Molecular analyses of in vivo hprt mutant T cells from atomic bomb survivors

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood.

1982 • 386 citations

Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types

1985 • 382 citations

Development and Function of Subpopulations of Thymocytes and T Lymphocytes

2015 • 296 citations

Measurement of in vivo mutations in human lymphocytes

1983 • 233 citations

THE WEIGHT OF THE THYMUS GLAND IN HEALTH AND IN DISEASE

1932 • 181 citations

Evidence for Increased Somatic Cell Mutations at the Glycophorin A Locus in Atomic Bomb Survivors

1987 • 180 citations

US-Japan Joint Reassessment of Atomic Bomb Radiation Dosimetry in Hiroshima and Nagasaki (Final Report)

1987 • 172 citations

Development and Function of Subpopulations of Thymocytes and T Lymphocytes (Part 1 of 2)

1975 • 168 citations

In vivo somatic mutations in human lymphocytes frequently result from major gene alterations

1985 • 146 citations

Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes

1985 • 143 citations

Mutation frequency in human lymphocytes increases with age

1984 • 138 citations

The structure of the T cell antigen receptor genes in normal and malignant T cells

1986 • 133 citations

The Effect of Changes in Dosimetry on Cancer Mortality Risk Estimates in the Atomic Bomb Survivors

1988 • 132 citations

Increased somatic cell mutant frequency in atomic bomb survivors

1988 • 117 citations

Organization of the HPRT gene and related sequences in the human genome

1984 • 109 citations

Measurement of spontaneous and X-irradiation-induced 6-thioguanine-resistant human blood lymphocytes using a T-cell cloning technique

1984 • 102 citations

Mutations induced by X-rays at the HPRT locus in cultured Chinese hamster cells are mostly large deletions

1985 • 100 citations

Monitoring of Occupational Genotoxicants

1987 • 85 citations

Quantitative and Molecular Analyses of Radiation-Induced Mutation in AS52 Cells

1986 • 82 citations

Detection of somatic mutations in man: evaluation of the microtitre cloning assay for T-lymphocytes

1986 • 80 citations

Mutations in human lymphocytes studied by an HLA selection system

1988 • 79 citations

Increased mutation frequency following treatment with cancer chemotherapy.

1985 • 78 citations

Use of T-cell receptor gene probes to quantify the in vivo hprt mutations in human T-lymphocytes

1986 • 77 citations

In vivo mutant frequency rises among breast cancer patients after exposure to high doses of γ-radiation

1985 • 77 citations

Molecular analyses of in vivo hprt mutations in human T-lymphocytes I. Studies of low frequency ‘spontaneous’ mutants by Southern blots

1987 • 71 citations

Mutations in human lymphocytes: Effect of X- and UV-irradiation

1984 • 56 citations

Measurement of in vivo HGPRT-deficient mutant cell frequency using a modified method for cloning human peripheral blood T-lymphocytes

1988 • 53 citations

Molecular characterization of 15 rearrangements among 90 human in vivo somatic mutants shows that deletions predominate.

1987 • 53 citations

Molecular basis of X-ray-induced mutation at the HPRT locus in human lumphocytes

1986 • 47 citations

Mutations in human lymphocytes effect of x irradiation and uv irradiation

1984 • 47 citations

In vivo mutant frequency of technicians professionally exposed to ionizing radiation.

1986 • 29 citations

An Assessment of the New Dosimetry for A-Bomb Survivors

1987 • 5 citations

Cancer Mortality

1986 • 5 citations