Proteolytic processing of the 72,000-Da type IV collagenase by urokinase plasminogen activator

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

1987 • 625 citations

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase.

1985 • 625 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

1991 • 509 citations

Proteolytic degradation of extracellular matrix in tumor invasion

1987 • 484 citations

Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression

1991 • 461 citations

Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta.

1986 • 443 citations

Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts

1990 • 428 citations

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis

1988 • 354 citations

The Activation of Human Type IV Collagenase Proenzyme

1989 • 347 citations

Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.

1991 • 343 citations

Growth factors in the regulation of pericellular proteolysis: a review.

1989 • 342 citations

Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts.

1988 • 312 citations

Structure of the human type IV collagenase gene.

1990 • 310 citations

Isolation of the pericellular matrix of human fibroblast cultures.

1979 • 302 citations

Transforming growth factor-beta induction of type-1 plasminogen activator inhibitor. Pericellular deposition and sensitivity to exogenous urokinase.

1987 • 263 citations

Secretion of basement membrane collagen degrading enzyme and plasminogen activator by transformed cells – role in metastasis

1982 • 195 citations

Production of gelatin-degrading matrix metalloproteinases (‘type IV collagenases’) and inhibitors by articular chondrocytes during their dedifferentiation by serial subcultures and under stimulation by interleukin-1 and tumor necrosis factor α

1991 • 127 citations

Growth factor control of extracellular proteolysis

1990 • 104 citations

Human gelatinase/type IV procollagenase is a regular plasma component

1989 • 79 citations

The cellular target for the plasminogen activator, urokinase, in human fibroblasts - 66 000-dalton protein

1982 • 71 citations

A gelatin-binding 70,000-dalton glycoprotein synthesized distinctly from fibronectin by normal and malignant adherent cells.

1981 • 64 citations

Human plasma fibronectin as a substrate for human urokinase

1989 • 58 citations

Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin

1988 • 51 citations

Thrombin affects fibronectin and procollagen in the pericellular matrix of cultured human fibroblasts

1981 • 30 citations

Specific effects of fibronectin-releasing peptides on the extracellular matrices of cultured human fibroblasts.

1980 • 20 citations