Midazolam A Review of its Pharmacological Properties and Therapeutic Use

Effect of Age, Gender, and Obesity on Midazolam Kinetics

1984 • 495 citations

Diazepam disposition determinants

1980 • 348 citations

Pharmacokinetics and bioavailability of midazolam in man.

1983 • 286 citations

Midazolam kinetics

1981 • 286 citations

Respiratory Depression by Midazolam and Diazepam

1980 • 273 citations

The pharmacokinetics of midazolam in man

1981 • 273 citations

Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat.

1976 • 211 citations

Rebound Insomnia: A New Clinical Syndrome

1978 • 201 citations

Rebound Insomnia and Rebound Anxiety: A Review

1983 • 198 citations

Hemodynamic Responses to Anesthetic Induction with Midazolam or Diazepam in Patients with Ischemic Heart Disease

1981 • 188 citations

Midazolam and diazepam in ketamine anaesthesia

1984 • 170 citations

Chemical structure and properties of midazolam compared with other benzodiazepines.

1983 • 164 citations

Comparative Evaluation of Intravenous Agents for Rapid Sequence Induction—Thiopental, Ketamine, and Midazolam

1982 • 157 citations

Pharmacology of midazolam.

1981 • 150 citations

Cardiovascular Responses to Diazepam and Midazolam Maleate in the Dog

1979 • 148 citations

The Pharmacokinetics of Midazolam in Chronic Renal Failure Patients

1983 • 147 citations

Early Morning Insomnia with Rapidly Eliminated Benzodiazepines

1983 • 139 citations

Amnesic action of midazolam

1980 • 131 citations

Clinical, Electroencephalographic, and Pharmacokinetic Studies of a Water-soluble Benzodiazepine, Midazolam Maleate

1979 • 125 citations

Excretion and metabolism of 14C-midazolam in humans following oral dosing.

1981 • 117 citations

Comparison of two benzodiazepines for anaesthesia induction: midazolam and diazepam

1978 • 115 citations

Concentration-independent plasma protein binding of benzodiazepines

1983 • 115 citations

Relationship between plasma concentration and effect of midazolam after oral and intravenous administration.

1983 • 112 citations

Evaluation of midazolam as an intravenous induction agent

1981 • 112 citations

TESTS OF RECOVERY FROM ANAESTHESIA AND SEDATION: INTRAVENOUS DIAZEPAM IN DENTISTRY

1973 • 106 citations

COMPARISON OF MIDAZOLAM AND DIAZEPAM IN DOSES OF COMPARABLE POTENCY DURING GASTROSCOPY

1983 • 104 citations

A RANDOMIZED COMPARISON OF MIDAZOLAM AND DIAZEPAM FOR SEDATION IN UPPER GASTROINTESTINAL ENDOSCOPY

1983 • 104 citations

Anterograde amnesic effects of pethidine, hyoscine and diazepam in adults

1972 • 103 citations

A Water-soluble Benzodiazepine, RO 21–3981, for Induction of Anesthesia

1978 • 103 citations

Midazolam: a water‐soluble benzodiazepine

1980 • 103 citations

Hypnotic Efficacy of Triazolam: Sleep Laboratory Evaluation of Intermediate‐Term Effectiveness

1976 • 99 citations

Midazolam maleate induction in patients with ischaemic heart disease: Haemodynamic observations

1979 • 98 citations

Physiologie and temporal variation in hepatic elimination of midazolam

1982 • 96 citations

Sequelae after the intravenous injection of three benzodiazepines--diazepam, lorazepam, and flunitrazepam.

1977 • 95 citations

Preclinical pharmacology of midazolam.

1983 • 95 citations

Automated Gas Chromatography for Studies of Midazolam Pharmacokinetics

1981 • 94 citations

I.V. MIDAZOLAM AS AN INDUCTION AGENT FOR ANAESTHESIA: A STUDY IN VOLUNTEERS

1980 • 94 citations

Midazolam, a new more potent benzodiazepine, compared with diazepam: a randomized, double-blind study of preendoscopic sedatives

1983 • 93 citations

RO 21???3981 for Intravenous Surgical Premedication and Induction of Anesthesia

1978 • 92 citations

CLINICAL STUDIES OF INDUCTION AGENTS XXV: DIAZEPAM

1968 • 90 citations

IN VITRO QUANTITATION OF BENZODIAZEPINE LIPOPHILICITY: RELATION TO IN VIVO DISTRIBUTION

1983 • 88 citations

Physiological and pharmacological variability in estimated hepatic blood flow in man.

1981 • 86 citations

Time Course of Ventilatory Depression after Thiopental and Midazolam in Normal Subjects and in Patients with Chronic Obstructive Pulmonary Disease

1983 • 84 citations

THE BENZODIAZEPINES: A review of their actions and uses relative to anaesthetic practice

1970 • 79 citations

Comparative Cardiovascular Effects of Midazolam and Thiopental in Healthy Patients

1982 • 78 citations

Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease

1977 • 75 citations

The effect of triazolam on the sleep of insomniacs

1975 • 73 citations

Respiratory Depressant Effects of Different Doses of Midazolam and Lack of Reversal with Naloxone-A Double-Blind Randomized Study

1983 • 72 citations

FREQUENCY OF PAIN ON INJECTION AND VENOUS SEQUELAE FOLLOWING THE I.V. ADMINISTRATION OF CERTAIN ANAESTHETICS AND SEDATIVES

1982 • 71 citations

Effects of loprazolam and of triazolam on sleep and overnight urinary cortisol

1984 • 71 citations

Midazolam and diazepam for gastroscopy

1982 • 60 citations

HAEMODYNAMIC RESPONSES TO INDUCTION OF ANAESTHESIA USING MIDAZOLAM IN CARDIAC SURGICAL PATIENTS

1982 • 59 citations

Placental transfer and maternal midazolam kinetics

1983 • 57 citations

Physostigmine Reversal of Midazolam-induced Sedation

1982 • 56 citations

Quantitation by Gas Chromatography of the 1- and 4-Hydroxy Metabolites of Midazolam in Human Plasma

1984 • 54 citations

Intravenous sedation for upper gastrointestinal endoscopy: diazepam versus midazolam.

1984 • 53 citations

Pharmacokinetics of benzodiazepines. Short-acting versus long-acting.

1980 • 51 citations

HAEMODYNAMIC EFFECTS OF MIDAZOLAM AND THIOPENTONE DURING INDUCTION OF ANAESTHESIA FOR CORONARY ARTERY SURGERY

1982 • 50 citations

COMPARISON OF THE I.V. ADMINISTRATION OF MIDAZOLAM AND DIAZEPAM AS SEDATION DURING SPINAL ANAESTHESIA

1983 • 48 citations

Midazolam: Dose-Response Studies of Effectiveness and Rebound Insomnia

1983 • 47 citations

Intravenous Benzodiazepines as Anaesthetic Agents: Pharmacokinetics and Clinical Consequences

1982 • 43 citations

Midazolam in dentistry

1983 • 43 citations

Triazolam and anterograde amnesia: all is not well in the Z-zone.

1983 • 42 citations

Midazolam kinetics in women of two age groups

1983 • 42 citations

A Bioassay of a Water-soluble Benzodiazepine Against Sodium Thiopental

1980 • 42 citations

Intracranial Pressure, Mean Arterial Pressure, and Heart Rate Following Midazolam or Thiopental in Humans with Brain Tumors

1984 • 41 citations

Circulatory Responses to Midazolam Anesthesia

1983 • 40 citations

Ranitidine influences the uptake of oral midazolam.

1983 • 40 citations

Midazolam versus hydroxyzine as intramuscular premedicant

1983 • 39 citations

EFFECT OF DIFFERENT KINDS OF PREMEDICATION ON THE INDUCTION PROPERTIES OF MIDAZOLAM

1982 • 39 citations

[A microprocessor controlled infusion scheme for midazolam to achieve constant plasma levels (author's transl)].

1982 • 37 citations

Midazolam determination by gas chromatography, liquid chromatography and gas chromatography—mass spectrometry

1982 • 37 citations

Factors influencing diazepam pharmacokinetics: age, sex, and liver disease.

1978 • 35 citations

Cardiovascular response to intubation

1983 • 35 citations

Efficacy and safety of midazolam in the treatment of night terrors in children.

1983 • 34 citations

VENOUS COMPLICATIONS AFTER I.V. ADMINISTRATION OF DIAZEMULS (DIAZEPAM) AND DORMICUM (MIDAZOLAM)

1981 • 33 citations

Determination of midazolam by high-performance liquid chromatography

1981 • 32 citations

COMPARISON BETWEEN MIDAZOLAM AND THIOPENTONE-BASED BALANCED ANAESTHESIA FOR DAY-CASE SURGERY

1984 • 32 citations

Simultaneous determination and pharmacokinetics of midazolam and its hydroxymetabolites in plasma and urine of man and dog by means of high-performance liquid chromatography.

1981 • 30 citations

Pharmacokinetics and Sedative Effect of Midazolam in Connection with Caesarean Section Performed Under Epidural Analgesia

1984 • 30 citations

Pain and clinical thrombophlebitis following intravenous diazepam and lorazepam

1978 • 29 citations

Sleep laboratory study of the effects of midazolam in insomniac patients

1982 • 29 citations

Haemodynamic Effects of Midazolam in the Anaesthetized Patient with Coronary Artery Disease

1983 • 29 citations

The effects of midazolam in conjunction with alcohol on sleep, psychomotor performance and car driving ability.

1983 • 29 citations

USE OF MIDAZOLAM AS AN INDUCTION AGENT: COMPARISON WITH THIOPENTONE

1982 • 28 citations

Midazolam versus atropine plus pethidine as premedication in children

1984 • 28 citations

Midazolam Compared with Thiopentone as an Induction Agent

1982 • 27 citations

Midazolam in Paediatric Anaesthesia

1982 • 27 citations

The Effects of Midazolam in Conjunction with Alcohol on Iconic Memory and Free-Recall

1983 • 27 citations

[Relation between the clinical effect and the pharmacokinetics of midazolam following i.m. and i.v. administration/2nd comm.: Pharmacokinetical aspects (author's transl)].

1981 • 26 citations

CSF penetration and pharmacokinetics of midazolam

1983 • 25 citations

Midazolam for Induction of Anaesthesia in Outpatients: A Comparison with Thiopentone

1981 • 24 citations

Midazolam for upper gastrointestinal endoscopy.

1984 • 24 citations

Effect of a water soluble benzodiazepine on the responses of spinal neurones to acetylcholine and excitatory amino acid analogues

1978 • 24 citations

Effect of midazolam on sleep of insomniacs.

1983 • 21 citations

Midazolam: effects on psychomotor performance and subjective aspects of sleep and sedation in normal volunteers.

1983 • 21 citations

Comparative haemodynamic and respiratory effects of midazolam and flunitrazepam as induction agents in cardiac surgery.

1981 • 21 citations

ACUTE “TOLERANCE” TO THE CENTRAL RESPIRATORY EFFECTS OF MIDAZOLAM IN THE DOG

1982 • 19 citations

Anesthetic Techniques for Cystoscopy in Men

1983 • 19 citations

Biotransformation of [¹⁴C]midazolam in the ratin vitroandin vivo

1981 • 19 citations

Histopathology of veins after intravenous lorazepam and ro 21-3981

1978 • 18 citations

Effect of midazolam on sleep.

1983 • 18 citations

Midazolam: sleep and performance studies in middle age.

1983 • 17 citations

Comparison of midazolam and flunitrazepam for night sedation

1982 • 17 citations

[Pharmacokinetics of midazolam after i.v. administration (author's transl)].

1981 • 17 citations

Use of atropine in connection with oral midazolam premedication.

1984 • 15 citations

Pharmacokinetic and clinical considerations in the choice of a hypnotic.

1983 • 15 citations

Influence of serum protein, serum albumin concentrations and dose on midazolam anaesthesia induction times

1981 • 15 citations

Midazolam versus diazepam: different effects on systemic vascular resistance. A randomized study utilizing cardiopulmonary bypass constant flow.

1981 • 15 citations

Midazolam and Fat‐Emulsion Diazepam as Intramuscular Premedication A Double‐Blind Clinical Trial

1983 • 15 citations

Effect of midazolam, flunitrazepam, and placebo against midwinter insomnia in northern Norway

1983 • 14 citations

Liver enzyme studies with disoprofol (ICI 35,868) and midazolam

1982 • 14 citations

[Pharmacokinetics of midazolam in man (author's transl)].

1981 • 14 citations

MIDAZOLAM EFFICACY FOR INTRAMUSCULAR PREMEDICATION

1982 • 14 citations

Sleep laboratory and performance evaluation of midazolam in insomniacs.

1983 • 13 citations

CLINICAL STUDIES OF INDUCTION AGENTS XLIII: FLUNITRAZEPAM

1976 • 13 citations

Midazolam in the treatment of sleep disorders in geriatric patients.

1983 • 12 citations

Midazolam for the Intravenous Induction of Anaesthesia in Children

1982 • 11 citations

Comparison of thiopentone and midazolam for induction of anaesthesia: Influence of diazepam premedication

1982 • 10 citations

Comparative clinical studies with midazolam, oxazepam and placebo.

1983 • 10 citations

Effects of midazolam on sleep in normal subjects.

1983 • 10 citations

Efficacy and safety of midazolam and vesparax in treatment of sleep disorders.

1983 • 10 citations

SEDATION AND RESPIRATORY MECHANICS IN MAN

1983 • 10 citations

Computerized analysis of sleep recordings applied to drug evaluation: Midazolam in normal subjects

1981 • 9 citations

Hypnotic efficacy and clinical safety of midazolam in shift‐workers.

1983 • 9 citations

Intramuscular and oral midazolam. Some factors influencing uptake

1983 • 9 citations

Midazolam and triazolam in out‐patients: a double‐blind comparison of hypnotic efficacy.

1983 • 9 citations

Midazolam/fentanyl. A total intravenous technique for short procedures

1982 • 9 citations

[Episodes of anterograde amnesia associated with the use of triazolam].

1980 • 9 citations

Cardiovascular changes during intubation with midazolam as anaesthesia inducing agent.

1981 • 9 citations

Automatic scoring of polygraphic sleep recordings: midazolam in insomniacs.

1983 • 9 citations

Effects of midazolam on sleep in normal subjects.

1983 • 8 citations

Midazolam and oxazepam in the treatment of insomnia in hospitalized patients.

1983 • 8 citations

Evaluation of the efficacy and tolerance of orally administered midazolam as hypnotic agent compared with oxazepam in the treatment of insomnia of mild to moderate severity.

1981 • 8 citations

Midazolam dosage studies in institutionalized geriatric patients.

1983 • 8 citations

Midazolam as a sedative on regional anesthesia. Preliminary results.

1981 • 7 citations

Evaluation of efficacy and safety of midazolam administered orally in sleep disorders. A dose-finding study.

1981 • 7 citations

[Haemodynamic effects and characteristics of midazolam during induction of anesthesia (author's transl)].

1981 • 7 citations

Comparison of midazolam with thiopentone for outpatient anaesthesia.

1983 • 7 citations

Assay of midazolam and brotizolam in plasma by a gas chromatographic and a radioreceptor technique

1983 • 7 citations

Awakening characteristics following anesthesia induction with midazolam for short surgical procedures.

1981 • 6 citations

Hypnotic efficacy and safety of midazolam and oxazepam in hospitalized female patients.

1983 • 6 citations

[Respiratory and sleep-inducing effects of i.m. midazolam as premedication for regional anesthesia. Comparison with diazepam, promethazine/pethidine and placebo].

1983 • 6 citations

Efficacy and safety of midazolam and oxazepam in insomniacs.

1983 • 6 citations

[The effects of midazolam on the general, coronary and cerebral circulation (author's transl)].

1980 • 6 citations

Comparative study of midazolam and vesparax in moderate or severe insomnia in female surgical patients.

1983 • 4 citations

[Comparative study of the effect of midazolam and hypnomidate on the cardiovascular system].

1983 • 3 citations

[A double-blind study of the effects of midazolam on sleep prior to surgery (author's transl)].

1981 • 3 citations

[Comparative study of thiopental and midazolam for induction of anesthesia].

1983 • 3 citations

Some observations on the use of midazolam in conscious sedation.

1984 • 1 citations