Oxidation of the Flavonoids Galangin and Kaempferide by Human Liver Microsomes and CYP1A1, CYP1A2, and CYP2C9

Flavonoids as Antioxidants

2000 • 4,578 citations

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1993 • 4,414 citations

Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands

1992 • 1,386 citations

Flavonoid intake and coronary mortality in Finland: a cohort study

1996 • 1,295 citations

Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices

1993 • 897 citations

Dietary Flavonoids and the Risk of Lung Cancer and Other Malignant Neoplasms

1997 • 779 citations

Human Cytochrome P450 Enzymes

1995 • 731 citations

Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study

1996 • 708 citations

Flavonoid Antioxidants

2001 • 680 citations

Intake of Flavonoids and Lung Cancer

2000 • 544 citations

Dietary Flavonoids, Antioxidant Vitamins, and Incidence of Stroke

1996 • 506 citations

Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially

1999 • 339 citations

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

1998 • 334 citations

Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1

2000 • 281 citations

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

1990 • 280 citations

Estimation of the Antioxidant Activities of Flavonoids from Their Oxidation Potentials

2001 • 278 citations

Transport of Quercetin and Its Glucosides across Human Intestinal Epithelial Caco-2 Cells

1998 • 251 citations

Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2

1999 • 249 citations

Consumption of onions and a reduced risk of stomach carcinoma

1996 • 222 citations

In vitrobiotransformation of flavonoids by rat liver microsomes

1998 • 182 citations

Flavones and flavonols at dietary levels inhibit a transformation of aryl hydrocarbon receptor induced by dioxin

2000 • 181 citations

The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor

1999 • 144 citations

Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells

1999 • 126 citations

Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids.

1998 • 120 citations

Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids

1994 • 112 citations

Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine

2001 • 100 citations

Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9.

1996 • 87 citations

Structure-Related Inhibition of Human Hepatic Caffeine N3-Demethylation by Naturally Occurring Flavonoids

1998 • 76 citations

Characterization of the inhibition of P4501A2 by furafylline

1994 • 73 citations

Involvement of rat cytochrome 1A1 in the biotransformation of kaempferol to quercetin: relevance to the genotoxicity of kaempferol

1997 • 69 citations

Metabolism of galangin by rat cytochromes P450: relevance to the genotoxicity of galangin

1997 • 43 citations

Quantitative Structure-Activity Relationships (QSAR) Study of Flavonoid Derivatives for Inhibition of Cytochrome P450 1A2

2000 • 37 citations

Formation of guanoxabenz from guanabenz in human liver. A new metabolic marker for CYP1A2.

1997 • 16 citations