Enhanced Expression of Eotaxin and CCR3 in Atopic Dermatitis

Diagnostic Features of Atopic Dermatitis

1980 • 4,910 citations

Atopic Dermatitis

2000 • 4,717 citations

Chemokines — Chemotactic Cytokines That Mediate Inflammation

1998 • 3,660 citations

Human Chemokines: An Update

1997 • 2,235 citations

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

1998 • 2,048 citations

Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells

1997 • 1,073 citations

Clinical Validation and Guidelines for the SCORAD Index: Consensus Report of the European Task Force on Atopic Dermatitis

1997 • 1,005 citations

Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis.

1994 • 780 citations

A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis

1998 • 721 citations

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.

1996 • 719 citations

Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia

1996 • 698 citations

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.

1996 • 626 citations

Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

1996 • 561 citations

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.

1997 • 489 citations

Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co‐localization of eotaxin mRNA to bronchial epithelial and endothelial cells

1997 • 429 citations

Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation.

1997 • 419 citations

Molecular Cloning of Human Eotaxin, an Eosinophil-selective CC Chemokine, and Identification of a Specific Eosinophil Eotaxin Receptor, CC Chemokine Receptor 3

1996 • 412 citations

The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

1998 • 409 citations

Lesional expression of interferon-γ in atopic eczema

1994 • 404 citations

High Frequency of IL-4–Producing CD4+ Allergen-Specific T Lymphocytes in Atopic Dermatitis Lesional Skin

1991 • 397 citations

TH1 and TH2 in Human Diseases

1996 • 390 citations

Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis

1992 • 388 citations

Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids.

1997 • 369 citations

Cutting Edge: The Chemokine Receptor CCR8 Is Preferentially Expressed in Th2 But Not Th1 Cells

1998 • 341 citations

IL-4 Induces Eotaxin: A Possible Mechanism of Selective Eosinophil Recruitment in Helminth Infection and Atopy

1998 • 301 citations

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

1997 • 292 citations

Immunohistochemical Study of the β-Chemokine Receptors CCR3 and CCR5 and Their Ligands in Normal and Alzheimer's Disease Brains

1998 • 277 citations

Overexpression of IL-10 in atopic dermatitis. Contrasting cytokine patterns with delayed-type hypersensitivity reactions.

1995 • 274 citations

Eotaxin mRNA and Protein Expression in Chronic Sinusitis and Allergen-induced Nasal Responses in Seasonal Allergic Rhinitis

1997 • 208 citations

Detection of cytokine producing cells in the synovial membrane from patients with rheumatoid arthritis.

1995 • 176 citations

Serum eosinophil cationic protein (ECP) is a sensitive measure for disease activity in atopic dermatitis

1992 • 168 citations

Dendritic Cells Express Multiple Chemokine Receptors Used as Coreceptors for HIV Entry

1998 • 167 citations

The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: relationship to eosinophil, T cell, and macrophage recruitment.

1995 • 145 citations

Eotaxin Expression and Eosinophilic Inflammation in Asthma

1997 • 136 citations

Eotaxin Is a Potent Chemotaxin for Human Basophils

1997 • 105 citations

Human Dermal Fibroblasts Express Eotaxin: Molecular Cloning, mRNA Expression, and Identification of Eotaxin Sequence Variants

1996 • 105 citations

Chemokines as Mediators of Allergic Inflammation

1996 • 87 citations

Predominance of T lymphocytes in the dermal infiltrate of atopic dermatitis

1979 • 65 citations

Role of eosinophil-chemotactic C-C chemokines in cutaneous inflammation

1996 • 62 citations

CC chemokine receptors 1 and 3 are differentially regulated by IL-5 during maturation of eosinophilic HL-60 cells.

1998 • 53 citations

CC Chemokine Receptors 1 and 3 Are Differentially Regulated by IL-5 During Maturation of Eosinophilic HL-60 Cells

1998 • 48 citations

The immunology of atopic dermatitis

1991 • 23 citations

Molecular mechanisms involved in the regulation of gene expression during cell differentiation and development.

1990 • 13 citations