Involvement of rat cytochrome 1A1 in the biotransformation of kaempferol to quercetin: relevance to the genotoxicity of kaempferol

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1993 • 4,414 citations

Flavonoids, a class of natural products of high pharmacological potency

1983 • 1,647 citations

Flavonoids are scavengers of superoxide anions

1988 • 1,596 citations

Flavonoids as Antioxidants

1994 • 1,172 citations

Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation

1989 • 967 citations

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

1995 • 601 citations

Relation between Intake of Flavonoids and Risk for Coronary Heart Disease in Male Health Professionals

1996 • 575 citations

Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin

1989 • 569 citations

Purification and characterization of hepatic microsomal cytochrome P-450

1990 • 379 citations

Quercetin Metabolites In Plasma of Rats Fed Diets Containing Rutin or Quercetin

1995 • 315 citations

Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.

1993 • 310 citations

Mutagenicity of plant flavonoids: Structural requirements for mutagenic activity in Salmonella typhimurium

1978 • 305 citations

Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids

1986 • 229 citations

Inhibition of glutathione reductase by flavonoids

1992 • 155 citations

Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.

1988 • 155 citations

Comparative mutagenesis of plant flavonoids in microbial systems

1978 • 145 citations

Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro

1983 • 116 citations

Inhibition of cytochrome P-450 activity in rat liver microsomes by the naturally occurring flavonoid, quercetin

1985 • 102 citations

Genetic toxicology of flavonoids: the role of metabolic conditions in the induction of reverse mutation, SOS functions and sisterchromatid exchanges

1986 • 78 citations

On the mechanisms of genotoxicity and metabolism of quercetin

1994 • 78 citations

Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

1996 • 74 citations

Effects of antioxidants on quercetin-induced nuclear DNA damage and lipid peroxidation

1991 • 59 citations

Mutagenicity of quercetin and kaempferol on cultured mammalian cells.

1979 • 48 citations

Interaction between quercetin and superoxide radicals. Reduction of the quercetin mutagenicity.

1984 • 43 citations

Expression of Cytochrome P450 mRNAs in the Colon and the Rectum in Normal Human Subjects

1995 • 41 citations

Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17β‐estradiol and 2‐aminofluorene in V79 Chinese hamster cells

1991 • 38 citations

Mutagenicity of kaempferol in V79 cells: The role of cytochromes P450

1996 • 29 citations

Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells

1994 • 27 citations

Mutagenicity of Quercetin and Kaempferol on Cultured Mammalian Cells

1979 • 27 citations

Urinary mutagenicity in occupational exposure to mineral oils and iron oxide particles

1982 • 23 citations

Mechanisms of myricetin mutagenicity in V79 cells: Involvement of radicalar species

1996 • 20 citations

PROOXIDANT ACTIVITIES OF FLAVONOLS: A STRUCTURE ACTIVITY STUDY

1996 • 6 citations

Flavonoids and Extracts of Strawberry and Black Currant are Inhibitors of the Carcinogen-Activating Enzyme Cyp1a1 in Vitro

2012 • 3 citations

Mutagenicity of kaempferol in V79 cells: The role of cytochromes P450

1996 • 2 citations