The proton-ATPase of bacteria and mitochondria

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

Complete sequence of bovine mitochondrial DNA conserved features of the mammalian mitochondrial genome

1982 • 1,491 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Linkage map of Escherichia coli K-12, edition 6

1980 • 785 citations

Molecular mechanisms for proton transport in membranes.

1978 • 566 citations

Vectorial Chemistry and the Molecular Mechanics of Chemiosmotic Coupling: Power Transmission by Proticity

1976 • 431 citations

Mechanism of ATP hydrolysis by beef heart mitochondrial ATPase. Rate constants for elementary steps in catalysis at a single site.

1982 • 409 citations

Linkage map of Escherichia coli K-12, edition 6.

1980 • 362 citations

Stoichiometry of subunits in the H+-ATPase complex of Escherichia coli.

1982 • 356 citations

Membrane proteins in energy transduction

1979 • 356 citations

Mechanism of ATP hydrolysis by beef heart mitochondrial ATPase. Rate enhancements resulting from cooperative interactions between multiple catalytic sites.

1982 • 348 citations

Catalytic site cooperativity of beef heart mitochondrial F1 adenosine triphosphatase. Correlations of initial velocity, bound intermediate, and oxygen exchange measurements with an alternating three-site model.

1982 • 347 citations

THE PURPLE MEMBRANE FROM HALOBACTERIUM HALOBIUM

1977 • 336 citations

The Mechanism and Regulation of ATP Synthesis by F1-ATPases

1981 • 310 citations

The presence of two hydrolytic sites on beef heart mitochondrial adenosine triphosphatase.

1981 • 305 citations

Cytochrome c oxidase

1980 • 305 citations

The structure of mitochondrial ATPase

1973 • 284 citations

Adenine nucleotide binding sites on beef heart F1-ATPase. Evidence for three exchangeable sites that are distinct from three noncatalytic sites.

1982 • 282 citations

Reconstitution of a functional coupling factor from the isolated subunits of Escherichia coli F1 ATPase.

1980 • 276 citations

Oxidative phosphorylation in Escherichia coli K 12. Mutations affecting magnesium ion- or calcium ion-stimulated adenosine triphosphatase

1971 • 274 citations

ATPase of Escherichia coli: purification, dissociation, and reconstitution of the active complex from the isolated subunits

1976 • 270 citations

Structures of the genes for the β and ε subunits of spinach chloroplast ATPase indicate a dicistronic mRNA and an overlapping translation stop/start signal

1982 • 270 citations

The Proton-Translocating Pumps of Oxidative Phosphorylation

1980 • 256 citations

Assembly of the mitochondrial membrane system: Sequence analysis of a yeast mitochondrial ATPase gene containing the oli-2 and oli-4 loci

1980 • 237 citations

The atp operon: nucleotide sequence of the promoter and the genes for the membrane proteins, and the δ subunit of Escherichia coli ATP-synthase

1981 • 229 citations

On the Structure and Genetics of the Proteolipid Subunit of the ATP Synthase Complex

1981 • 227 citations

Membrane Adenosine Triphosphatases of Prokaryotic Cells

1979 • 216 citations

Identification of a tyrosine residue at a nucleotide binding site in the beta subunit of the mitochondrial ATPase with p-fluorosulfonyl[14C]-benzoyl-5'-adenosine.

1978 • 207 citations

The atp operon: nucleotide sequence of the genes for the γ, β, and ε subunits of Escherichia coli ATP synthase

1981 • 207 citations

A highly stable adenosine triphosphatase from a thermophillie bacterium. Purification, properties, and reconstitution.

1975 • 206 citations

Reconstitution of adenosine triphosphatase of thermophilic bacterium from purified individual subunits.

1977 • 194 citations

Energy-transducing H+-ATPase of Escherichia coli. Purification, reconstitution, and subunit composition.

1979 • 180 citations

Purification and properties of a dicyclohexylcarbodiimide-sensitive adenosine triphosphatase from a thermophilic bacterium.

1975 • 173 citations

Inhibition of cytochrome c oxidase function by dicyclohexylcarbodiimide

1981 • 170 citations

Purified proton conductor in proton translocating adenosine triphosphatase of a thermophilic bacterium.

1977 • 159 citations

Membrane Proteins. The Amino Acid Composition of Membrane-Penetrating Segments

1981 • 157 citations

Cooperatively between catalytic sites in the mechanism of action of beef heart mitochondrial adenosine triphosphatase.

1981 • 157 citations

Exploring the adenine nucleotide binding sites on mitochondrial F1-ATPase with a new photoaffinity probe, 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate.

1982 • 153 citations

Subunit structure of adenosine triphosphatase. Comparison of the structure in thermophilic bacterium PS3 with those in mitochondria, chloroplasts, and Escherichia coli.

1979 • 144 citations

Proton Translocating ATPase of a Thermophilic Bacterium

1976 • 142 citations

The nucleotide sequence of the atp genes coding for the F0 subunits a, b, c and the F1 subunit δ of the membrane bound ATP synthase of Escherichia coli

1981 • 135 citations

The atp operon: nucleotide sequence of the region encoding the α-subunit of Escherichia coli ATP-synthase

1981 • 132 citations

Differential Effects of Adenylyl Imidodiphosphate on Adenosine Triphosphate Synthesis and the Partial Reactions of Oxidative Phosphorylation

1974 • 129 citations

Biochemistry and Genetics of Bacterial H+-Translocating ATPases

1981 • 123 citations

Reconstitution of thermostable ATPase capable of energy coupling from its purified subunits.

1977 • 122 citations

The synthesis of enzyme-bound ATP by soluble chloroplast coupling factor 1.

1982 • 122 citations

Origin of replication, oriC, of the Escherichia coli chromosome on specialized transducing phages λasn

1978 • 122 citations

Subunit interaction during catalysis. Alternating site cooperativity of mitochondrial adenosine triphosphatase.

1979 • 120 citations

Nucleotide sequence of the genes for β and ε subunits of proton-translocating ATPase from Escherichia coli

1982 • 119 citations

Subunits of the Adenosine Triphosphatase Complex Translated In Vitro from the Escherichia coli unc Operon

1980 • 118 citations

Identification of an essential glutamic acid residue in the beta subunit of the adenosine triphosphatase from the thermophilic bacterium PS3.

1981 • 118 citations

Properties and functions of the subunits of the Escherichia coli coupling factor ATPase

1981 • 114 citations

E. coli F1-ATPase interacts with a membrane protein component of a proton channel

1982 • 110 citations

The defective proton-ATPase of uncA mutants of Escherichia coli. Studies of nucleotide binding sites, bound aurovertin fluorescence, and labeling of essential residues of the purified F1-ATPase.

1981 • 110 citations

Nucleotide sequence of the genes coding for α, β and γ subunits of the proton-translocating ATPase of

1981 • 108 citations

Assessment of total catalytic sites and the nature of bound nucleotide participation in photophosphorylation.

1979 • 106 citations

Nucleotide sequence of the genes for F0 components of the proton-translocating ATPase from : Prediction of the primary structure of F0 subunits

1981 • 103 citations

The yeast mitochondrial adenosine triphosphatase complex. Subunit stoichiometry and physical characterization.

1980 • 103 citations

Energy coupling to ATP synthesis by the proton-translocating ATPase

1982 • 102 citations

The stereochemical course of phosphoric residue transfer catalyzed by beef heart mitochondrial ATPase.

1980 • 101 citations

Three genes coding for subunits of the membrane sector (F0) of the Escherichia coli adenosine triphosphatase complex

1981 • 100 citations

The isolated gamma subunit of Escherichia coli F1 ATPase binds the epsilon subunit.

1982 • 99 citations

Preparation and characterization of homogeneous coupling factor 6 from bovine heart mitochondria

1976 • 99 citations

The ATP Synthetase of Escherichia coli K12: Purification of the Enzyme and Reconstitution of Energy-Transducing Activities

1979 • 97 citations

A mutation affecting a second component of the F0 portion of the magnesium ion-stimulated adenosine triphosphatase of Escherichia coli K12. The uncC424 allele

1977 • 95 citations

Subunit equivalence in Escherichia coli and bovine heart mitochondrial F₁F₀ ATPases

1982 • 92 citations

Gene order and gene-polypeptide relationships of the proton-translocating ATPase operon (unc) of Escherichia coli.

1982 • 91 citations

The yeast mitochondrial ATPase complex. Subunit composition and evidence for a latent protease contaminant

1979 • 89 citations

Occurrence and significance of oxygen exchange reactions catalyzed by mitochondrial adenosine triphosphatase preparations.

1979 • 89 citations

Composition of complex V of the mitochondrial oxidative phosphorylation system.

1979 • 89 citations

The proteolipid of a mutant ATPase from Escherichia coli defective in H⁺‐conduction contains a glycine instead of the carbodiimide‐reactive aspartyl residue

1980 • 88 citations

Equilibrium binding of nucleotides to beef heart mitochondrial adenosine triphosphatase

1973 • 87 citations

On the subunit stoichiometry of the F1-ATPase and the sites in it that react specifically with p-fluorosulfonylbenzoyl-5'-adenosine.

1979 • 86 citations

Mu-induced polarity in the unc operon of Escherichia coli

1978 • 85 citations

Assembly of the adenosine triphosphatase complex in Escherichia coli: assembly of F0 is dependent on the formation of specific F1 subunits

1981 • 84 citations

Energy-transducing H+-ATPase of Escherichia coli. Reconstitution of proton translocation activity of the intrinsic membrane sector.

1980 • 83 citations

Identification of Amino‐Acid Substitutions in the Proteolipid Subunit of the ATP Synthase from Dicyclohexylcarbodiimide‐Resistant Mutants of Escherichia coli

1980 • 83 citations

Nucleotide Binding to Isolated Alpha and Beta Subunits of Proton Translocating Adenosine Triphosphatase Studied with Circular Dichroism1

1980 • 83 citations

Inactivation of the bovine mitochondrial F1-ATPase with dicyclohexyl[14C]carbodiimide leads to the modification of a specific glutamic acid residue in the beta subunit.

1981 • 81 citations

Bacteriophage lambda carrying the Escherichia coli chromosomal region of the replication origin.

1978 • 81 citations

Solid‐Phase Sequence Analysis of Polypeptides Eluted from Polyacrylamide Gels

1982 • 80 citations

Mitochondrial ATPase complex. A dispersed, cytochrome-deficient, oligomycin-sensitive preparation from rat liver containing molecules with a tripartite structural arrangement.

1979 • 79 citations

The uncA gene codes for the α-subunit of the adenosine triphosphatase of Escherichia coli. Electrophoretic analysis of uncA mutant strains

1979 • 77 citations

Regulation of the Synthesis and Hydrolysis of ATP in Biological Systems: Role of Peptide Inhibitors of H+-ATPases

1981 • 74 citations

Resolution of the membrane moiety of the H+-ATPase complex into two kinds of subunits.

1978 • 72 citations

Coupling Factor F1 ATPase with Defective β Subunit from a Mutant of Escherichia coli1

1980 • 71 citations

Structure of the mitochondrial F1 ATPase at 9-A resolution.

1982 • 71 citations

Specialized transducing phage lambda carrying the genes for coupling factor of oxidative phosphorylation of Escherichia coli: increased synthesis of coupling factor on induction of prophage lambda asn.

1979 • 71 citations

On the relationship between the oligomycin-sensitivity conferring protein and other mitochondrial coupling factors

1971 • 70 citations

Oxidative phosphorylation in Escherichia coli. Characterization of mutant strains in which F1-ATPase contains abnormal β-subunits

1983 • 67 citations

Reconstitution of Mitochondrial Oligomycin and Dicyclohexylcarbodiimide‐Sensitive ATPase

1980 • 67 citations

An Asp—Asn substitution in the proteolipid subnit of the ATP‐synthase from Escherichia coli leads to a non‐functional proton channel

1982 • 67 citations

Nucleotide sequence of genes coding for dicyclohexylcarbodiimide-binding protein and the α subunit of proton-translocating ATPase of Escherichia coli

1981 • 67 citations

Subunits of the H+-ATPase of Escherichia coli. Overproduction of an eight-subunit F1F0-ATPase following induction of a lambda-transducing phage carrying the unc operon.

1980 • 63 citations

Mitochondrial ATPase

1979 • 60 citations

Nucleotide sequence of the gene coding for the δ subunit of proton-translocating ATPase of Escherichia coli

1981 • 60 citations

ATP Synthetase (F₁F₀) of Escherichia coli K‐12

1982 • 58 citations

A model for membrane transport through α-helical protein pores

1978 • 58 citations

Differential polypeptide synthesis of the proton-translocating ATPase of Escherichia coli

1982 • 58 citations

ATP causes a large change in the conformation of the isolated alpha subunit of Escherichia coli F1 ATPase.

1980 • 57 citations

Adenosine triphosphatase from rat liver mitochondria: Separate sites involved in ATP hydrolysis and in the reversible, high affinity binding of ADP

1975 • 57 citations

Organization of unc gene cluster of Escherichia coli coding for proton-translocating ATPase of oxidative phosphorylation.

1980 • 54 citations

Reconstitution of oxidative phosphorylation and the adenosine triphosphate-dependent transhydrogenase activity by a combination of membrane fractions from uncA− and uncB− mutant strains of Escherichia coli K12

1973 • 54 citations

The isolated of F₀ of escherichia coli ATP‐synthase is reconstitutively active in H⁺‐conduction and ATP‐dependent energy‐transduction

1981 • 52 citations

Amino acid replacement in dicyclohexylcarbodiimide‐reactive proteins from mutant strains of escherichia coli defective in the energy‐ transducing ATPase complex

1980 • 50 citations

Tightly bound magnesium in mitochondrial adenosine triphosphatase from beef heart.

1979 • 47 citations

Genetic complementation between two mutant unc alleles (unc A401 and unc D409) affecting the F1 portion of the magnesium ion-stimulated adenosine triphosphatase of Escherichia coli K12

1978 • 47 citations

pH dependence of H+ conduction through the membrane moiety of the H+-ATPase (F0 . F1) and effects of tyrosyl residue modification.

1981 • 47 citations

4-Azido-2-nitrophenyl phosphate, a new photoaffinity derivative of inorganic phosphate. Study of its interaction with the inorganic phosphate binding site of beef heart mitochondrial adenosine triphosphatase

1980 • 47 citations

A Fifth Gene ( uncE ) in the Operon Concerned with Oxidative Phosphorylation in Escherichia coli

1979 • 46 citations

The genes for the eight subunits of the membrane bound ATP synthase of Escherichia coli

1981 • 45 citations

Tight divalent cation-binding sites of soluble adenosine triphosphatase (F1) from beef heart mitochondria and Escherichia coli.

1980 • 43 citations

Arrangement of oligomycin-sensitive adenosine triphosphatase in the mitochondrial inner membrane

1980 • 43 citations

Membrane mutation related to the production of extracellular α-amylase and protease in

1973 • 42 citations

Inhibition of proton conduction by chemical modification of the membrane moiety of proton translocating ATPase

1979 • 42 citations

Characterization of the mutant-unc D-gene product in a strain of Escherichia coli K12. An altered β-subunit of the magnesium ion-stimulated adenosine triphosphatase

1978 • 42 citations

Adenine nucleotide binding sites on beef heart F1-ATPase. Specificity of cooperative interactions between catalytic sites.

1982 • 41 citations

Purification and characterization of the inactive Ca2+, Mg2+-activated adenosine triphosphatase of the unc A− mutant Escherichia coli AN120

1977 • 40 citations

Resolution and reconstitution of complex V of the mitrochondrial oxidative phosphorylation system: Properties and composition of the membrane sector

1981 • 38 citations

Exploration of adenosine 5'-diphosphate-adenosine 5'-triphosphate binding sites of Escherichia coli adenosine 5'-triphosphatase with arylazido adenine nucleotides

1981 • 37 citations

Conversion of stable atpase to labile atpase by acetylation, and the αβ and αγ subunit complexes during its reconstitution

1981 • 37 citations

The proteolipid subunit of chloroplast adenosine triphosphatase complex. Mobility, accessibility, and interactions studied by a spin label technique.

1979 • 36 citations

Non-covalently bound adenine nucleotides in adenosine triphosphatase of

1976 • 36 citations

Demonstration and quantitation of catalytic and noncatalytic bound ATP in submitochondrial particles during oxidative phosphorylation.

1979 • 33 citations

Isolation, characterization, and reconstitution of a solubilized fraction containing the hydrophobic sector of the mitochondrial proton pump

1981 • 31 citations

The use of arylazido-beta-alanyl-ATP as a photoaffinity label for the isolated and membrane-bound mitochondrial ATPase complex.

1979 • 31 citations

The dicyclohexylcarbodiimide-binding protein c of ATP synthase from Escherichia coli is not sufficient to express an efficient H+ conduction.

1981 • 30 citations

[10] Isolation and characterization of mutants of Escherichia coli K-12 affected in oxidative phosphorylation or quinone biosynthesis

1979 • 29 citations

The uncoupler‐binding protein in the proton‐pumping ATPase from beef‐heart mitochondria

1981 • 27 citations

Structural gene coding for the dicyclohexylcarbodiimide‐binding protein of the proton‐translocating ATPase from escherichia coli

1981 • 26 citations

F₀ of Escherichia coli ATP‐synthase containing mutant and wild‐type carbodiimide‐binding proteins is impaired in H⁺‐conduction

1980 • 25 citations

The interaction of mitochondrial ATPase with an alkylating ATP‐analog

1977 • 25 citations

Beef heart mitochondrial adenosine triphosphatase-catalyzed formation of a transition state analog in ATP synthesis.

1980 • 23 citations

3′-Arylazido-8-azido ATP—A cross-linking photoaffinity label for ATP binding proteins

1980 • 23 citations

Effect of ATP on the translational diffusion coefficient of the α‐subunit of Escherichia coli F₁‐ATPase

1980 • 20 citations

Adenylylimidodiphosphate release from the active site of submitochondrial particles ATPase

1979 • 19 citations

Biogenesis of mitochondria. Defective assembly of the proteolipid into the mitochondrial adenosine triphosphatase complex in an oli2 mit− mutant of Saccharomyces cerevisiae

1981 • 19 citations

An active-site-directed adenosine triphosphate analogue binds to the β-subunits of factor F1 mitochondrial adenosine triphosphatase with its triphosphate moiety

1979 • 18 citations

Reaction Mechanism of the ATPase Activity of Mitochondrial Fi Studied by Using a Fluorescent ATP Analog, 2'-(5-Dimethyl-aminonaphthalene-1-Sulfonyl) Anuno-2'-DeoxyATP: Its Striking Resemblance to That of Myosin ATPase1

1981 • 14 citations

ATP‐synthetase complex (F₁F₀) from Escherichia coli

1982 • 11 citations

Trypsin cleavage of the α-subunit of beef heart F1-ATPase abolishes ATP synthesis and ATP-driven energy-transduction capabilities

1981 • 11 citations

Ion channels: structure and function.

1981 • 5 citations