induction of cytosolic glutathione transferase and microsomal epoxide hydrolase activities in extrahepatic organs of the rat by phenobarbital, 3-methylcholanthrene andtrans-stilbene oxide

1984 • 36 citations

Differences in the occurrence of glutathione transferase isoenzymes in rat lung and liver

1985 • 30 citations

Induction of translationally active rat liver glutathione S-transferase B messenger RNA by phenobarbital

1981 • 29 citations

Biochemical effects of pure isomers of hexachlorobiphenyl—Hepatic microsomal epoxide hydrase and cytosolic glutathione S-transferase activities in the rat

1979 • 27 citations

Sensitive measurement of glutathione using isocratic high-performance liquid chromatography with fluorescence detection

1986 • 23 citations

Binding of benzo(a)pyrene to rat lung glutathione S‐transferases in vivo

1985 • 16 citations

A Comparison of Induction of Microsomal Glutathione S-Transferase Activity in the Liver of the Mouse and Rat by Dietary 2(3)-tert-Butyl-4-hydroxyanisole (BHA).

1982 • 14 citations

Hepatic Glutathione S-Transferase Activity in Mice: Effects of Avy/- Genotype, Obesity, Lindane Treatment, and Sex

1986 • 7 citations