Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.

Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

1995 • 1,960 citations

Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components

1994 • 972 citations

Jaks and Stats in signaling by the cytokine receptor superfamily

1995 • 902 citations

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

1995 • 760 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

1995 • 641 citations

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

1994 • 599 citations

Requirement for MAP Kinase (ERK2) Activity in Interferon α- and Interferon β-Stimulated Gene Expression Through STAT Proteins

1995 • 549 citations

Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity.

1995 • 374 citations

Interleukin-3 signals through multiple isoforms of Stat5.

1995 • 327 citations

Intermittent Plasma Growth Hormone Triggers Tyrosine Phosphorylation and Nuclear Translocation of a Liver-Expressed, Stat 5-related DNA Binding Protein.

1995 • 242 citations

Identification and purification of human stat proteins activated in response to interleukin-2

1995 • 223 citations

STF-IL-4: a novel IL-4-induced signal transducing factor.

1994 • 183 citations

Activation of Acute Phase Response Factor (APRF)/Stat3 Transcription Factor by Growth Hormone

1995 • 180 citations

Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor.

1994 • 179 citations

Mediation of Growth Hormone-dependent Transcriptional Activation by Mammary Gland Factor/Stat 5

1995 • 169 citations

Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver.

1995 • 139 citations

Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase.

1994 • 127 citations

Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland.

1993 • 110 citations

Prolactin-dependent activation of a tyrosine phosphorylated DNA binding factor in mouse mammary epithelial cells.

1994 • 82 citations

STAT3 and STAT5B Are Targets of Two Different Signal Pathways Activated by Hematopoietin Receptors and Control Transcription via Separate Cytokine Response Elements

1995 • 76 citations

Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells.

1994 • 75 citations

Mammary gland factor activated by prolactin on mammary epithelial cells and acute-phase response factor activated by interleukin-6 in liver cells share DNA binding and transactivation potential.

1994 • 65 citations

Growth Hormone Rapidly Activates Rat Serine Protease Inhibitor 2.1 Gene Transcription and Induces a DNA-Binding Activity Distinct from Those of Stat1, -3, and -4

1995 • 45 citations

Human growth hormone (GH) receptor is characterized as the 134-kilodalton tyrosine-phosphorylated protein activated by GH treatment in IM-9 cells.

1993 • 37 citations

The Identification of JAK2 Tyrosine Kinase as a Signaling Molecule for Growth Hormone

1994 • 30 citations

[4] Comparison of three methods for detecting tyrosine-phosphorylated photeins

1991 • 27 citations

Binding of a growth hormone-inducible nuclear factor is mediated by tyrosine phosphorylation.

1994 • 15 citations