Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Transforming growth factor-beta in disease: the dark side of tissue repair.

1992 • 1,126 citations

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1990 • 1,002 citations

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

1992 • 984 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage

1992 • 951 citations

The Progression of Renal Disease

1988 • 840 citations

Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations.

1990 • 838 citations

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

EXPERIMENTAL GLOMERULONEPHRITIS

1961 • 730 citations

Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species

1989 • 706 citations

RELATIONSHIP BETWEEN RENAL FUNCTION AND HISTOLOGICAL CHANGES FOUND IN RENAL-BIOPSY SPECIMENS FROM PATIENTS WITH PERSISTENT GLOMERULAR NEPHRITIS

1968 • 652 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

1990 • 555 citations

Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.

1986 • 542 citations

CHEMICAL PATHOLOGY

1975 • 495 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Tenascin: cDNA cloning and induction by TGF-beta.

1988 • 453 citations

Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta.

1986 • 443 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

Transforming growth factor-β regulates production of proteoglycans by mesangial cells

1990 • 365 citations

A COMPARATIVE HISTOLOGIC AND IMMUNOLOGIC STUDY IN RABBITS OF INDUCED HYPERSENSITIVITY OF THE SERUM SICKNESS TYPE

1953 • 321 citations

Mechanisms of tubulointerstitial fibrosis

1991 • 291 citations

Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat.

1986 • 262 citations

[Pathogenesis of serum sickness].

1959 • 252 citations

Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1

1992 • 248 citations

Quantitative and qualitative studies of antibody–induced mesangial cell damage in the rat

1987 • 204 citations

Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions.

1991 • 196 citations

ELEVATED EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA AND PROTEOGLYCAN PRODUCTION IN EXPERIMENTAL GLOMERULONEPHRITIS

1990 • 196 citations

Glomerular matrix accumulation is linked to inhibition of the plasmin protease system

1992 • 189 citations

Influence of Clinical and Histological Features on Actuarial Renal Survival in Adult Patients With Idiopathic IgA Nephropathy, Membranous Nephropathy, and Membranoproliferative Glomerulonephritis: Survey of the Recent Literature

1992 • 187 citations

Transforming growth factor β regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts

1988 • 185 citations

Proteinases and glomerular matrix turnover

1992 • 165 citations

Long-term prognosis of chronic idiopathic membranous glomerulonephritis. An analysis of 334 cases with particular regard to tubulo-interstitial changes.

1989 • 155 citations

Renal Disease: Classification and Atlas of Glomerular Diseases

1982 • 143 citations

Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis

1991 • 139 citations

Coordinated expression of beta 1 integrins and transforming growth factor-beta-induced matrix proteins in glomerulonephritis.

1993 • 137 citations

Platelet-complement interactions in mesangial proliferative nephritis in the rat.

1991 • 85 citations

Serum creatinine concentration and renal interstitial volume

1977 • 74 citations

The extracellular matrix in pathology.

1988 • 73 citations

Correlations between relative interstitial volume of the renal cortex and serum creatinine concentration in minimal changes with nephrotic syndrome and in focal sclerosing glomerulonephritis

1977 • 69 citations

Immune complex disease. I. Experimental acute and chronic glomerulonephritis.

1967 • 66 citations

Immunohistochemical analysis of extracellular components in the glomerular sclerosis of patients with glomerulonephritis.

1990 • 63 citations

No evidence for a specific role of IgM in mesangial proliferation of idiopathic nephrotic syndrome

1984 • 58 citations

The mesangium in anti-Thy-1 nephritis. Influx of macrophages, mesangial cell hypercellularity, and macromolecular accumulation.

1990 • 54 citations

Mesangial sclerotic change with persistent proteinuria in rats after two consecutive injections of monoclonal antibody 1–22–3

1992 • 45 citations

Relationship between glomerular lesions, serum creatinine and interstitial volume in membrano-proliferative glomerulonephritis

1977 • 41 citations

Identification of lymphohemopoietic cells in the kidneys of normal rats.

1986 • 25 citations

A rat model of progressive chronic glomerular sclerosis

1992 • 20 citations