Comparison of polychlorinated dibenzodioxin levels with hepatic mixed‐function oxidase induction in great blue herons

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1953 • 4,357 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene.

1974 • 1,562 citations

Polychlorinated Biphenyls (PCBs) and Polybrominated Biphenyls (PBBs): Biochemistry, Toxicology, and Mechanism of Action

1984 • 793 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat

1985 • 653 citations

Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan-1983

1989 • 410 citations

STUDIES ON THE MECHANISM OF ACTION OF THE CHLORINATED DIBENZO‐p‐DIOXINS AND RELATED COMPOUNDS*

1979 • 336 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase Activity

1974 • 326 citations

The Toxicity of Polychlorinated Polycyclic Compounds and Related Chemicals

1973 • 310 citations

Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships.

1983 • 307 citations

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

1985 • 301 citations

Separation of pure polychlorinated biphenyl isomers into two types of inducers on the basis of induction of cytochrome P-450 or P-448

1977 • 252 citations

Genetic Control of Drug Levels in Man: Antipyrine

1968 • 225 citations

Chlorinated dibenzo-p-dioxins: potent inducers of delta-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase. II. A study of the structure-activity relationship.

1973 • 218 citations

Inherent specificities of purified cytochromes P-450 and P-448 toward biphenyl hydroxylation and ethoxyresorufin deethylation.

1975 • 209 citations

PCB isomers and congeners: Induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells

1982 • 184 citations

Genetic Control of Drug Levels in Man: Phenylbutazone

1968 • 178 citations

Polychlorinated dibenzofurans (PCDFs): Effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity

1984 • 150 citations

Toxicity and 7-ethoxyresorufin O-deethylase-inducing potency of coplanar polychlorinated biphenyls (PCBs) in chick embryos

1988 • 145 citations

Polychlorinated dibenzo-p-dioxins: Quantitative in vitro and in vivo structure-activity relationships

1986 • 139 citations

Embryotoxicity, teratogenicity, and aryl hydrocarbon hydroxylase activity in forster's terns on green bay, lake michigan

1987 • 135 citations

TOXICOPATHOLOGY CHARACTERISTICS OF THE HALOGENATED AROMATICS

1979 • 122 citations

Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme induction and immunotoxicity

1987 • 120 citations

Etiology of chick edema disease.

1973 • 113 citations

Induction of Enzyme Activity in Cell Culture: A Rapid Screen for Detection of Planar Poly chlorinated Organic Compounds

1979 • 112 citations

Environmental contaminants and reproductive success of great blue herons Ardea herodias in British Columbia, 1986–1987

1989 • 111 citations

Inductive effect on hepatic enzymes and acute toxicity of individual polychlorinated dibenzofuran congeners in rats

1981 • 101 citations

Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo.

1983 • 97 citations

Presence of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in fish-eating birds and fish from The Netherlands

1987 • 95 citations

Environmental contamination by polychlorinated dibenzo-p-dioxins and dibenzofurans associated with pulp and paper mill discharge

1987 • 92 citations

Comparative induction of aryl hydrocarbon hydroxylase activity in vitro by analogues of dibenzo-p-dioxin

1980 • 88 citations

Toxicological assessment of hexachlorobiphenyl isomers and 2,3,7,8-tetrachlorodibenzofuran in chicks

1976 • 84 citations

A Gel-Permeation/Column Chromatography Cleanup Method for the Determination of CDDs in Animal Tissue

1986 • 77 citations

Toxicology of PCBs for Mammals and for Birds

1972 • 75 citations

Cardiovascular teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the chick embryo

1981 • 75 citations

Differences in sensitivity of some avian species to the embryotoxicity of a PCB, 3,3′,4,4′-tetrachlorobiphenyl, injected into the eggs

1986 • 73 citations

Characterization of mixed‐function oxidase systems of the nestling herring gull and its implications for bioeffects monitoring

1986 • 64 citations

Studies on the pregnenolone-16α-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase

1987 • 63 citations

Determination, fate, and potential significance of PCBs in fish and sediment samples with emphasis on selected AHH-inducing congeners

1988 • 63 citations

Tissue porphyrin pattern determination by high-speed high-performance liquid chromatography

1986 • 51 citations

Comparisons of warfarin metabolism by liver microsomes of rats treated with a series of polybrominated biphenyl congeners and by the component-purified cytochrome P-450 isozymes

1983 • 46 citations

Ontogeny of the chicken cytochrome P-450 enzyme system

1987 • 42 citations

A comparative study of polychlorinated dibenzofurans, polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin on aryl hydrocarbon hydroxylase inducing potency in rats

1983 • 41 citations

Immunotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in a complex environmental mixture from the Love Canal

1989 • 33 citations

Coordinate induction of cytochrome P-448 mediated mixed function oxidases and histopathologic changes produced acutely in chick embryo liver by polychlorinated biphenyl congeners

1984 • 33 citations

Induction of P-450 isoenzyme activities in Syrian golden hamster liver compared to rat liver as probed by the rate of 7-alkoxyresorufin-O-dealkylation

1988 • 26 citations

Toxicology of PCBs for Mammals and for Birds

1972 • 15 citations

PRELIMINARY APPRAISAL OF TETRA- TO OCTACHLORODIBENZODIOXIN CONTAMINATION IN EGGS OF VARIOUS SPECIES OF WILDLIFE IN CANADA

1983 • 13 citations

Etiology of Chick Edema Disease

1973 • 11 citations

Induction of acute renal porphyria in Japanese quail by Aroclor 1254

1986 • 8 citations