Southern-blot analyses of human T-lymphocyte mutants induced in vitro by γ-irradiation

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Fine structure of the human hypoxanthine phosphoribosyltransferase gene.

1986 • 209 citations

The nature of mutants induced by ionising radiation in cultured hamster cells III. Molecular characterization of HPRT-deficient mutants induced by γ-rays or α-particles showing that the majority have deletions of all or part of the hprt gene

1986 • 207 citations

Molecular evidence for new mutation at the hprt locus in Lesch-Nyhan patients

1984 • 198 citations

Rearrangement of two distinct T-cell γ-chain variable-region genes in human DNA

1986 • 174 citations

In vivo somatic mutations in human lymphocytes frequently result from major gene alterations

1985 • 146 citations

Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes

1985 • 143 citations

Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

1978 • 126 citations

A three-allele restriction-fragment-length polymorphism at the hypoxanthine phosphoribosyltransferase locus in man.

1983 • 122 citations

Organization of the HPRT gene and related sequences in the human genome

1984 • 109 citations

Mutations induced by X-rays at the HPRT locus in cultured Chinese hamster cells are mostly large deletions

1985 • 100 citations

Expression of human and Chinese hamster hypoxanthine-guanine phosphoribosyltransferase cDNA recombinants in cultured Lesch-Nyhan and Chinese hamster fibroblasts.

1983 • 99 citations

Monitoring of Occupational Genotoxicants

1987 • 85 citations

Quantitative and Molecular Analyses of Radiation-Induced Mutation in AS52 Cells

1986 • 82 citations

Use of T-cell receptor gene probes to quantify the in vivo hprt mutations in human T-lymphocytes

1986 • 77 citations

Molecular analyses of in vivo hprt mutations in human T-lymphocytes I. Studies of low frequency ‘spontaneous’ mutants by Southern blots

1987 • 71 citations

Molecular and biochemical analyses of spontaneous and X-ray induced mutants in human lymphoblastoid cells

1987 • 63 citations

X-Ray Induction of 8-Azaguanine-Resistant Mutants in Synchronous Chinese Hamster Ovary Cells

1980 • 58 citations

Ionizing Radiation-Induced 6-Thioguanine-Resistant Clones in Synchronous CHO Cells

1980 • 53 citations

In vitro induction, expression and selection of thioguanine-resistant mutants with human T-lymphocytes

1990 • 53 citations

Molecular characterization of 15 rearrangements among 90 human in vivo somatic mutants shows that deletions predominate.

1987 • 53 citations

Exposure of nuclear medicine patients to ionizing radiation is associated with rises in HPRT− mutant frequency in peripheral T-lymphocytes

1987 • 48 citations

Molecular basis of X-ray-induced mutation at the HPRT locus in human lumphocytes

1986 • 47 citations

Molecular analyses of in vivo hprt mutant T cells from atomic bomb survivors

1989 • 43 citations

The nature of mutants by ionising radiation in cultured hamster cells

1984 • 31 citations

In vivo mutant frequency of technicians professionally exposed to ionizing radiation.

1986 • 29 citations

X-ray induction of 6-thioguanine-resistant mutants in division arrested, G0/G1 phase Chinese hamster ovary cells

1985 • 13 citations