Fibronectin synthesis in tubular epithelial cells: Up-regulation of the EDA splice variant by transforming growth factor β

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Genomic sequencing.

1984 • 8,343 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

1977 • 1,972 citations

CELL SURFACE INTERACTIONS WITH EXTRACELLULAR MATERIALS

1983 • 1,147 citations

Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage

1992 • 951 citations

The Progression of Renal Disease

1988 • 840 citations

Transforming growth factor-beta: recent progress and new challenges.

1992 • 781 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

1990 • 555 citations

Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat.

1989 • 489 citations

AMPLIFICATION OF RNA

1990 • 486 citations

TGF-β: Regulation of extracellular matrix

1992 • 485 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis

1994 • 413 citations

A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors.

1989 • 339 citations

Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon.

1987 • 334 citations

Plasma fibronectin is synthesized and secreted by hepatocytes.

1983 • 313 citations

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis.

1988 • 311 citations

Multiple sites of alternative splicing of the rat fibronectin gene transcript.

1987 • 299 citations

Mechanisms of tubulointerstitial fibrosis

1991 • 291 citations

Transforming Growth Factor β: Biochemistry and Roles in Embryogenesis, Tissue Repair and Remodeling, and Carcinogenesis

1988 • 255 citations

Regulation of fibronectin biosynthesis by dexamethasone, transforming growth factor beta, and cAMP in human cell lines.

1988 • 205 citations

Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed human cells.

1987 • 204 citations

Influence of Clinical and Histological Features on Actuarial Renal Survival in Adult Patients With Idiopathic IgA Nephropathy, Membranous Nephropathy, and Membranoproliferative Glomerulonephritis: Survey of the Recent Literature

1992 • 187 citations

Transforming growth factor β regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts

1988 • 185 citations

Isolation and characterization of cDNA clones for human and bovine fibronectins.

1983 • 184 citations

A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon.

1984 • 169 citations

Interstitial fibrosis in obstructive nephropathy

1993 • 166 citations

Stages of renal ontogenesis identified by monoclonal antibodies reactive with lymphohemopoietic differentiation antigens.

1983 • 160 citations

Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat.

1991 • 145 citations

Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis

1991 • 139 citations

Regulation of fibronectin biosynthesis by glucocorticoids in human fibrosarcoma cells and normal fibroblasts

1983 • 139 citations

Isolation, Culture and Characterization of Human Renal Tubular Cells

1985 • 115 citations

Molecular mechanisms of tubulointerstitial hypertrophy and hyperplasia

1991 • 111 citations

Human alveolar macrophage fibronectin: synthesis, secretion, and ultrastructural localization during gelatin-coated latex particle binding

1981 • 110 citations

Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues

1989 • 80 citations

The extracellular matrix in pathology.

1988 • 73 citations

Correlations between relative interstitial volume of the renal cortex and serum creatinine concentration in minimal changes with nephrotic syndrome and in focal sclerosing glomerulonephritis

1977 • 69 citations

Elements regulating an alternatively spliced exon of the rat fibronectin gene.

1993 • 62 citations

Role of proteoglycans and cytoskeleton in the effects of TGF-β1 on renal proximal tubule cells

1993 • 55 citations

Extracellular matrix accumulation in immune-mediated tubulointerstitial injury

1994 • 45 citations

Effects of epidermal growth factor on collagen synthesis by an epithelioid cell line derived from normal rat kidney.

1990 • 41 citations

Reversal by glucocorticoid hormones of the loss of a fibronectin and probollagen matrix around transformed human cells.

1979 • 40 citations

The Effect of Transforming Growth Factor β1 on Mesangial Cell Fibronectin Synthesis: Increased Incorporation into the Extracellular Matrix and Reduced pI but No Effect on Alternative Splicing

1993 • 33 citations

Fibronectin, the generation of multiple polypeptides from a single gene.

1986 • 29 citations

Specialized collagen mRNA and secreted collagens in human glomerular epithelial, mesangial, and tubular cells.

1992 • 28 citations

Regulation of plasma fibronectin biosynthesis by glucocorticoids in chick hepatocyte cultures.

1987 • 24 citations

The Role of Myofibroblasts in Renal Interstitial Fibrosis and Their Relationship with Fibronectin and Type IV Collagen

2015 • 17 citations

Flow kinetics of fibronectin secretion by livers of young preweanling rats.

1984 • 3 citations