Fine structure of the human hypoxanthine phosphoribosyltransferase gene.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Genomic sequencing.

1984 • 8,343 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

1964 • 2,108 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells

1979 • 1,454 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Characterization of the human factor VIII gene

1984 • 983 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper

1980 • 760 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

The rate of spontaneous mutation of a human gene

1935 • 510 citations

Molecular cloning and characterization of the human β-like globin gene cluster

1980 • 452 citations

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

1984 • 435 citations

Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

1985 • 391 citations

The gene structure of human anti-haemophilic factor IX.

1984 • 361 citations

Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.

1985 • 329 citations

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

1984 • 305 citations

Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.

1983 • 299 citations

Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants

1982 • 295 citations

The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence

1984 • 272 citations

Signals regulating hepatitis B surface antigen transcription

1983 • 246 citations

The functional human dihydrofolate reductase gene.

1984 • 245 citations

Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

1984 • 226 citations

Isolation and Characterization of a Full-Length Expressible cDNA for Human Hypoxanthine Phosphoribosyltransferase

1983 • 222 citations

Human Bone Marrow Mesenchymal Stem Cell Behaviors on PCL/Gelatin Nanofibrous Scaffolds Modified with A Collagen IV-Derived RGD-Containing Peptide.

2014 • 215 citations

Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase

1984 • 203 citations

Molecular evidence for new mutation at the hprt locus in Lesch-Nyhan patients

1984 • 198 citations

Deletion and amplification of the HGPRT locus in Chinese hamster cells.

1983 • 147 citations

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency

1983 • 146 citations

Heterogeneity at the 5' termini of mouse dihydrofolate reductase mRNAs. Evidence for multiple promoter regions.

1985 • 145 citations

Sequences controlling in vitro transcription of SV40 promoters.

1983 • 139 citations

Cloned cDNA sequences of the hypoxanthine/guanine phosphoribosyltransferase gene from a mouse neuroblastoma cell line found to have amplified genomic sequences.

1982 • 136 citations

Propagation of some human DNA sequences in bacteriophage lambda vectors requires mutant Escherichia coli hosts.

1985 • 122 citations

Multiple mRNAs for 3-hydroxy-3-methylglutaryl coenzyme A reductase determined by multiple transcription initiation sites and intron splicing sites in the 5'-untranslated region.

1985 • 122 citations

A three-allele restriction-fragment-length polymorphism at the hypoxanthine phosphoribosyltransferase locus in man.

1983 • 122 citations

Analysis of the Mouse dhfr Promoter Region: Existence of a Divergently Transcribed Gene

1985 • 112 citations

Organization of the HPRT gene and related sequences in the human genome

1984 • 109 citations

Expression of human and Chinese hamster hypoxanthine-guanine phosphoribosyltransferase cDNA recombinants in cultured Lesch-Nyhan and Chinese hamster fibroblasts.

1983 • 99 citations

Human dihydrofolate reductase gene organization

1984 • 93 citations

Cytogenetics of the mammalian X chromosome. Part A. Basic mechanisms of X chromosome behavior.

1983 • 72 citations

Regional Localization of the Gene for Human Phosphoribosylpyrophosphate Synthetase on the X Chromosome

1979 • 64 citations

Comparative gene mapping: order of loci on the X chromosome is different in mice and humans.

1980 • 63 citations

SIMIAN VIRUS 40 AS A EUKARYOTIC CLONING VEHICLE

1981 • 63 citations

Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters.

1981 • 55 citations

Analysis of the mouse dhfr promoter region: existence of a divergently transcribed gene.

1985 • 52 citations

Deletion and Amplification of the HGPRT Locus in Chinese Hamster Cells

1983 • 46 citations

Isolation and characterisation of theXenopus laevisalbumin genes: loss of 74K albumin gene sequences by library amplification

1982 • 34 citations

Transcription of Adenovirus Type 2 Genes in a Cell-Free System: Apparent Heterogeneity of Initiation at Some Promoters

1981 • 25 citations

[37] Measurement of plasmid copy number

1979 • 21 citations

The Hypoxanthine Phosphoribosyltransferase Gene: A Model for the Study of Mutation in Mammalian Cells

1984 • 19 citations

Comparison of genomic fragment and clone sequences within a long interspersed repeated sequence of the mouse genome

1985 • 10 citations