Suppression of adenovirus E1A-induced apoptosis by mutated p53 is overcome by coexpression with Id proteins

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1993 • 875 citations

p53 and E2F-1 cooperate to mediate apoptosis.

1994 • 844 citations

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.

1994 • 772 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

Binding and modulation of p53 by p300/CBP coactivators

1997 • 698 citations

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis.

1993 • 677 citations

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.

1993 • 531 citations

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis.

1994 • 515 citations

Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids

1981 • 489 citations

The p300/CBP family: integrating signals with transcription factors and chromatin

1997 • 482 citations

Id helix—loop—helix proteins in cell growth and differentiation

1998 • 413 citations

The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein.

1994 • 371 citations

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

1995 • 361 citations

Rat cell line 3y1 and its virogenic polyoma‐ and SV40‐transformed derivatives

1975 • 340 citations

Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts.

1994 • 323 citations

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation.

1996 • 251 citations

Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins

1991 • 244 citations

Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

1990 • 224 citations

MyoD induces growth arrest independent of differentiation in normal and transformed cells.

1990 • 203 citations

Regulation of G1 progression by E2A and Id helix-loop-helix proteins.

1994 • 199 citations

Deregulated Expression of E2F-1 Induces S-Phase Entry and Leads to Apoptosis

1994 • 160 citations

Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors

1997 • 129 citations

Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis

1997 • 98 citations

Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block.

1994 • 90 citations

p300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis

1997 • 89 citations

Response of heat shock element within the human HSP70 promoter to mutated p53 genes.

1995 • 63 citations

E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins.

1993 • 56 citations

E1A-Mediated Inhibition of Myogenesis Correlates with a Direct Physical Interaction of E1A_12S and Basic Helix-Loop-Helix Proteins

1993 • 14 citations

Chromatin research gathers pace

1997 • 10 citations

Presence of p53 Mutations in 3Y1‐B Clone 1‐6: A Rat Cell Line Widely Used as a Normal Immortalized Fibroblast

1994 • 10 citations