Checkpoint signaling: Epigenetic events sound the DNA strand‐breaks alarm to the ATM protein kinase

The fundamental role of epigenetic events in cancer

2002 • 5,532 citations

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

2003 • 3,385 citations

The DNA damage response: putting checkpoints in perspective

2000 • 3,147 citations

ATM and related protein kinases: safeguarding genome integrity

2003 • 2,516 citations

Cell Cycle Checkpoints: Preventing an Identity Crisis

1996 • 2,056 citations

Cell cycle checkpoint signaling through the ATM and ATR kinases

2001 • 1,962 citations

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

1998 • 1,734 citations

DNA damage induces phosphorylation of the amino terminus of p53

1997 • 829 citations

ATM and ATR: networking cellular responses to DNA damage

2001 • 595 citations

When is a lipid kinase not a lipid kinase? When it is a protein kinase

1995 • 315 citations

Methods for the Quantification of DNA Double-Strand Breaks Determined from the Distribution of DNA Fragment Sizes Measured by Pulsed-Field Gel Electrophoresis

1995 • 92 citations

ATP Activates Ataxia-Telangiectasia Mutated (ATM) in Vitro

2003 • 91 citations

Memory by modification: the influence of chromatin structure on gene expression during vertebrate development

2003 • 42 citations

Dose-Rate Effect for DNA Damage Induced by Ionizing Radiation in Human Tumor Cells

1994 • 40 citations

Linear Induction of DNA Double-Strand Breakage with X-Ray Dose, as Determined from DNA Fragment Size Distribution

1995 • 37 citations

PI3K-Related Kinases: Roles in Cell-Cycle Regulation and DNA Damage Responses

2003 • 17 citations