A β-thalassemia ledon abolishes the sameMstII site as the sickle mutation

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

[49] DNA analysis in the diagnosis of hemoglobin disorders

1981 • 338 citations

Abnormal RNA processing due to the exon mutation of βE-globin gene

1982 • 309 citations

beta 0 thalassemia, a nonsense mutation in man.

1979 • 291 citations

Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

1981 • 236 citations

A Sensitive New Prenatal Test for Sickle-Cell Anemia

1982 • 201 citations

beta zero thalassemia in Sardinia is caused by a nonsense mutation.

1981 • 192 citations

Improved Detection of the Sickle Mutation by DNA Analysis

1982 • 171 citations

Nonsense and frameshift mutations in beta 0-thalassemia detected in cloned beta-globin genes.

1981 • 129 citations

High capacity gel preparative electrophoresis for purification of fragments of genomic DNA

1978 • 128 citations

An intron nucleotide sequence variant in a cloned β⁺-thalassaemia globin gene

1981 • 124 citations

ATA box transcription mutation inβ-thalassemia

1983 • 109 citations

beta-Thalassemia in a Kurdish Jew. Single base changes in the T-A-T-A box.

1982 • 106 citations

A nucleotide change at a splice junction in the human beta-globin gene is associated with beta 0-thalassemia.

1981 • 105 citations

Thalassemia Revisited

1982 • 96 citations

Hemoglobin Indianapolis (beta 112[G14] arginine). An unstable beta-chain variant producing the phenotype of severe beta-thalassemia.

1979 • 96 citations

"Silent" nucleotide substitution in a beta+-thalassemia globin gene activates splice site in coding sequence RNA.

1983 • 90 citations

Structure and expression of a cloned β°thalassaemic globin gene

1981 • 85 citations

Use of restriction endonucleases for mapping the allele for beta s-globin.

1982 • 78 citations

Structural analysis of a beta-thalassemia gene found in Taiwan.

1983 • 56 citations

Two cloned β thalassemia genes are associated with amber mutations at codon 39

1981 • 33 citations

Five nucleotide changes in the large intervening sequence of a β globin gene in a β⁺thalassemia patient

1982 • 32 citations

A sensitive test for prenatal diagnosis of sickle cell anemia: direct analysis of amniocyte DNA with MstII.

1982 • 12 citations