Curcuminoids Inhibit the Angiogenic Response Stimulated by Fibroblast Growth Factor-2, Including Expression of Matrix Metalloproteinase Gelatinase B

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Matrix Metalloproteinases

1999 • 3,774 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

1996 • 1,555 citations

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 • 1,421 citations

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

1995 • 1,352 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.

1994 • 550 citations

Involvement of Reactive Oxygen Species in Cytokine and Growth Factor Induction of c-fos Expression in Chondrocytes

1995 • 538 citations

Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κB

1998 • 500 citations

A model of angiogenesis in the mouse cornea.

1996 • 411 citations

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

1998 • 399 citations

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences

1996 • 351 citations

Plasminogen Activators and Matrix Metalloproteinases in Angiogenesis

1996 • 341 citations

Defective trophoblast function in mice with a targeted mutation of Ets2

1998 • 299 citations

v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.

1993 • 291 citations

Reactive Oxygen Species and Antioxidants in Signal Transduction and Gene Expression

2009 • 281 citations

Involvement of the Transcription Factor NF-κB in Tubular Morphogenesis of Human Microvascular Endothelial Cells by Oxidative Stress

1996 • 278 citations

The Pathophysiology of Angiogenesis

1995 • 269 citations

Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodelling cornea

1991 • 257 citations

Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.

1994 • 241 citations

Matrix metalloproteinase inhibition: A review of anti-tumour activity

1995 • 226 citations

Effect of dietary curcumin and dibenzoylmethane on formation of 7,12- dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice

1998 • 198 citations

Strategy and planning for chemopreventive drug development: Clinical development plans II

1996 • 192 citations

Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin

1991 • 186 citations

Mechanism of basement membrane dissolution preceding corneal ulceration.

1991 • 179 citations

The Genomic Response of Tumor Cells to Hypoxia and Reoxygenation

1995 • 178 citations

The Dietary Pigment Curcumin Reduces Endothelial Tissue Factor Gene Expression by Inhibiting Binding of AP-1 to the DNA and Activation of NF-κB

1997 • 165 citations

Transforming growth factor-beta and interleukin-1 modulate metalloproteinase expression by corneal stromal cells.

1991 • 163 citations

Curcumin Inhibits SK-Hep-1 Hepatocellular Carcinoma Cell Invasion in vitro and Suppresses Matrix Metalloproteinase-9 Secretion

1998 • 134 citations

Inhibition of Tissue Factor Gene Activation in Cultured Endothelial Cells by Curcumin

1997 • 127 citations

Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat

1995 • 121 citations

Basic Fribroblast Growth Factor Overexpression in Endothelial Cells: An Autocrine Mechanism for Angiogenesis and Angioproliferative Diseases

1998 • 109 citations

The rabbit gene for 92-kDa matrix metalloproteinase. Role of AP1 and AP2 in cell type-specific transcription.

1994 • 109 citations

Bioactive phytochemicals with emphasis on dietary practices.

1998 • 106 citations

Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein

1993 • 104 citations

A strategy to discover circulating angiogenesis inhibitors generated by human tumors.

1995 • 100 citations

Gelatinase B/lacZ Transgenic Mice, a Model for Mapping Gelatinase B Expression during Developmental and Injury-related Tissue Remodeling

1998 • 98 citations

The pattern of metalloproteinase expression by corneal fibroblasts is altered by passage in cell culture

1990 • 96 citations

Active and Tissue Inhibitor of Matrix Metalloproteinase-free Gelatinase B Accumulates within Human Microvascular Endothelial Vesicles

1998 • 87 citations

The role of NF-kappaB in the angiogenic response of coronary microvessel endothelial cells.

1996 • 72 citations

Inflammatory cytokines induce the expression of basic fibroblast growth factor (bFGF) isoforms required for the growth of Kaposiʼs sarcoma and endothelial cells through the activation of AP-1 response elements in the bFGF promoter

1998 • 68 citations

Regulation of Human Interstitial Collagenase (Matrix Metalloproteinase‐1) Promoter Activity by Fibroblast Growth Factor

1997 • 63 citations

Chemoprevention of Colon Cancer by Dietary Curcumin

1995 • 63 citations

Transcriptional regulation of basic fibroblast growth factor gene expression in capillary endothelial cells

1991 • 59 citations

A labile hyperphosphorylated c-Fos protein is induced in mouse fibroblast cells treated with a combination of phorbol ester and anti-tumor promoter curcumin

1995 • 27 citations