Specific Amino Acid Substitutions in the S Protein Prevent Its Excretion In Vitro and May Contribute to Occult Hepatitis B Virus Infection

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

2011 • 5,243 citations

Statements from the Taormina expert meeting on occult hepatitis B virus infection

2008 • 789 citations

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

1989 • 692 citations

Prediction of Transmembrane Segments in Proteins Utilising Multiple Sequence Alignments

1994 • 466 citations

Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage

2004 • 288 citations

Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.

1991 • 215 citations

The virological and clinical significance of mutations in the overlapping envelope and polymerase genes of hepatitis B virus

2002 • 196 citations

Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors

2012 • 174 citations

Occult hepatitis B virus infection in chronic liver disease: Full-length genome and analysis of mutant surface promoter

2004 • 161 citations

Molecular and functional analysis of occult hepatitis B virus isolates from patients with hepatocellular carcinoma

2007 • 155 citations

Morphogenesis of hepatitis B virus and its subviral envelope particles

2009 • 136 citations

A 2010 update on occult hepatitis B infection

2010 • 130 citations

Characterization of occult hepatitis B virus from blood donors carrying genotype A2 or genotype D strains

2008 • 124 citations

Impact of hepatitis B virus surface protein mutations on the diagnosis of occult hepatitis B virus infection

2010 • 112 citations

A Function Essential to Viral Entry Underlies the Hepatitis B Virus “a” Determinant

2009 • 104 citations

Occult hepatitis B infection in blood donors from South East Asia: molecular characterisation and potential mechanisms of occurrence

2012 • 102 citations

Impairment of Hepatitis B Virus Virion Secretion by Single-Amino-Acid Substitutions in the Small Envelope Protein and Rescue by a Novel Glycosylation Site

2010 • 100 citations

Functional analysis of hepatitis B virus reactivating in hepatitis B surface antigen-negative individuals

2005 • 98 citations

A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis

2001 • 87 citations

Hepatitis B Virus Assembly Is Sensitive to Changes in the Cytosolic S Loop of the Envelope Proteins

2000 • 77 citations

Reduced Secretion of Virions and Hepatitis B Virus (HBV) Surface Antigen of a Naturally Occurring HBV Variant Correlates with the Accumulation of the Small S Envelope Protein in the Endoplasmic Reticulum and Golgi Apparatus

2005 • 74 citations

Modulation of Hepatitis B Virus Secretion by Naturally Occurring Mutations in the S Gene

2004 • 74 citations

Occult hepatitis B virus infection and lamivudine‐resistant mutations in isolates from renal patients undergoing hemodialysis

2009 • 71 citations

Molecular characterization and functional analysis of occult hepatitis B virus infection in Chinese patients infected with genotype C

2009 • 51 citations

Mutations associated with occult hepatitis B virus infection result in decreased surface antigen expression in vitro

2012 • 50 citations

Mutations in the Carboxyl-Terminal Domain of the Small Hepatitis B Virus Envelope Protein Impair the Assembly of Hepatitis Delta Virus Particles

1999 • 49 citations

Molecular and serological evaluation of surface antigen negative hepatitis B virus infection in blood donors from Venezuela

2004 • 39 citations

Role of Transmembrane Domains of Hepatitis B Virus Small Surface Proteins in Subviral-Particle Biogenesis

2012 • 29 citations

Expression of Hepatitis B Virus Surface Antigen Containing Y100C Variant Frequently Detected in Occult HBV Infection

2011 • 27 citations

A Unique Amino Acid Substitution, L215Q, in the Hepatitis B Virus Small Envelope Protein of a Genotype F Isolate That Inhibits Secretion of Hepatitis B Virus Subviral Particles

2008 • 3 citations