Back to search

Time Window for Voluntary Exercise–Induced Increases in Hippocampal Neuroplasticity Molecules after Traumatic Brain Injury Is Severity Dependent

Data up to Jan 2025

Published2007
Citations169
References63

Total Citations Per Year

Abstract

References (63)

Running enhances neurogenesis, learning, and long-term potentiation in mice

1999 • 2,829 citations

Diffuse axonal injury and traumatic coma in the primate

1982 • 1,494 citations

CREB AND MEMORY

1998 • 1,421 citations

Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition

2004 • 1,345 citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

The New Neurometabolic Cascade of Concussion

2014 • 1,115 citations

CREB: A Major Mediator of Neuronal Neurotrophin Responses

1997 • 936 citations

Toward a molecular definition of long-term memory storage

1996 • 685 citations

Mild Head Injury Classification

1990 • 613 citations

Dynamic changes in local cerebral glucose utilization following cerebral concussion in rats: evidence of a hyper- and subsequent hypometabolic state

1991 • 571 citations

Neurotrophins and brain insults

1994 • 564 citations

Synapsins as mediators of BDNF-enhanced neurotransmitter release

2000 • 562 citations

Distinct pools of synaptic vesicles in neurotransmitter release

1995 • 526 citations

Lateral Fluid Percussion Brain Injury: A 15-Year Review and Evaluation

2005 • 512 citations

A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis

1999 • 510 citations

Voluntary exercise following traumatic brain injury: brain-derived neurotrophic factor upregulation and recovery of function

2004 • 473 citations

Differential effects of acute and chronic exercise on plasticity‐related genes in the rat hippocampus revealed by microarray

2002 • 433 citations

Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members

2001 • 431 citations

Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat

1990 • 411 citations

License to Run: Exercise Impacts Functional Plasticity in the Intact and Injured Central Nervous System by Using Neurotrophins

2005 • 409 citations

Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity

2003 • 374 citations

Early Microvascular and Neuronal Consequences of Traumatic Brain Injury: A Light and Electron Microscopic Study in Rats

1994 • 357 citations

Activation of the Supplementary Motor Area During Voluntary Movement in Man Suggests It Works as a Supramotor Area

1979 • 345 citations

GENE DISCOVERY INDROSOPHILA: New Insights for Learning and Memory

1998 • 344 citations

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

1993 • 344 citations

Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.

1995 • 333 citations

Sustained activation of hippocampal pyramidal cells by ‘space clamping’ in a running wheel

1999 • 321 citations

Regulation by synapsin I and Ca(2+)‐calmodulin‐dependent protein kinase II of the transmitter release in squid giant synapse.

1991 • 318 citations

Energy Dysfunction as a Predictor of Outcome after Moderate or Severe Head Injury: Indices of Oxygen, Glucose, and Lactate Metabolism

2003 • 286 citations

Positive and negative regulatory mechanisms that mediate long-term memory storage

1998 • 270 citations

The Neurochemical and Metabolic Cascade Following Brain Injury: Moving from Animal Models to Man

1995 • 226 citations

Traumatic Brain Injury in the Rat: Characterization of a Midline Fluid-Percussion Model

1987 • 224 citations

Exercise-Induced Changes in Local Cerebral Glucose Utilization in the Rat

1996 • 173 citations

The upregulation of plasticity-related proteins following TBI is disrupted with acute voluntary exercise

2004 • 171 citations

Recovery of Cognitive Function After Traumatic Brain Injury: A Multilevel Modeling Analysis of Canadian Outcomes

2008 • 164 citations

Methods for behavioral testing of spinal cord injured rats

2007 • 140 citations

Rapid Alterations of BDNF Protein Levels in the Rat Brain after Focal Ischemia: Evidence for Increased Synthesis and Anterograde Axonal Transport

1998 • 136 citations

Selective loss of hippocampal long-term potentiation, but not depression, following fluid percussion injury

1998 • 132 citations

Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus

2001 • 121 citations

Voluntary exercise or amphetamine treatment, but not the combination, increases hippocampal brain-derived neurotrophic factor and synapsin I following cortical contusion injury in rats

2008 • 116 citations

Relationship of depth of brain lesions to consciousness and outcome after closed head injury

1988 • 114 citations

Lateral fluid percussion injury in the developing rat causes an acute, mild behavioral dysfunction in the absence of significant cell death

2006 • 113 citations

Brain Insults in Rats Induce Increased Expression of the BDNF Gene through Differential Use of Multiple Promoters

1994 • 113 citations

Activity-dependent plasticity: implications for recovery after spinal cord injury

2008 • 107 citations

Uncoupling of local cerebral glucose metabolism and blood flow after acute fluid-percussion injury in rats

1997 • 106 citations

Experimental studies in head injury

1966 • 101 citations

Calcium regulation of the brain-derived neurotrophic factor gene

2000 • 97 citations

Regional distribution of cerebral blood flow during exercise in dogs

1980 • 91 citations

Injury-induced alterations in N-methyl-d-aspartate receptor subunit composition contribute to prolonged 45calcium accumulation following lateral fluid percussion

2004 • 88 citations

Alterations in BDNF and Synapsin I within the Occipital Cortex and Hippocampus after Mild Traumatic Brain Injury in the Developing Rat: Reflections of Injury-Induced Neuroplasticity

2002 • 84 citations

Models of brain injury and alterations in synaptic plasticity

2001 • 73 citations

Exercise normalizes levels of MAG and Nogo‐A growth inhibitors after brain trauma

2007 • 71 citations

Dynamics of synapsin I gene expression during the establishment and restoration of functional synapses in the rat hippocampus

1994 • 67 citations

Production and Distribution of Intracranial and Intraspinal Pressure Changes at Sudden Extradural Fluid Volume Input in Rabbits

1969 • 64 citations

Synaptic plasticity and the organization of behaviour after early and late brain injury.

1999 • 64 citations

Relationship between Intracranial Pressure and Cortical Spreading Depression following Fluid Percussion Brain Injury in Rats

2003 • 57 citations

Physiological consequences of morphologically detectable synaptic plasticity: potential uses for examining recovery following damage

2000 • 56 citations

Histopathologic Consequences of Moderate Concussion in an Animal Model: Correlations with Duration of Unconsciousness

1994 • 55 citations

Controlled contusion injury alters molecular systems associated with cognitive performance

2008 • 50 citations

Reduced plasma levels of tyrosine, precursor of brain catecholamines, and of essential amino acids in patients with severe traumatic brain injury after rehabilitation11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the authors(s) or upon any organization with which the author(s) is/are associated.

2003 • 35 citations

Experience: a double-edged sword for restorative neural plasticity after brain damage

2008 • 27 citations

Effects of Treadmill Exercise on Memory and Hippocampal BDNF Expression in Streptozotocin-induced Diabetic Rats

2007 • 3 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...