Sensitive assay for midazolam and its metabolite 1′-hydroxymidazolam in human plasma by capillary high-performance liquid chromatography

Midazolam: pharmacology and uses.

1985 • 900 citations

Midazolam

1985 • 717 citations

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*

1996 • 598 citations

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

1989 • 528 citations

Untitled

1992 • 437 citations

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily

1994 • 390 citations

Midazolam A Review of its Pharmacological Properties and Therapeutic Use

1984 • 355 citations

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

1994 • 350 citations

Pharmacokinetics and bioavailability of midazolam in man.

1983 • 286 citations

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.

1994 • 221 citations

Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite α-hydroxymidazolam in healthy volunteers

1992 • 214 citations

Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

1997 • 85 citations

Use of Probe Drugs as Predictors of Drug Metabolism in Humans

1997 • 83 citations

Determination of midazolam (versed®) and its metabolites in plasma by high-performance liquid chromatography

1985 • 56 citations

Simultaneous determination of midazolam and its three hydroxy metabolites in human plasma by electron-capture gas chromatography without derivatization

1989 • 45 citations

Midazolam determination by gas chromatography, liquid chromatography and gas chromatography—mass spectrometry

1982 • 37 citations

Determination of midazolam by high-performance liquid chromatography

1981 • 32 citations

Determination of midazolam and its metabolites in serum microsamples by high-performance liquid chromatography and its application to pharmacokinetics in rats

1996 • 24 citations

Rapid and sensitive high-performance liquid chromatographic assay for midazolam and 1-hydroxymidazolam, the major metabolite, in human serum

1988 • 22 citations

Rapid, sensitive determination of human serum midazolam by high-performance liquid chromatography

1990 • 9 citations