Lipid Rafts Determine Clustering of STIM1 in Endoplasmic Reticulum-Plasma Membrane Junctions and Regulation of Store-operated Ca2+ Entry (SOCE)

Lipid rafts and signal transduction

2000 • 6,079 citations

Calcium signalling: dynamics, homeostasis and remodelling

2003 • 5,215 citations

Store-Operated Calcium Channels

2005 • 2,077 citations

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

2005 • 2,020 citations

STIM1, an essential and conserved component of store-operated Ca2+ channel function

2005 • 1,757 citations

Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane

1998 • 1,502 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

2005 • 1,358 citations

Orai1 is an essential pore subunit of the CRAC channel

2006 • 1,305 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane

2006 • 772 citations

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions

2006 • 630 citations

STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

2006 • 627 citations

Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca ²⁺ store depletion

2007 • 592 citations

Emerging Themes in Lipid Rafts and Caveolae

2001 • 567 citations

CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel

2006 • 555 citations

The molecular choreography of a store-operated calcium channel

2007 • 502 citations

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

2007 • 491 citations

Recruitment of TNF Receptor 1 to Lipid Rafts Is Essential for TNFα-Mediated NF-κB Activation

2003 • 441 citations

Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains

2000 • 403 citations

Dynamic Assembly of TRPC1-STIM1-Orai1 Ternary Complex Is Involved in Store-operated Calcium Influx

2007 • 382 citations

The cellular and molecular basis of store-operated calcium entry

2002 • 366 citations

Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex

2007 • 247 citations

Mapping the Interacting Domains of STIM1 and Orai1 in Ca2+ Release-activated Ca2+ Channel Activation

2007 • 237 citations

TRPC1: The link between functionally distinct store-operated calcium channels

2007 • 231 citations

Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1

2006 • 225 citations

Recent breakthroughs in the molecular mechanism of capacitative calcium entry (with thoughts on how we got here)

2007 • 224 citations

Attenuation of store-operated Ca ²⁺ current impairs salivary gland fluid secretion in TRPC1(−/−) mice

2007 • 216 citations

TRPC channels as STIM1-regulated store-operated channels

2007 • 214 citations

Caveolin-1 Contributes to Assembly of Store-operated Ca2+ Influx Channels by Regulating Plasma Membrane Localization of TRPC1

2003 • 211 citations

TRPC1 Is Required for Functional Store-operated Ca2+ Channels

2003 • 181 citations

Genetic Evidence Supporting Caveolae Microdomain Regulation of Calcium Entry in Endothelial Cells

2007 • 153 citations

Function of Caveolae in Ca²⁺ Entry and Ca²⁺‐Dependent Signal Transduction

2003 • 131 citations

Dissecting ICRAC, a store-operated calcium current

2007 • 113 citations

Ca2+ signaling microdomains:platforms for the assembly andregulation of TRPC channels

2005 • 105 citations