The human T-cell rearranging gamma (TRG) genes and the gamma T-cell receptors

Identification of a putative second T-cell receptor

1986 • 980 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Developmental regulation of T-cell receptor gene expression

1985 • 522 citations

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

1987 • 483 citations

A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes

1987 • 446 citations

A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

1986 • 430 citations

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

1986 • 423 citations

Diversity, rearrangement, and expression of murine T cell gamma genes

1986 • 405 citations

Structure, organization, and somatic rearrangement of T cell gamma genes

1985 • 395 citations

Two forms of the T-cell receptor γ protein found on peripheral blood cytotoxic T lymphocytes

1987 • 391 citations

Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types

1985 • 382 citations

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

1986 • 332 citations

A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production

1986 • 331 citations

Diversity and rearrangement of the human T cell rearranging γ genes: Nine germ-line variable genes belonging to two subgroups

1986 • 329 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

1986 • 308 citations

Complexity of human T-cell antigen receptor β-chain constant- and variable-region genes

1984 • 213 citations

Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7

1985 • 205 citations

A γ-chain complex forms a functional receptor on cloned human lymphocytes with natural killer-like activity

1987 • 199 citations

Mechanisms of divergence and convergence of the human immunoglobulin α1 and α2 constant region gene sequences

1984 • 195 citations

Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus

1986 • 180 citations

Rearrangement of two distinct T-cell γ-chain variable-region genes in human DNA

1986 • 174 citations

New subgroups in the human T cell rearranging V gamma gene locus.

1987 • 170 citations

The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer.

1987 • 164 citations

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

1986 • 154 citations

A novel subset of human lymphocytes with a T cell receptor-gamma complex.

1987 • 145 citations

A unique V-J-C-rearranged gene encodes a gamma protein expressed on the majority of CD3+ T cell receptor-alpha/beta- circulating lymphocytes.

1988 • 133 citations

Human T-Cell γ Chain Genes: Organization, Diversity, and Rearrangement

1986 • 129 citations

A unique T-cell receptor complex expressed on human fetal lymphocytes displaying natural-killer-like activity

1986 • 120 citations

Rearrangements to the JP1, JP and JP2 segments in the human T‐cell rearranging gamma gene (TRGγ) locus

1987 • 119 citations

Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes.

1988 • 117 citations

Human T cell gamma chain joining regions and T cell development.

1987 • 114 citations

The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia.

1985 • 107 citations

Human T cell gamma genes are frequently rearranged in B-lineage acute lymphoblastic leukemias but not in chronic B cell proliferations.

1987 • 106 citations

Characterization of an expressed CDS-associated Ti γ-chain reveals Cγ domain polymorphism

1987 • 101 citations

Repertoire of the human T cell gamma genes: high frequency of nonfunctional transcripts in thymus and mature T cells

1987 • 92 citations

Rearrangements of immunoglobulin and T cell receptor beta and gamma genes are associated with terminal deoxynucleotidyl transferase expression in acute myeloid leukemia.

1987 • 88 citations

Human T-cell γ genes contain N segments and have marked junctional variability

1986 • 87 citations

Structurally Divergent Human T Cell Receptor γ Proteins Encoded by Distinct Cγ Genes

1987 • 84 citations

Human T cell gamma-chain gene rearrangements in acute lymphoid and nonlymphoid leukemia: comparison with the T cell receptor beta-chain gene.

1986 • 81 citations

Heterogeneity of T-cell beta-chain gene rearrangements in human leukaemias and lymphomas.

1985 • 81 citations

Structure and Diversity of the Human T-Cell Receptor β-Chain Variable Region Genes

1986 • 74 citations

Lysis of tumor cells by CD3+4-8-16+ T cell receptor alpha beta- clones, regulated via CD3 and CD16 activation sites, recombinant interleukin 2, and interferon beta 1.

1987 • 69 citations

Normal T cell development is possible without ‘functional’ gamma chain genes.

1986 • 60 citations

A new mouse TCR V gamma gene that shows remarkable evolutionary conservation.

1987 • 57 citations

Molecular Diversity of the Human T-Gamma Constant Region Genes

1987 • 57 citations

Measuring the Human T Cell Receptor γ-Chain Locus

1987 • 52 citations

Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias

1987 • 40 citations

Unusual forms of T cell γ mRNA in a human T cell leukemia cell line: Implications for γ gene expression

1987 • 36 citations

T cell rearranging gene gamma: diversity and mRNA expression in fresh cells from T cell acute lymphoblastic leukemia

1987 • 35 citations

Nonrandom TRG_γ variable gene rearrangement in normal human T cells and T cell leukemias

1988 • 23 citations