Physicochemical characterization of the nuclear form of Ah receptor from mouse hepatoma cells exposed in culture to 2,3,7,8-tetrachlorodibenzo-p-dioxin

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

1987 • 1,559 citations

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome

1988 • 1,007 citations

Identification of a new class of steroid hormone receptors

1988 • 845 citations

The P450 Gene Superfamily: Recommended Nomenclature

1987 • 812 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

1985 • 492 citations

Biochemistry, Molecular Biology, and Physiology of the Glucocorticoid Receptor*

1987 • 409 citations

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

1979 • 401 citations

The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins.

1986 • 392 citations

Activation, Transformation, and Subunit Structure of Steroid Hormone Receptors

1982 • 323 citations

A 59-kilodalton protein associated with progestin, estrogen, androgen, and glucocorticoid receptors

1986 • 261 citations

The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1987 • 251 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase by 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Evidence for a Receptor Mutation in Genetically Non-responsive Mice

1975 • 238 citations

Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines.

1980 • 227 citations

Activation of the glucocorticoid-receptor complex

1982 • 224 citations

The Molecular Mechanism of the in Vitro 4 S to 5 S Transformation of the Uterine Estrogen Receptor

1974 • 199 citations

Structure, dissociation, and proteolysis of mammalian steroid receptors. Multiplicity of glucocorticoid receptor forms and proteolytic enzymes in rat liver and kidney cytosols.

1983 • 197 citations

Transformation of glucocorticoid and progesterone receptors to the DNA‐binding state

1987 • 187 citations

The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

1982 • 184 citations

Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols.

1986 • 168 citations

Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones.

1982 • 160 citations

Photoaffinity labeling of the Ah receptor.

1986 • 139 citations

Dominant and recessive aryl hydrocarbon hydroxylase-deficient mutants of mouse hepatoma line, Hepa-1, and assignment of recessive mutants to three complementation groups

1983 • 124 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors in wild type and variant mouse hepatoma cells. Nuclear location and strength of nuclear binding.

1984 • 120 citations

Association of DNA-bound progesterone receptors

1987 • 116 citations

Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells.

1983 • 114 citations

Subunit composition of the molybdate-stabilized “8-9 S” nontransformed estradiol receptor purified from calf uterus.

1987 • 112 citations

Cytosolic and Nuclear Binding of 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin to the AhReceptor in Extra‐Hepatic Tissues of Rats and Mice

1982 • 103 citations

Molecular Mechanism of Steroid Hormone Action

1985 • 94 citations

Regulatory gene product of the Ah complex. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene binding to several moieties in mouse liver cytosol.

1981 • 92 citations

Binding of 3-Methylcholanthrene and 2,3,7,8-Tetrachlorodibenzo-p-dioxin to a Common Ah Receptor Site in Mouse and Rat Hepatic Cytosols

1982 • 90 citations

Stoichiometric analysis of the specific interaction of the glucocorticoid receptor with DNA.

1986 • 79 citations

The receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse hepatoma cell line Hepa 1c1c7. A comparison with the glucocorticoid receptor and the mouse and rat hepatic dioxin receptors.

1987 • 79 citations

Binding of benzo(a)pyrene and dibenz(a,h)anthracene to the Ah receptor in mouse and rat hepatic cytosols.

1984 • 77 citations

Rapid vertical tube rotor gradient assay for binding of 2,3,7,8-tetrachIorodibenzo-p-dioxin to the Ah receptor

1981 • 73 citations

Physicochemical characterization of specific and nonspecific polyaromatic hydrocarbon binders in rat and mouse liver cytosol.

1983 • 73 citations

Reversible dissociation of steroid hormone x receptor complexes by mercurial reagents.

1980 • 73 citations

Heterogeneity of the rat hepatic Ah receptor and evidence for transformation in vitro and in vivo.

1987 • 67 citations

The Ah receptor: Binding specificity only for foreign chemicals?

1984 • 65 citations

The role of sulfhydryl groups in permitting transformation and DNA binding of the glucocorticoid receptor.

1987 • 64 citations

Comparison of aryl hydrocarbon hydroxylase and acetanilide 4-hydroxylase induction by polycyclic aromatic compounds in human and mouse cell lines

1985 • 62 citations

Hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial stabilization by molybdate.

1986 • 54 citations

Ah receptor for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin

1986 • 43 citations

Aryl hydrocarbon hydroxylase induction in mammalian liver-derived cell cultures

1976 • 39 citations

Characterization of the DNA-binding properties of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin

1986 • 36 citations

Ribonucleic acid is a component of the oligomeric, transformed mouse AtT-20 cell glucocorticoid receptor

1985 • 35 citations

Intracellular location of the Ah receptor

1986 • 32 citations

High-affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cell nuclei from rat liver

1982 • 31 citations

The 1986 Bernard B. Brodie award lecture. The genetic regulation of drug-metabolizing enzymes.

1988 • 30 citations

Characterization of the in vitro stability of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

1987 • 27 citations

Structure and function of the Ah receptor: Sulfhydryl groups required for binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to cytosolic receptor from rodent livers

1987 • 25 citations

Protamine sulfate precipitation: A new assay for the Ah receptor

1984 • 18 citations

Examination and rapid analysis of hepatic cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using gel-permeation high performance liquid chromatography

1984 • 15 citations

Comparison of pyridoxal phosphate and 0.4 m KCl-extracted nuclear glucocorticoid receptors in HeLa S3 cells

1983 • 5 citations