ATA box transcription mutation inβ-thalassemia

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences

1983 • 477 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

Abnormal RNA processing due to the exon mutation of βE-globin gene

1982 • 309 citations

β+ Thalassemia: Aberrant splicing results from a single point mutation in an intron

1981 • 235 citations

Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.

1980 • 195 citations

Abnormal RNA splicing causes one form of α thalassemia

1982 • 120 citations

beta-Thalassemia in a Kurdish Jew. Single base changes in the T-A-T-A box.

1982 • 106 citations

Evidence for multiple origins of the beta E-globin gene in Southeast Asia.

1982 • 103 citations

Abnormally spliced messenger RNA in erythroid cells from patients with β+ thalassemia and monkey cells expressing a cloned β+-thalassemic gene

1982 • 91 citations

Abnormal splice in a mutant human beta-globin gene not at the site of a mutation.

1983 • 80 citations

A T to A base substitution and small deletions in the conalbumin TATA box drastically decrease specific in vitro transcription

1981 • 64 citations

Point mutagenesis of the ovalbumin gene promoter sequence and its effect on in vitro transcription.

1982 • 49 citations