The sorting of proteins to the plasma membrane in epithelial cells.

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

Intracellular protein topogenesis

1980 • 1,378 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Receptor-mediated endocytosis

1985 • 577 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Asymmetric budding of viruses in epithelial monlayers: a model system for study of epithelial polarity.

1978 • 492 citations

Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances.

1981 • 424 citations

Vesicles and cisternae in the trans golgi apparatus of human fibroblasts are acidic compartments

1985 • 350 citations

Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA

1986 • 313 citations

Golgi membranes contain an electrogenic H+ pump in parallel to a chloride conductance.

1983 • 310 citations

Polarized distribution of viral envelope proteins in the plasma membrane of infected epithelial cells

1980 • 273 citations

pH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat.

1976 • 260 citations

Sorting of an apical plasma membrane glycoprotein occurs before it reaches the cell surface in cultured epithelial cells.

1984 • 247 citations

Viral glycoproteins destined for apical or basolateral plasma membrane domains traverse the same Golgi apparatus during their intracellular transport in doubly infected Madin-Darby canine kidney cells.

1984 • 228 citations

Intracellular sorting and polarized cell surface delivery of (Na+,K+)ATPase, an endogenous component of MDCK cell basolateral plasma membranes

1986 • 228 citations

Chloroquine diverts ACTH from a regulated to a constitutive secretory pathway in AtT-20 cells

1983 • 198 citations

Initial glycosylation and acidic pH in the Golgi apparatus are required for multimerization of von Willebrand factor.

1986 • 164 citations

Biogenesis of epithelial cell polarity: Intracellular sorting and vectorial exocytosis of an apical plasma membrane glycoprotein

1984 • 157 citations

An enzymatic assay reveals that proteins destined for the apical or basolateral domains of an epithelial cell line share the same late Golgi compartments.

1985 • 154 citations

Intracellular sorting and basolateral appearance of the G protein of vesicular stomatitis virus in Madin-Darby canine kidney cells.

1985 • 145 citations

Polarized delivery of viral glycoproteins to the apical and basolateral plasma membranes of Madin-Darby canine kidney cells infected with temperature-sensitive viruses.

1985 • 136 citations

Secretion of endogenous and exogenous proteins from polarized MDCK cell monolayers.

1986 • 132 citations

Exocytotic pathways exist to both the apical and the basolateral cell surface of the polarized epithelial cell MDCK

1985 • 121 citations

A single mutation in Chinese hamster ovary cells impairs both Golgi and endosomal functions.

1984 • 120 citations

Polarity of influenza and vesicular stomatitis virus maturation in MDCK cells: lack of a requirement for glycosylation of viral glycoproteins.

1979 • 115 citations

Glycosylation does not determine segregation of viral envelope proteins in the plasma membrane of epithelial cells.

1981 • 104 citations

Effect of lysosomotropic amines on the secretory pathway and on the recycling of the asialoglycoprotein receptor in human hepatoma cells.

1985 • 94 citations

Immunoelectron microscopic localization of acidic intracellular compartments in hepatoma cells.

1985 • 83 citations

Sorting and endocytosis of viral glycoproteins in transfected polarized epithelial cells.

1986 • 74 citations

Surface expression of influenza virus neuraminidase, an amino-terminally anchored viral membrane glycoprotein, in polarized epithelial cells.

1985 • 72 citations

Transepithelial transport of a viral membrane glycoprotein implanted into the apical plasma membrane of Madin-Darby canine kidney cells. II. Immunological quantitation.

1983 • 59 citations

Biosynthesis and intracellular sorting of growth hormone-viral envelope glycoprotein hybrids.

1985 • 50 citations

Surface Expression of Influenza Virus Neuraminidase, an Amino-Terminally Anchored Viral Membrane Glycoprotein, in Polarized Epithelial Cells

1985 • 29 citations