Defective regulation of phosphatidylcholine-specific phospholipases C and D in a kindred with Tangier disease. Evidence for the involvement of phosphatidylcholine breakdown in HDL-mediated cholesterol efflux mechanisms.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

High-Density Lipoprotein — The Clinical Implications of Recent Studies

1989 • 1,565 citations

Heterotrimeric C proteins: Organizers of transmembrane signals

1995 • 1,388 citations

Circulating and Tissue Endothelin Immunoreactivity in Advanced Atherosclerosis

1991 • 967 citations

Diglyceride lipase: a pathway for arachidonate release from human platelets.

1979 • 696 citations

Mechanisms and consequences of cellular cholesterol exchange and transfer

1987 • 547 citations

The picomole determination of free and total cholesterol in cells in culture.

1978 • 440 citations

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease.

1995 • 416 citations

Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes.

1988 • 307 citations

Characterization of proteoliposomes containing apoprotein A-I: a new substrate for the measurement of lecithin: cholesterol acyltransferase activity.

1982 • 300 citations

Regulation of high density lipoprotein receptor activity in cultured human skin fibroblasts and human arterial smooth muscle cells.

1983 • 276 citations

Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins

1988 • 275 citations

Tangier Disease

1961 • 264 citations

Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol

1991 • 259 citations

Homozygous Tangier disease and cardiovascular disease

1994 • 257 citations

Chemically induced lipid phase separation in model membranes containing charged lipids: A spin label study

1975 • 239 citations

Identification and characterization of a high density lipoprotein-binding protein in cell membranes by ligand blotting.

1987 • 215 citations

Metabolism of High-Density Lipoprotein Apolipoproteins in Tangier Disease

1978 • 199 citations

Phospholipase D

1978 • 190 citations

Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture. Patterns of acetylcholine phosphocholine, and choline phosphoglycerides labeling from (methyl-14C)choline.

1976 • 164 citations

Phospholipase D and cell signaling

1993 • 161 citations

Binding of high density lipoprotein to cultured fibroblasts after chemical alteration of apoprotein amino acid residues.

1986 • 122 citations

HDL-Mediated Efflux of Intracellular Cholesterol Is Impaired in Fibroblasts From Tangier Disease Patients

1995 • 120 citations

Tangier disease: a disorder of intracellular membrane traffic.

1985 • 112 citations

The lipoprotein abnormality in Tangier disease: quantitation of A apoproteins.

1977 • 108 citations

Structural analysis of human apolipoprotein A-I variants. Amino acid substitutions are nonrandomly distributed throughout the apolipoprotein A-I primary structure.

1990 • 105 citations

Phospholipid metabolism in bradykinin-stimulated human fibroblasts. II. Phosphatidylcholine breakdown by phospholipases C and D; involvement of protein kinase C

1991 • 100 citations

A tumour promoter, 12-O-tetradecanoylphorbol 13-acetate, increases cellular 1,2-diacylglycerol content through a mechanism other than phosphoinositide hydrolysis in Swiss-mouse 3T3 fibroblasts

1987 • 93 citations

Propranolol-induced inhibition of rat brain cytoplasmic phosphatidate phosphohydrolase

1983 • 92 citations

Isolation and Characterization of an Abnormal High Density Lipoprotein in Tangier Disease

1977 • 84 citations

Alpha 2-C10 adrenergic receptors expressed in rat 1 fibroblasts can regulate both adenylylcyclase and phospholipase D-mediated hydrolysis of phosphatidylcholine by interacting with pertussis toxin-sensitive guanine nucleotide-binding proteins.

1992 • 84 citations

The High Density Lipoprotein- and Apolipoprotein A-I-Induced Mobilization of Cellular Cholesterol Is Impaired in Fibroblasts from Tangier Disease Subjects

1994 • 79 citations

Characterization of high density lipoproteins in patients heterozygous for Tangier disease.

1977 • 61 citations

HDL₃Stimulates Multiple Signaling Pathways in Human Skin Fibroblasts

1995 • 58 citations

In vivo metabolism of proapolipoprotein A-I in Tangier disease.

1987 • 55 citations

Endothelin receptors stimulate both phospholipase C and phospholipase D activities in different cell lines

1993 • 51 citations

Abnormal processing of Golgi elements and lysosomes in Tangier disease.

1991 • 49 citations

Up-regulation of high density lipoprotein receptor activity by gamma-interferon associated with inhibition of cell proliferation.

1988 • 46 citations

Dysregulation of lipid metabolism in Tangier monocyte-derived macrophages.

1990 • 40 citations

Epidermal-growth-factor-induced production of phosphatidylalcohols by HeLa cells and A431 cells through activation of phospholipase D

1992 • 39 citations

Apoprotein a metabolism in tangier disease

1978 • 39 citations

Human proapoA-ITangier: Isolation of proapoA-ITangier and amino acid sequence of the propeptide

1983 • 32 citations

The Heart in Tangier Disease: Severe Coronary Atherosclerosis with Near Absence of High-Density Lipoprotein Cholesterol

1992 • 30 citations

Activation of Phosphatidylinositol-Specific Phospholipase C in Response to HDL ₃ and LDL Is Markedly Reduced in Cultured Fibroblasts From Tangier Patients

1995 • 27 citations

High density lipoprotein infusion and partial plasma exchange in Tangier disease

1978 • 24 citations

Haemolytic anaemia in analpha‐lipoproteinaemia (Tangier disease): morphological, biochemical, and biophysical properties of the red blood cell

1989 • 22 citations

Characterization of atherosclerosis in a patient with familial high-density lipoprotein deficiency

1994 • 13 citations

Activation of Phosphatidylinositol-Specific Phospholipase C in Response to HDL3 and LDL Is Markedly Reduced in Cultured Fibroblasts From Tangier Patients

1995 • 1 citations

HDL3 Stimulates Multiple Signaling Pathways in Human Skin Fibroblasts

1995 • 1 citations